BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 25631326)

  • 1. Evaluation of the anti-tumor effects of lactate dehydrogenase inhibitor galloflavin in endometrial cancer cells.
    Han X; Sheng X; Jones HM; Jackson AL; Kilgore J; Stine JE; Schointuch MN; Zhou C; Bae-Jump VL
    J Hematol Oncol; 2015 Jan; 8():2. PubMed ID: 25631326
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase.
    Manerba M; Vettraino M; Fiume L; Di Stefano G; Sartini A; Giacomini E; Buonfiglio R; Roberti M; Recanatini M
    ChemMedChem; 2012 Feb; 7(2):311-7. PubMed ID: 22052811
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Therapeutic Strategies Toward Lactate Dehydrogenase Within the Tumor Microenvironment of Pancreatic Cancer.
    Moir JAG; Long A; Haugk B; French JJ; Charnley RM; Manas DM; Wedge SR; Mann J; Robinson SM; White SA
    Pancreas; 2020; 49(10):1364-1371. PubMed ID: 33122526
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways.
    Farabegoli F; Vettraino M; Manerba M; Fiume L; Roberti M; Di Stefano G
    Eur J Pharm Sci; 2012 Nov; 47(4):729-38. PubMed ID: 22954722
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes.
    Manerba M; Di Ianni L; Fiume L; Roberti M; Recanatini M; Di Stefano G
    Eur J Pharm Sci; 2015 Jul; 74():95-102. PubMed ID: 25930121
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1.
    Vettraino M; Manerba M; Govoni M; Di Stefano G
    Anticancer Drugs; 2013 Sep; 24(8):862-70. PubMed ID: 23797802
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A.
    Rupiani S; Guidotti L; Manerba M; Di Ianni L; Giacomini E; Falchi F; Di Stefano G; Roberti M; Recanatini M
    Org Biomol Chem; 2016 Nov; 14(46):10981-10987. PubMed ID: 27827510
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impairment of aerobic glycolysis by inhibitors of lactic dehydrogenase hinders the growth of human hepatocellular carcinoma cell lines.
    Fiume L; Manerba M; Vettraino M; Di Stefano G
    Pharmacology; 2010; 86(3):157-62. PubMed ID: 20699632
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Galloflavin prevents the binding of lactate dehydrogenase A to single stranded DNA and inhibits RNA synthesis in cultured cells.
    Fiume L; Vettraino M; Carnicelli D; Arfilli V; Di Stefano G; Brigotti M
    Biochem Biophys Res Commun; 2013 Jan; 430(2):466-9. PubMed ID: 23237800
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glucose promotes cell proliferation, glucose uptake and invasion in endometrial cancer cells via AMPK/mTOR/S6 and MAPK signaling.
    Han J; Zhang L; Guo H; Wysham WZ; Roque DR; Willson AK; Sheng X; Zhou C; Bae-Jump VL
    Gynecol Oncol; 2015 Sep; 138(3):668-75. PubMed ID: 26135947
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma.
    Yeung C; Gibson AE; Issaq SH; Oshima N; Baumgart JT; Edessa LD; Rai G; Urban DJ; Johnson MS; Benavides GA; Squadrito GL; Yohe ME; Lei H; Eldridge S; Hamre J; Dowdy T; Ruiz-Rodado V; Lita A; Mendoza A; Shern JF; Larion M; Helman LJ; Stott GM; Krishna MC; Hall MD; Darley-Usmar V; Neckers LM; Heske CM
    Cancer Res; 2019 Oct; 79(19):5060-5073. PubMed ID: 31431459
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pyruvate dehydrogenase complex and lactate dehydrogenase are targets for therapy of acute liver failure.
    Ferriero R; Nusco E; De Cegli R; Carissimo A; Manco G; Brunetti-Pierri N
    J Hepatol; 2018 Aug; 69(2):325-335. PubMed ID: 29580866
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells.
    Manerba M; Di Ianni L; Govoni M; Roberti M; Recanatini M; Di Stefano G
    Eur J Pharm Sci; 2017 Jan; 96():37-44. PubMed ID: 27622920
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bioactivity-guided identification and cell signaling technology to delineate the lactate dehydrogenase A inhibition effects of Spatholobus suberectus on breast cancer.
    Wang Z; Wang D; Han S; Wang N; Mo F; Loo TY; Shen J; Huang H; Chen J
    PLoS One; 2013; 8(2):e56631. PubMed ID: 23457597
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment.
    Balboni A; Govoni M; Rossi V; Roberti M; Cavalli A; Di Stefano G; Manerba M
    Biochim Biophys Acta Gen Subj; 2021 Jan; 1865(1):129760. PubMed ID: 33035602
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of the suppression of lactate dehydrogenase A on the growth and invasion of human gastric cancer cells.
    Liu X; Yang Z; Chen Z; Chen R; Zhao D; Zhou Y; Qiao L
    Oncol Rep; 2015 Jan; 33(1):157-62. PubMed ID: 25394466
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Galloflavin Plus Metformin Treatment Impairs Pancreatic Cancer Cells.
    Wendt EHU; Schoenrogge M; Vollmar B; Zechner D
    Anticancer Res; 2020 Jan; 40(1):153-160. PubMed ID: 31892563
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Symmetric molecules with 1,4-triazole moieties as potent inhibitors of tumour-associated lactate dehydrogenase-A.
    Altamimi AS; Alafeefy AM; Balode A; Vozny I; Pustenko A; El Shikh ME; Alasmary FAS; Abdel-Gawad SA; Žalubovskis R
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):147-150. PubMed ID: 29199484
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Real-time monitoring of cancer cell metabolism and effects of an anticancer agent using 2D in-cell NMR spectroscopy.
    Wen H; An YJ; Xu WJ; Kang KW; Park S
    Angew Chem Int Ed Engl; 2015 Apr; 54(18):5374-7. PubMed ID: 25752301
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.
    Chaube B; Malvi P; Singh SV; Mohammad N; Meena AS; Bhat MK
    Oncotarget; 2015 Nov; 6(35):37281-99. PubMed ID: 26484566
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.