223 related articles for article (PubMed ID: 25618348)
1. Practical strategies for small-molecule probe development in chemical biology.
Hempel JE; Hong CC
Methods Mol Biol; 2015; 1263():209-23. PubMed ID: 25618348
[TBL] [Abstract][Full Text] [Related]
2. [The application of small molecule bioactive probes in the identification of cellular targets].
Zhang J; Zhou HC
Yao Xue Xue Bao; 2012 Mar; 47(3):299-306. PubMed ID: 22645752
[TBL] [Abstract][Full Text] [Related]
3. The three cornerstones of chemical biology: innovative probes, new discoveries, and enabling tools.
Thompson AD; Makley LN; McMenimen K; Gestwicki JE
ACS Chem Biol; 2012 May; 7(5):791-6. PubMed ID: 22594530
[No Abstract] [Full Text] [Related]
4. A crowdsourcing evaluation of the NIH chemical probes.
Oprea TI; Bologa CG; Boyer S; Curpan RF; Glen RC; Hopkins AL; Lipinski CA; Marshall GR; Martin YC; Ostopovici-Halip L; Rishton G; Ursu O; Vaz RJ; Waller C; Waldmann H; Sklar LA
Nat Chem Biol; 2009 Jul; 5(7):441-7. PubMed ID: 19536101
[TBL] [Abstract][Full Text] [Related]
5. Small molecules and their role in effective preclinical target validation.
Clegg MA; Tomkinson NC; Prinjha RK; Humphreys PG
Future Med Chem; 2017 Sep; 9(14):1579-1582. PubMed ID: 28828889
[No Abstract] [Full Text] [Related]
6. Target identification of bioactive compounds.
Tashiro E; Imoto M
Bioorg Med Chem; 2012 Mar; 20(6):1910-21. PubMed ID: 22104438
[TBL] [Abstract][Full Text] [Related]
7. Chemical Biology Probes from Advanced DNA-encoded Libraries.
Salamon H; Klika Škopić M; Jung K; Bugain O; Brunschweiger A
ACS Chem Biol; 2016 Feb; 11(2):296-307. PubMed ID: 26820267
[TBL] [Abstract][Full Text] [Related]
8. From Phenotypic Hit to Chemical Probe: Chemical Biology Approaches to Elucidate Small Molecule Action in Complex Biological Systems.
Pasquer QTL; Tsakoumagkos IA; Hoogendoorn S
Molecules; 2020 Dec; 25(23):. PubMed ID: 33287212
[TBL] [Abstract][Full Text] [Related]
9. Small molecule chemical probes of microRNA function.
Velagapudi SP; Vummidi BR; Disney MD
Curr Opin Chem Biol; 2015 Feb; 24():97-103. PubMed ID: 25500006
[TBL] [Abstract][Full Text] [Related]
10. Ligand and Target Discovery by Fragment-Based Screening in Human Cells.
Parker CG; Galmozzi A; Wang Y; Correia BE; Sasaki K; Joslyn CM; Kim AS; Cavallaro CL; Lawrence RM; Johnson SR; Narvaiza I; Saez E; Cravatt BF
Cell; 2017 Jan; 168(3):527-541.e29. PubMed ID: 28111073
[TBL] [Abstract][Full Text] [Related]
11. Fragment Hits: What do They Look Like and How do They Bind?
Giordanetto F; Jin C; Willmore L; Feher M; Shaw DE
J Med Chem; 2019 Apr; 62(7):3381-3394. PubMed ID: 30875465
[TBL] [Abstract][Full Text] [Related]
12. Advances in discovering small molecules to probe protein function in a systems context.
Doyle SK; Pop MS; Evans HL; Koehler AN
Curr Opin Chem Biol; 2016 Feb; 30():28-36. PubMed ID: 26615565
[TBL] [Abstract][Full Text] [Related]
13. Identification of protein binding partners of small molecules using label-free methods.
Saxena C
Expert Opin Drug Discov; 2016 Oct; 11(10):1017-25. PubMed ID: 27554241
[TBL] [Abstract][Full Text] [Related]
14. New developments in the discovery of small molecule Hedgehog pathway antagonists.
Tremblay MR; McGovern K; Read MA; Castro AC
Curr Opin Chem Biol; 2010 Jun; 14(3):428-35. PubMed ID: 20399136
[TBL] [Abstract][Full Text] [Related]
15. Identification of the targets of biologically active small molecules using quantitative proteomics.
Vendrell-Navarro G; Brockmeyer A; Waldmann H; Janning P; Ziegler S
Methods Mol Biol; 2015; 1263():263-86. PubMed ID: 25618352
[TBL] [Abstract][Full Text] [Related]
16. Identification and validation of bioactive small molecule target through phenotypic screening.
Cho YS; Kwon HJ
Bioorg Med Chem; 2012 Mar; 20(6):1922-8. PubMed ID: 22153994
[TBL] [Abstract][Full Text] [Related]
17. Efficiency of hit generation and structural characterization in fragment-based ligand discovery.
Larsson A; Jansson A; Åberg A; Nordlund P
Curr Opin Chem Biol; 2011 Aug; 15(4):482-8. PubMed ID: 21724447
[TBL] [Abstract][Full Text] [Related]
18. Target Identification Using Chemical Probes.
Moustakim M; Felce SL; Zaarour N; Farnie G; McCann FE; Brennan PE
Methods Enzymol; 2018; 610():27-58. PubMed ID: 30390803
[TBL] [Abstract][Full Text] [Related]
19. Hit finding: towards 'smarter' approaches.
Langer T; Hoffmann R; Bryant S; Lesur B
Curr Opin Pharmacol; 2009 Oct; 9(5):589-93. PubMed ID: 19576852
[TBL] [Abstract][Full Text] [Related]
20. [Chemical libraries dedicated to protein-protein interactions].
Sperandio O; Villoutreix BO; Morelli X; Roche P
Med Sci (Paris); 2015 Mar; 31(3):312-9. PubMed ID: 25855285
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]