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2. The role of substrate strain in the mechanism of the carbon-carbon lyases. Phillips RS; Demidkina TV; Faleev NG Bioorg Chem; 2014 Dec; 57():198-205. PubMed ID: 25035301 [TBL] [Abstract][Full Text] [Related]
3. Characterization of aminoacrylate intermediates of pyridoxal-5'-phosphate dependent enzymes. Phillips RS; Bauer O Methods Enzymol; 2023; 685():199-224. PubMed ID: 37245902 [TBL] [Abstract][Full Text] [Related]
7. The phosphate of pyridoxal-5'-phosphate is an acid/base catalyst in the mechanism of Pseudomonas fluorescens kynureninase. Phillips RS; Scott I; Paulose R; Patel A; Barron TC FEBS J; 2014 Feb; 281(4):1100-9. PubMed ID: 24304904 [TBL] [Abstract][Full Text] [Related]
8. Role of the pyridine nitrogen in pyridoxal 5'-phosphate catalysis: activity of three classes of PLP enzymes reconstituted with deazapyridoxal 5'-phosphate. Griswold WR; Toney MD J Am Chem Soc; 2011 Sep; 133(37):14823-30. PubMed ID: 21827189 [TBL] [Abstract][Full Text] [Related]
9. Role of lysine-256 in Citrobacter freundii tyrosine phenol-lyase in monovalent cation activation. Phillips RS; Chen HY; Shim D; Lima S; Tavakoli K; Sundararaju B Biochemistry; 2004 Nov; 43(45):14412-9. PubMed ID: 15533046 [TBL] [Abstract][Full Text] [Related]
10. Crystallographic snapshots of tyrosine phenol-lyase show that substrate strain plays a role in C-C bond cleavage. Milić D; Demidkina TV; Faleev NG; Phillips RS; Matković-Čalogović D; Antson AA J Am Chem Soc; 2011 Oct; 133(41):16468-76. PubMed ID: 21899319 [TBL] [Abstract][Full Text] [Related]
11. Site-directed mutagenesis of tyrosine-71 to phenylalanine in Citrobacter freundii tyrosine phenol-lyase: evidence for dual roles of tyrosine-71 as a general acid catalyst in the reaction mechanism and in cofactor binding. Chen HY; Demidkina TV; Phillips RS Biochemistry; 1995 Sep; 34(38):12276-83. PubMed ID: 7547970 [TBL] [Abstract][Full Text] [Related]
12. The roles of Ser-36, Asp-132 and Asp-201 in the reaction of Pseudomonas fluorescens Kynureninase. Phillips RS; Crocker M; Lin R; Idowu OE; McCannon DK; Lima S Biochim Biophys Acta Proteins Proteom; 2019; 1867(7-8):722-731. PubMed ID: 31100408 [TBL] [Abstract][Full Text] [Related]
13. Stereospecificity of isotopic exchange of C-α-protons of glycine catalyzed by three PLP-dependent lyases: the unusual case of tyrosine phenol-lyase. Koulikova VV; Zakomirdina LN; Gogoleva OI; Tsvetikova MA; Morozova EA; Komissarov VV; Tkachev YV; Timofeev VP; Demidkina TV; Faleev NG Amino Acids; 2011 Nov; 41(5):1247-56. PubMed ID: 21104284 [TBL] [Abstract][Full Text] [Related]
14. Citrobacter freundii tyrosine phenol-lyase: the role of asparagine 185 in modulating enzyme function through stabilization of a quinonoid intermediate. Barbolina MV; Phillips RS; Gollnick PD; Faleev NG; Demidkina TV Protein Eng; 2000 Mar; 13(3):207-15. PubMed ID: 10775663 [TBL] [Abstract][Full Text] [Related]
16. Crystal Structures of Wild-Type and F448A Mutant Citrobacter freundii Tyrosine Phenol-Lyase Complexed with a Substrate and Inhibitors: Implications for the Reaction Mechanism. Phillips RS; Craig S Biochemistry; 2018 Oct; 57(43):6166-6179. PubMed ID: 30260636 [TBL] [Abstract][Full Text] [Related]
17. The crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificity. Sundararaju B; Antson AA; Phillips RS; Demidkina TV; Barbolina MV; Gollnick P; Dodson GG; Wilson KS Biochemistry; 1997 May; 36(21):6502-10. PubMed ID: 9174368 [TBL] [Abstract][Full Text] [Related]
18. Pyridoxal phosphate-dependent reactions in the biosynthesis of natural products. Du YL; Ryan KS Nat Prod Rep; 2019 Mar; 36(3):430-457. PubMed ID: 30183796 [TBL] [Abstract][Full Text] [Related]
19. Three-dimensional structure of kynureninase from Pseudomonas fluorescens. Momany C; Levdikov V; Blagova L; Lima S; Phillips RS Biochemistry; 2004 Feb; 43(5):1193-203. PubMed ID: 14756555 [TBL] [Abstract][Full Text] [Related]
20. Insights into the catalytic mechanism of tyrosine phenol-lyase from X-ray structures of quinonoid intermediates. Milić D; Demidkina TV; Faleev NG; Matković-Calogović D; Antson AA J Biol Chem; 2008 Oct; 283(43):29206-14. PubMed ID: 18715865 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]