These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 25612740)

  • 1. Increased mitochondrial DNA deletions in substantia nigra dopamine neurons of the aged rat.
    Parkinson GM; Dayas CV; Smith DW
    Curr Aging Sci; 2014; 7(3):155-60. PubMed ID: 25612740
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Accumulation of mitochondrial DNA deletions within dopaminergic neurons triggers neuroprotective mechanisms.
    Perier C; Bender A; García-Arumí E; Melià MJ; Bové J; Laub C; Klopstock T; Elstner M; Mounsey RB; Teismann P; Prolla T; Andreu AL; Vila M
    Brain; 2013 Aug; 136(Pt 8):2369-78. PubMed ID: 23884809
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Age-related gene expression changes in substantia nigra dopamine neurons of the rat.
    Parkinson GM; Dayas CV; Smith DW
    Mech Ageing Dev; 2015 Jul; 149():41-9. PubMed ID: 26065381
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Parkin deficiency accelerates consequences of mitochondrial DNA deletions and Parkinsonism.
    Song L; McMackin M; Nguyen A; Cortopassi G
    Neurobiol Dis; 2017 Apr; 100():30-38. PubMed ID: 28042097
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dopaminergic midbrain neurons are the prime target for mitochondrial DNA deletions.
    Bender A; Schwarzkopf RM; McMillan A; Krishnan KJ; Rieder G; Neumann M; Elstner M; Turnbull DM; Klopstock T
    J Neurol; 2008 Aug; 255(8):1231-5. PubMed ID: 18604467
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Catecholamine metabolism drives generation of mitochondrial DNA deletions in dopaminergic neurons.
    Neuhaus JF; Baris OR; Hess S; Moser N; Schröder H; Chinta SJ; Andersen JK; Kloppenburg P; Wiesner RJ
    Brain; 2014 Feb; 137(Pt 2):354-65. PubMed ID: 24163249
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitochondrial DNA deletions/rearrangements in parkinson disease and related neurodegenerative disorders.
    Gu G; Reyes PE; Golden GT; Woltjer RL; Hulette C; Montine TJ; Zhang J
    J Neuropathol Exp Neurol; 2002 Jul; 61(7):634-9. PubMed ID: 12125742
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant Twinkle increases dopaminergic neurodegeneration, mtDNA deletions and modulates Parkin expression.
    Song L; Shan Y; Lloyd KC; Cortopassi GA
    Hum Mol Genet; 2012 Dec; 21(23):5147-58. PubMed ID: 22949510
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The low abundance of clonally expanded mitochondrial DNA point mutations in aged substantia nigra neurons.
    Reeve AK; Krishnan KJ; Taylor G; Elson JL; Bender A; Taylor RW; Morris CM; Turnbull DM
    Aging Cell; 2009 Aug; 8(4):496-8. PubMed ID: 19489744
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The impact of pathogenic mitochondrial DNA mutations on substantia nigra neurons.
    Reeve A; Meagher M; Lax N; Simcox E; Hepplewhite P; Jaros E; Turnbull D
    J Neurosci; 2013 Jun; 33(26):10790-801. PubMed ID: 23804100
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ultradeep mapping of neuronal mitochondrial deletions in Parkinson's disease.
    Nido GS; Dölle C; Flønes I; Tuppen HA; Alves G; Tysnes OB; Haugarvoll K; Tzoulis C
    Neurobiol Aging; 2018 Mar; 63():120-127. PubMed ID: 29257976
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitochondrial DNA deletions in mice in men: substantia nigra is much less affected in the mouse.
    Guo X; Kudryavtseva E; Bodyak N; Nicholas A; Dombrovsky I; Yang D; Kraytsberg Y; Simon DK; Khrapko K
    Biochim Biophys Acta; 2010; 1797(6-7):1159-62. PubMed ID: 20388490
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.
    Kraytsberg Y; Kudryavtseva E; McKee AC; Geula C; Kowall NW; Khrapko K
    Nat Genet; 2006 May; 38(5):518-20. PubMed ID: 16604072
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neuromelanin, neurotransmitter status and brainstem location determine the differential vulnerability of catecholaminergic neurons to mitochondrial DNA deletions.
    Elstner M; Müller SK; Leidolt L; Laub C; Krieg L; Schlaudraff F; Liss B; Morris C; Turnbull DM; Masliah E; Prokisch H; Klopstock T; Bender A
    Mol Brain; 2011 Dec; 4():43. PubMed ID: 22188897
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitochondrial DNA homeostasis is essential for nigrostriatal integrity.
    Tzoulis C; Schwarzlmüller T; Biermann M; Haugarvoll K; Bindoff LA
    Mitochondrion; 2016 May; 28():33-7. PubMed ID: 26979109
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease.
    Simon DK; Lin MT; Zheng L; Liu GJ; Ahn CH; Kim LM; Mauck WM; Twu F; Beal MF; Johns DR
    Neurobiol Aging; 2004 Jan; 25(1):71-81. PubMed ID: 14675733
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nature of mitochondrial DNA deletions in substantia nigra neurons.
    Reeve AK; Krishnan KJ; Elson JL; Morris CM; Bender A; Lightowlers RN; Turnbull DM
    Am J Hum Genet; 2008 Jan; 82(1):228-35. PubMed ID: 18179904
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease.
    Bender A; Krishnan KJ; Morris CM; Taylor GA; Reeve AK; Perry RH; Jaros E; Hersheson JS; Betts J; Klopstock T; Taylor RW; Turnbull DM
    Nat Genet; 2006 May; 38(5):515-7. PubMed ID: 16604074
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterisation of mitochondrial DNA deletions by long-PCR in central nervous system regions of young, middle- and old-aged rats.
    Cahif A; Parkinson GM; Dayas CV; Smith DW
    Curr Aging Sci; 2013 Dec; 6(3):232-8. PubMed ID: 24304200
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Catecholamine Metabolism Induces Mitochondrial DNA Deletions and Leads to Severe Adrenal Degeneration during Aging.
    Neuhaus JF; Baris OR; Kittelmann A; Becker K; Rothschild MA; Wiesner RJ
    Neuroendocrinology; 2017; 104(1):72-84. PubMed ID: 26895241
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.