293 related articles for article (PubMed ID: 25619277)
1. How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state.
Giardina G; Brunotti P; Fiascarelli A; Cicalini A; Costa MG; Buckle AM; di Salvo ML; Giorgi A; Marani M; Paone A; Rinaldo S; Paiardini A; Contestabile R; Cutruzzolà F
FEBS J; 2015 Apr; 282(7):1225-41. PubMed ID: 25619277
[TBL] [Abstract][Full Text] [Related]
2. Conformational transitions driven by pyridoxal-5'-phosphate uptake in the psychrophilic serine hydroxymethyltransferase from Psychromonas ingrahamii.
Angelaccio S; Dworkowski F; Di Bello A; Milano T; Capitani G; Pascarella S
Proteins; 2014 Oct; 82(10):2831-41. PubMed ID: 25044250
[TBL] [Abstract][Full Text] [Related]
3. The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy.
Renwick SB; Snell K; Baumann U
Structure; 1998 Sep; 6(9):1105-16. PubMed ID: 9753690
[TBL] [Abstract][Full Text] [Related]
4. The crystal structure of archaeal serine hydroxymethyltransferase reveals idiosyncratic features likely required to withstand high temperatures.
Angelucci F; Morea V; Angelaccio S; Saccoccia F; Contestabile R; Ilari A
Proteins; 2014 Dec; 82(12):3437-49. PubMed ID: 25257552
[TBL] [Abstract][Full Text] [Related]
5. Crystal structure at 2.4 A resolution of E. coli serine hydroxymethyltransferase in complex with glycine substrate and 5-formyl tetrahydrofolate.
Scarsdale JN; Radaev S; Kazanina G; Schirch V; Wright HT
J Mol Biol; 2000 Feb; 296(1):155-68. PubMed ID: 10656824
[TBL] [Abstract][Full Text] [Related]
6. Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming.
Paiardini A; Tramonti A; Schirch D; Guiducci G; di Salvo ML; Fiascarelli A; Giorgi A; Maras B; Cutruzzolà F; Contestabile R
Biochim Biophys Acta; 2016 Nov; 1864(11):1506-17. PubMed ID: 27530298
[TBL] [Abstract][Full Text] [Related]
7. The role of His-134, -147, and -150 residues in subunit assembly, cofactor binding, and catalysis of sheep liver cytosolic serine hydroxymethyltransferase.
Jagath JR; Sharma B; Rao NA; Savithri HS
J Biol Chem; 1997 Sep; 272(39):24355-62. PubMed ID: 9305893
[TBL] [Abstract][Full Text] [Related]
8. Crystal structure of rabbit cytosolic serine hydroxymethyltransferase at 2.8 A resolution: mechanistic implications.
Scarsdale JN; Kazanina G; Radaev S; Schirch V; Wright HT
Biochemistry; 1999 Jun; 38(26):8347-58. PubMed ID: 10387080
[TBL] [Abstract][Full Text] [Related]
9. Asp-89: a critical residue in maintaining the oligomeric structure of sheep liver cytosolic serine hydroxymethyltransferase.
Krishna Rao JV; Jagath JR; Sharma B; Appaji Rao N; Savithri HS
Biochem J; 1999 Oct; 343 Pt 1(Pt 1):257-63. PubMed ID: 10493937
[TBL] [Abstract][Full Text] [Related]
10. The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells.
Giardina G; Paone A; Tramonti A; Lucchi R; Marani M; Magnifico MC; Bouzidi A; Pontecorvi V; Guiducci G; Zamparelli C; Rinaldo S; Paiardini A; Contestabile R; Cutruzzolà F
FEBS J; 2018 Sep; 285(17):3238-3253. PubMed ID: 30035852
[TBL] [Abstract][Full Text] [Related]
11. Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties.
Tramonti A; Nardella C; di Salvo ML; Barile A; Cutruzzolà F; Contestabile R
Biochemistry; 2018 Dec; 57(51):6984-6996. PubMed ID: 30500180
[TBL] [Abstract][Full Text] [Related]
12. Disruption of distal interactions of Arg 262 and of substrate binding to Ser 52 affect catalysis of sheep liver cytosolic serine hydroxymethyltransferase.
Jala VR; Ambili M; Prakash V; Rao NA; Savithri HS
Indian J Biochem Biophys; 2003 Aug; 40(4):226-37. PubMed ID: 22900314
[TBL] [Abstract][Full Text] [Related]
13. Identification of amino acid residues, essential for maintaining the tetrameric structure of sheep liver cytosolic serine hydroxymethyltransferase, by targeted mutagenesis.
Jala VR; Appaji Rao N; Savithri HS
Biochem J; 2003 Feb; 369(Pt 3):469-76. PubMed ID: 12392447
[TBL] [Abstract][Full Text] [Related]
14. Interaction of sheep liver apo-serine hydroxymethyltransferase with pyridoxal-5'-phosphate: a physicochemical, kinetic, and thermodynamic study.
Brahatheeswaran B; Prakash V; Savithri HS; Rao NA
Arch Biochem Biophys; 1996 Jun; 330(2):363-72. PubMed ID: 8660666
[TBL] [Abstract][Full Text] [Related]
15. Distinct biochemical properties of human serine hydroxymethyltransferase compared with the Plasmodium enzyme: implications for selective inhibition.
Pinthong C; Maenpuen S; Amornwatcharapong W; Yuthavong Y; Leartsakulpanich U; Chaiyen P
FEBS J; 2014 Jun; 281(11):2570-83. PubMed ID: 24698160
[TBL] [Abstract][Full Text] [Related]
16. A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.
Marani M; Paone A; Fiascarelli A; Macone A; Gargano M; Rinaldo S; Giardina G; Pontecorvi V; Koes D; McDermott L; Yang T; Paiardini A; Contestabile R; Cutruzzolà F
Oncotarget; 2016 Jan; 7(4):4570-83. PubMed ID: 26717037
[TBL] [Abstract][Full Text] [Related]
17. Role of Lys-226 in the catalytic mechanism of Bacillus stearothermophilus serine hydroxymethyltransferase--crystal structure and kinetic studies.
Bhavani S; Trivedi V; Jala VR; Subramanya HS; Kaul P; Prakash V; Appaji Rao N; Savithri HS
Biochemistry; 2005 May; 44(18):6929-37. PubMed ID: 15865438
[TBL] [Abstract][Full Text] [Related]
18. The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase.
Florio R; Chiaraluce R; Consalvi V; Paiardini A; Catacchio B; Bossa F; Contestabile R
FEBS J; 2009 Jan; 276(1):132-43. PubMed ID: 19019081
[TBL] [Abstract][Full Text] [Related]
19. Serine hydroxymethyltransferase isoforms are differentially inhibited by leucovorin: characterization and comparison of recombinant zebrafish serine hydroxymethyltransferases.
Chang WN; Tsai JN; Chen BH; Huang HS; Fu TF
Drug Metab Dispos; 2007 Nov; 35(11):2127-37. PubMed ID: 17664250
[TBL] [Abstract][Full Text] [Related]
20. Metabolic control of BRISC-SHMT2 assembly regulates immune signalling.
Walden M; Tian L; Ross RL; Sykora UM; Byrne DP; Hesketh EL; Masandi SK; Cassel J; George R; Ault JR; El Oualid F; Pawłowski K; Salvino JM; Eyers PA; Ranson NA; Del Galdo F; Greenberg RA; Zeqiraj E
Nature; 2019 Jun; 570(7760):194-199. PubMed ID: 31142841
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
