BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

2403 related articles for article (PubMed ID: 25609923)

  • 1. Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
    Yuan CX; Zhou ZW; Yang YX; He ZX; Zhang X; Wang D; Yang T; Wang NJ; Zhao RJ; Zhou SF
    Drug Des Devel Ther; 2015; 9():487-508. PubMed ID: 25609923
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells.
    Yuan CX; Zhou ZW; Yang YX; He ZX; Zhang X; Wang D; Yang T; Pan SY; Chen XW; Zhou SF
    Drug Des Devel Ther; 2015; 9():1293-318. PubMed ID: 25767376
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP; Yang YX; Liu QL; Pan ST; He ZX; Zhang X; Yang T; Chen XW; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1627-52. PubMed ID: 25834401
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F; Li H; Yan XG; Zhou ZW; Yi ZG; He ZX; Pan ST; Yang YX; Wang ZZ; Zhang X; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():575-601. PubMed ID: 25632225
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.
    Ding YH; Zhou ZW; Ha CF; Zhang XY; Pan ST; He ZX; Edelman JL; Wang D; Yang YX; Zhang X; Duan W; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():425-64. PubMed ID: 25624750
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.
    Ren BJ; Zhou ZW; Zhu DJ; Ju YL; Wu JH; Ouyang MZ; Chen XW; Zhou SF
    Int J Mol Sci; 2015 Dec; 17(1):. PubMed ID: 26729093
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
    Wang F; Wang Q; Zhou ZW; Yu SN; Pan ST; He ZX; Zhang X; Wang D; Yang YX; Yang T; Sun T; Li M; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():537-60. PubMed ID: 25632222
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST; Qin Y; Zhou ZW; He ZX; Zhang X; Yang T; Yang YX; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1601-26. PubMed ID: 25834400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Alisertib induces G
    Liu Z; Wang F; Zhou ZW; Xia HC; Wang XY; Yang YX; He ZX; Sun T; Zhou SF
    Am J Transl Res; 2017; 9(3):845-873. PubMed ID: 28386317
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alisertib induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells.
    Fu Y; Zhang Y; Gao M; Quan L; Gui R; Liu J
    Mol Med Rep; 2016 Jul; 14(1):394-8. PubMed ID: 27177156
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells.
    Li JP; Yang YX; Liu QL; Zhou ZW; Pan ST; He ZX; Zhang X; Yang T; Pan SY; Duan W; He SM; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1027-62. PubMed ID: 25733818
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of Aurora A Kinase by Alisertib Induces Autophagy and Cell Cycle Arrest and Increases Chemosensitivity in Human Hepatocellular Carcinoma HepG2 Cells.
    Zhu Q; Yu X; Zhou ZW; Zhou C; Chen XW; Zhou SF
    Curr Cancer Drug Targets; 2017; 17(4):386-401. PubMed ID: 27396604
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pectolinarigenin Induced Cell Cycle Arrest, Autophagy, and Apoptosis in Gastric Cancer Cell via PI3K/AKT/mTOR Signaling Pathway.
    Lee HJ; Venkatarame Gowda Saralamma V; Kim SM; Ha SE; Raha S; Lee WS; Kim EH; Lee SJ; Heo JD; Kim GS
    Nutrients; 2018 Aug; 10(8):. PubMed ID: 30096805
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Danusertib Induces Apoptosis, Cell Cycle Arrest, and Autophagy but Inhibits Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR Signaling Pathway in Human Ovarian Cancer Cells.
    Zi D; Zhou ZW; Yang YJ; Huang L; Zhou ZL; He SM; He ZX; Zhou SF
    Int J Mol Sci; 2015 Nov; 16(11):27228-51. PubMed ID: 26580601
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Apigetrin induces extrinsic apoptosis, autophagy and G2/M phase cell cycle arrest through PI3K/AKT/mTOR pathway in AGS human gastric cancer cell.
    Kim SM; Vetrivel P; Ha SE; Kim HH; Kim JA; Kim GS
    J Nutr Biochem; 2020 Sep; 83():108427. PubMed ID: 32559585
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells.
    Nagappan A; Lee WS; Yun JW; Lu JN; Chang SH; Jeong JH; Kim GS; Jung JM; Hong SC
    PLoS One; 2017; 12(3):e0174591. PubMed ID: 28355296
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway.
    Rong L; Li Z; Leng X; Li H; Ma Y; Chen Y; Song F
    Biomed Pharmacother; 2020 Feb; 122():109726. PubMed ID: 31918283
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Resveratrol induces apoptosis and autophagy in T-cell acute lymphoblastic leukemia cells by inhibiting Akt/mTOR and activating p38-MAPK.
    Ge J; Liu Y; Li Q; Guo X; Gu L; Ma ZG; Zhu YP
    Biomed Environ Sci; 2013 Nov; 26(11):902-11. PubMed ID: 24331535
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Euptox A Induces G1 Arrest and Autophagy via p38 MAPK- and PI3K/Akt/mTOR-Mediated Pathways in Mouse Splenocytes.
    Mo Q; Hu L; Weng J; Zhang Y; Zhou Y; Xu R; Zuo Z; Deng J; Ren Z; Zhong Z; Peng G; Nong X; Wei Y; Hu Y
    J Histochem Cytochem; 2017 Sep; 65(9):543-558. PubMed ID: 28745544
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 121.