383 related articles for article (PubMed ID: 25619930)
1. Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis.
Ikonomov OC; Sbrissa D; Venkatareddy M; Tisdale E; Garg P; Shisheva A
Biochim Biophys Acta; 2015 May; 1853(5):1240-50. PubMed ID: 25619930
[TBL] [Abstract][Full Text] [Related]
2. Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency.
Compton LM; Ikonomov OC; Sbrissa D; Garg P; Shisheva A
Am J Physiol Cell Physiol; 2016 Sep; 311(3):C366-77. PubMed ID: 27335171
[TBL] [Abstract][Full Text] [Related]
3. Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns(3,5)P2 but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane dilation.
Sbrissa D; Naisan G; Ikonomov OC; Shisheva A
PLoS One; 2018; 13(9):e0204532. PubMed ID: 30240452
[TBL] [Abstract][Full Text] [Related]
4. Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells.
Venkatareddy M; Verma R; Kalinowski A; Patel SR; Shisheva A; Garg P
J Am Soc Nephrol; 2016 Sep; 27(9):2702-19. PubMed ID: 26825532
[TBL] [Abstract][Full Text] [Related]
5. PIP5K1C phosphoinositide kinase deficiency distinguishes PIKFYVE-dependent cancer cells from non-malignant cells.
Roy A; Chakraborty AR; Nomanbhoy T; DePamphilis ML
Autophagy; 2023 Sep; 19(9):2464-2484. PubMed ID: 36803256
[TBL] [Abstract][Full Text] [Related]
6. PIK3C3/VPS34, the class III PtdIns 3-kinase, plays indispensable roles in the podocyte.
Chen JK
Autophagy; 2013 Jun; 9(6):923-4. PubMed ID: 23518611
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity.
Saffi GT; Wang CA; Mangialardi EM; Vacher J; Botelho RJ; Salmena L
J Biol Chem; 2022 Aug; 298(8):102187. PubMed ID: 35760104
[TBL] [Abstract][Full Text] [Related]
8. Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve-dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012).
Shisheva A; Sbrissa D; Ikonomov O
Bioessays; 2015 Mar; 37(3):267-77. PubMed ID: 25404370
[TBL] [Abstract][Full Text] [Related]
9. Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity.
Ikonomov OC; Sbrissa D; Mlak K; Kanzaki M; Pessin J; Shisheva A
J Biol Chem; 2002 Mar; 277(11):9206-11. PubMed ID: 11714711
[TBL] [Abstract][Full Text] [Related]
10. The class III phosphatidylinositol 3-kinase PIK3C3/VPS34 regulates endocytosis and autophagosome-autolysosome formation in podocytes.
Bechtel W; Helmstädter M; Balica J; Hartleben B; Schell C; Huber TB
Autophagy; 2013 Jul; 9(7):1097-9. PubMed ID: 23614954
[TBL] [Abstract][Full Text] [Related]
11. The PIKfyve-ArPIKfyve-Sac3 triad in human breast cancer: Functional link between elevated Sac3 phosphatase and enhanced proliferation of triple negative cell lines.
Ikonomov OC; Filios C; Sbrissa D; Chen X; Shisheva A
Biochem Biophys Res Commun; 2013 Oct; 440(2):342-7. PubMed ID: 24070605
[TBL] [Abstract][Full Text] [Related]
12. Sequential conversion of PtdIns3P to PtdIns(3,5)P
Rodgers SJ; Jones EI; Mitchell CA; McGrath MJ
Autophagy; 2023 Apr; 19(4):1365-1367. PubMed ID: 36103410
[TBL] [Abstract][Full Text] [Related]
13. Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve.
Ikonomov OC; Sbrissa D; Shisheva A
J Biol Chem; 2001 Jul; 276(28):26141-7. PubMed ID: 11285266
[TBL] [Abstract][Full Text] [Related]
14. Phosphatidylinositol 3 monophosphate metabolizing enzymes in blood platelet production and in thrombosis.
Bellio M; Caux M; Vauclard A; Chicanne G; Gratacap MP; Terrisse AD; Severin S; Payrastre B
Adv Biol Regul; 2020 Jan; 75():100664. PubMed ID: 31604685
[TBL] [Abstract][Full Text] [Related]
15. Insulin activation of vacuolar protein sorting 34 mediates localized phosphatidylinositol 3-phosphate production at lamellipodia and activation of mTOR/S6K1.
Hirsch DS; Shen Y; Dokmanovic M; Yu J; Mohan N; Elzarrad MK; Wu WJ
Cell Signal; 2014 Jun; 26(6):1258-68. PubMed ID: 24582588
[TBL] [Abstract][Full Text] [Related]
16. Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration.
Oppelt A; Lobert VH; Haglund K; Mackey AM; Rameh LE; Liestøl K; Schink KO; Pedersen NM; Wenzel EM; Haugsten EM; Brech A; Rusten TE; Stenmark H; Wesche J
EMBO Rep; 2013 Jan; 14(1):57-64. PubMed ID: 23154468
[TBL] [Abstract][Full Text] [Related]
17. Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes.
Giridharan SSP; Luo G; Rivero-Rios P; Steinfeld N; Tronchere H; Singla A; Burstein E; Billadeau DD; Sutton MA; Weisman LS
Elife; 2022 Jan; 11():. PubMed ID: 35040777
[TBL] [Abstract][Full Text] [Related]
18. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase.
Bago R; Malik N; Munson MJ; Prescott AR; Davies P; Sommer E; Shpiro N; Ward R; Cross D; Ganley IG; Alessi DR
Biochem J; 2014 Nov; 463(3):413-27. PubMed ID: 25177796
[TBL] [Abstract][Full Text] [Related]
19. Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636.
Sbrissa D; Ikonomov OC; Filios C; Delvecchio K; Shisheva A
Am J Physiol Cell Physiol; 2012 Aug; 303(4):C436-46. PubMed ID: 22621786
[TBL] [Abstract][Full Text] [Related]
20. Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis.
Devereaux K; Dall'Armi C; Alcazar-Roman A; Ogasawara Y; Zhou X; Wang F; Yamamoto A; De Camilli P; Di Paolo G
PLoS One; 2013; 8(10):e76405. PubMed ID: 24098492
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
