418 related articles for article (PubMed ID: 25604624)
1. In vivo regulation of gene expression and T helper type 17 differentiation by RORγt inverse agonists.
Skepner J; Trocha M; Ramesh R; Qu XA; Schmidt D; Baloglu E; Lobera M; Davis S; Nolan MA; Carlson TJ; Hill J; Ghosh S; Sundrud MS; Yang J
Immunology; 2015 Jul; 145(3):347-56. PubMed ID: 25604624
[TBL] [Abstract][Full Text] [Related]
2. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo.
Skepner J; Ramesh R; Trocha M; Schmidt D; Baloglu E; Lobera M; Carlson T; Hill J; Orband-Miller LA; Barnes A; Boudjelal M; Sundrud M; Ghosh S; Yang J
J Immunol; 2014 Mar; 192(6):2564-75. PubMed ID: 24516202
[TBL] [Abstract][Full Text] [Related]
3. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.
Xiao S; Yosef N; Yang J; Wang Y; Zhou L; Zhu C; Wu C; Baloglu E; Schmidt D; Ramesh R; Lobera M; Sundrud MS; Tsai PY; Xiang Z; Wang J; Xu Y; Lin X; Kretschmer K; Rahl PB; Young RA; Zhong Z; Hafler DA; Regev A; Ghosh S; Marson A; Kuchroo VK
Immunity; 2014 Apr; 40(4):477-89. PubMed ID: 24745332
[TBL] [Abstract][Full Text] [Related]
4. Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo.
Guendisch U; Weiss J; Ecoeur F; Riker JC; Kaupmann K; Kallen J; Hintermann S; Orain D; Dawson J; Billich A; Guntermann C
PLoS One; 2017; 12(11):e0188391. PubMed ID: 29155882
[TBL] [Abstract][Full Text] [Related]
5. AT-rich-interactive domain-containing protein 5A functions as a negative regulator of retinoic acid receptor-related orphan nuclear receptor γt-induced Th17 cell differentiation.
Saito Y; Kagami S; Sanayama Y; Ikeda K; Suto A; Kashiwakuma D; Furuta S; Iwamoto I; Nonaka K; Ohara O; Nakajima H
Arthritis Rheumatol; 2014 May; 66(5):1185-94. PubMed ID: 24782182
[TBL] [Abstract][Full Text] [Related]
6. Concomitant suppression of T
Na H; Lim H; Choi G; Kim BK; Kim SH; Chang YS; Nurieva R; Dong C; Chang SH; Chung Y
J Allergy Clin Immunol; 2018 Jun; 141(6):2061-2073.e5. PubMed ID: 28943467
[TBL] [Abstract][Full Text] [Related]
7. Antagonizing Retinoic Acid-Related-Orphan Receptor Gamma Activity Blocks the T Helper 17/Interleukin-17 Pathway Leading to Attenuated Pro-inflammatory Human Keratinocyte and Skin Responses.
Ecoeur F; Weiss J; Kaupmann K; Hintermann S; Orain D; Guntermann C
Front Immunol; 2019; 10():577. PubMed ID: 30972071
[TBL] [Abstract][Full Text] [Related]
8. Targeting Th17 Cells with Small Molecules and Small Interference RNA.
Lin H; Song P; Zhao Y; Xue LJ; Liu Y; Chu CQ
Mediators Inflamm; 2015; 2015():290657. PubMed ID: 26792955
[TBL] [Abstract][Full Text] [Related]
9. A novel human truncated IL12rβ1-Fc fusion protein ameliorates experimental autoimmune encephalomyelitis via specific binding of p40 to inhibit Th1 and Th17 cell differentiation.
Guo W; Wang C; Wang X; Luo C; Yu D; Wang Y; Chen Y; Lei W; Gao X; Yao W
Oncotarget; 2015 Oct; 6(30):28539-55. PubMed ID: 26384304
[TBL] [Abstract][Full Text] [Related]
10. Identification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing RORγt Activity and Suppressing Th17 Cell Differentiation.
