BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

26 related articles for article (PubMed ID: 25615400)

  • 1. Mechanisms of topoisomerase I (TOP1) gene copy number increase in a stage III colorectal cancer patient cohort.
    Smith DH; Christensen IJ; Jensen NF; Markussen B; Rømer MU; Nygård SB; Müller S; Nielsen HJ; Brünner N; Nielsen KV
    PLoS One; 2013; 8(4):e60613. PubMed ID: 23577133
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Publisher Correction: Signatures of TOP1 transcription-associated mutagenesis in cancer and germline.
    Reijns MAM; Parry DA; Williams TC; Nadeu F; Hindshaw RL; Rios Szwed DO; Nicholson MD; Carroll P; Boyle S; Royo R; Cornish AJ; Xiang H; Ridout K; ; ; Schuh A; Aden K; Palles C; Campo E; Stankovic T; Taylor MS; Jackson AP
    Nature; 2022 May; 605(7910):E7. PubMed ID: 35504971
    [No Abstract]   [Full Text] [Related]  

  • 3. Targeting Topoisomerase I in the Era of Precision Medicine.
    Thomas A; Pommier Y
    Clin Cancer Res; 2019 Nov; 25(22):6581-6589. PubMed ID: 31227499
    [TBL] [Abstract][Full Text] [Related]  

  • 4. G-quadruplexes on chromosomal DNA negatively regulates topoisomerase 1 activity.
    Liang HT; Yan JY; Yao HJ; Zhang XN; Xing ZM; Liu L; Chen YQ; Li GR; Huang J; He YD; Zheng KW
    Nucleic Acids Res; 2024 Mar; 52(5):2142-2156. PubMed ID: 38340342
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Topoisomerase 1-dependent R-loop deficiency drives accelerated replication and genomic instability.
    Sarni D; Barroso S; Shtrikman A; Irony-Tur Sinai M; Oren YS; Aguilera A; Kerem B
    Cell Rep; 2022 Sep; 40(13):111397. PubMed ID: 36170822
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Humanized Yeast Phenomic Model of Deoxycytidine Kinase to Predict Genetic Buffering of Nucleoside Analog Cytotoxicity.
    Santos SM; Icyuz M; Pound I; William D; Guo J; McKinney BA; Niederweis M; Rodgers J; Hartman JL
    Genes (Basel); 2019 Sep; 10(10):. PubMed ID: 31575041
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Top1 paradox: Friend and foe of the eukaryotic genome.
    Kim N; Jinks-Robertson S
    DNA Repair (Amst); 2017 Aug; 56():33-41. PubMed ID: 28641942
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FOLFIRINOX and translational studies: Towards personalized therapy in pancreatic cancer.
    Caparello C; Meijer LL; Garajova I; Falcone A; Le Large TY; Funel N; Kazemier G; Peters GJ; Vasile E; Giovannetti E
    World J Gastroenterol; 2016 Aug; 22(31):6987-7005. PubMed ID: 27610011
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis.
    Rømer MU; Nygård SB; Christensen IJ; Nielsen SL; Nielsen KV; Müller S; Smith DH; Vainer B; Nielsen HJ; Brünner N
    Mol Oncol; 2013 Feb; 7(1):101-11. PubMed ID: 23110915
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Assessment of the topoisomerase I gene copy number as a predictive biomarker of objective response to irinotecan in metastatic colorectal cancer.
    Nygård SB; Christensen IJ; Nielsen SL; Nielsen HJ; Brünner N; Spindler KL
    Scand J Gastroenterol; 2014 Jan; 49(1):84-91. PubMed ID: 24256029
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanisms of resistance to topoisomerase I-targeting drugs.
    Rasheed ZA; Rubin EH
    Oncogene; 2003 Oct; 22(47):7296-304. PubMed ID: 14576839
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas.
    Grunnet M; Calatayud D; Schultz NA; Hasselby JP; Mau-Sørensen M; Brünner N; Stenvang J
    Scand J Gastroenterol; 2015 Apr; 50(4):485-94. PubMed ID: 25615400
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer.
    Kümler I; Balslev E; Poulsen TS; Nielsen SL; Nygård SB; Rømer MU; Christensen IJ; Høgdall E; Moreira J; Nielsen DL; Brünner N; Stenvang J
    Int J Cancer; 2015 Oct; 137(8):2000-6. PubMed ID: 25855483
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer.
    Palshof JA; Høgdall EV; Poulsen TS; Linnemann D; Jensen BV; Pfeiffer P; Tarpgaard LS; Brünner N; Stenvang J; Yilmaz M; Nielsen DL
    BMC Cancer; 2017 Jan; 17(1):48. PubMed ID: 28077117
    [TBL] [Abstract][Full Text] [Related]  

  • 15.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 16.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 17.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 18.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 19.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 2.