Ding Q; Zhao M; Yu B; Bai C; Huang Z
PLoS One; 2015; 10(9):e0137711. PubMed ID: 26368822
[TBL] [Abstract][Full Text] [Related]
11. Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
Tan J; Liu H; Huang M; Li N; Tang S; Meng J; Tang S; Zhou H; Kijlstra A; Yang P; Hou S
Cell Death Dis; 2020 Aug; 11(8):697. PubMed ID: 32829384
[TBL] [Abstract][Full Text] [Related]
12. RORγt-specific transcriptional interactomic inhibition suppresses autoimmunity associated with TH17 cells.
Park TY; Park SD; Cho JY; Moon JS; Kim NY; Park K; Seong RH; Lee SW; Morio T; Bothwell AL; Lee SK
Proc Natl Acad Sci U S A; 2014 Dec; 111(52):18673-8. PubMed ID: 25527718
[TBL] [Abstract][Full Text] [Related]
13. Novel benzenediamine derivative FC99 ameliorates zymosan-induced arthritis by inhibiting RORγt expression and Th17 cell differentiation.
Ji J; Dou H; Li X; Song Y; Li X; Li E; Tan R; Hou Y
Acta Biochim Biophys Sin (Shanghai); 2014 Oct; 46(10):829-36. PubMed ID: 25187413
[TBL] [Abstract][Full Text] [Related]
14. microRNA cluster 106a~363 is involved in T helper 17 cell differentiation.
Kästle M; Bartel S; Geillinger-Kästle K; Irmler M; Beckers J; Ryffel B; Eickelberg O; Krauss-Etschmann S
Immunology; 2017 Nov; 152(3):402-413. PubMed ID: 28617945
[TBL] [Abstract][Full Text] [Related]
15. Generation of RORγt
Kim BS; Lu H; Ichiyama K; Chen X; Zhang YB; Mistry NA; Tanaka K; Lee YH; Nurieva R; Zhang L; Yang X; Chung Y; Jin W; Chang SH; Dong C
Cell Rep; 2017 Oct; 21(1):195-207. PubMed ID: 28978473
[TBL] [Abstract][Full Text] [Related]
16. Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin.
Bovenschen HJ; van de Kerkhof PC; van Erp PE; Woestenenk R; Joosten I; Koenen HJ
J Invest Dermatol; 2011 Sep; 131(9):1853-60. PubMed ID: 21654831
[TBL] [Abstract][Full Text] [Related]
17. Signaling Pathways and Epigenetic Regulations in the Control of RORγt Expression in T Helper 17 Cells.
Tian Y; Wu Y; Ni B
Int Rev Immunol; 2015; 34(4):305-17. PubMed ID: 24801756
[TBL] [Abstract][Full Text] [Related]
18. IL-12 inhibits the TGF-β-dependent T cell developmental programs and skews the TGF-β-induced differentiation into a Th1-like direction.
Prochazkova J; Pokorna K; Holan V
Immunobiology; 2012 Jan; 217(1):74-82. PubMed ID: 21903294
[TBL] [Abstract][Full Text] [Related]
19. Yin-Yang Regulation of RORγt Protein Complex in Th17 Differentiation.
Gao W; Wu Y; Tian Y; Ni B
Int Rev Immunol; 2015; 34(4):295-304. PubMed ID: 25340306
[TBL] [Abstract][Full Text] [Related]
20. The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor γt (RORγt) in Th17 cells.
Han L; Yang J; Wang X; Wu Q; Yin S; Li Z; Zhang J; Xing Y; Chen Z; Tsun A; Li D; Piccioni M; Zhang Y; Guo Q; Jiang L; Bao L; Lv L; Li B
J Biol Chem; 2014 Sep; 289(37):25546-55. PubMed ID: 25070893
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
