BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 25633294)

  • 1. Angelman syndrome-associated ubiquitin ligase UBE3A/E6AP mutants interfere with the proteolytic activity of the proteasome.
    Tomaić V; Banks L
    Cell Death Dis; 2015 Jan; 6(1):e1625. PubMed ID: 25633294
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Angelman syndrome-associated point mutations in the Zn
    Kühnle S; Martínez-Noël G; Leclere F; Hayes SD; Harper JW; Howley PM
    J Biol Chem; 2018 Nov; 293(47):18387-18399. PubMed ID: 30257870
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A proteasomal partner goes missing in Angelman syndrome.
    Huibregtse JM
    J Biol Chem; 2018 Nov; 293(47):18400-18401. PubMed ID: 30470726
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of Small-Molecule Activators of the Ubiquitin Ligase E6AP/UBE3A and Angelman Syndrome-Derived E6AP/UBE3A Variants.
    Offensperger F; Müller F; Jansen J; Hammler D; Götz KH; Marx A; Sirois CL; Chamberlain SJ; Stengel F; Scheffner M
    Cell Chem Biol; 2020 Dec; 27(12):1510-1520.e6. PubMed ID: 32966807
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes.
    Martínez-Noël G; Galligan JT; Sowa ME; Arndt V; Overton TM; Harper JW; Howley PM
    Mol Cell Biol; 2012 Aug; 32(15):3095-106. PubMed ID: 22645313
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cobalamins Function as Allosteric Activators of an Angelman Syndrome-Associated UBE3A/E6AP Variant.
    Müller F; Jansen J; Offensperger F; Eichbichler D; Stengel F; Scheffner M
    Chembiochem; 2024 May; 25(10):e202400184. PubMed ID: 38573110
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An Angelman syndrome substitution in the HECT E3 ubiquitin ligase C-terminal Lobe of E6AP affects protein stability and activity.
    Beasley SA; Kellum CE; Orlomoski RJ; Idrizi F; Spratt DE
    PLoS One; 2020; 15(7):e0235925. PubMed ID: 32639967
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome.
    Ramirez J; Lectez B; Osinalde N; Sivá M; Elu N; Aloria K; Procházková M; Perez C; Martínez-Hernández J; Barrio R; Šašková KG; Arizmendi JM; Mayor U
    Hum Mol Genet; 2018 Jun; 27(11):1955-1971. PubMed ID: 29788202
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein.
    Cooper EM; Hudson AW; Amos J; Wagstaff J; Howley PM
    J Biol Chem; 2004 Sep; 279(39):41208-17. PubMed ID: 15263005
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome.
    Yi JJ; Paranjape SR; Walker MP; Choudhury R; Wolter JM; Fragola G; Emanuele MJ; Major MB; Zylka MJ
    J Biol Chem; 2017 Jul; 292(30):12503-12515. PubMed ID: 28559284
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human disorders of ubiquitination and proteasomal degradation.
    Jiang YH; Beaudet AL
    Curr Opin Pediatr; 2004 Aug; 16(4):419-26. PubMed ID: 15273504
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Loss of nuclear UBE3A activity is the predominant cause of Angelman syndrome in individuals carrying UBE3A missense mutations.
    Bossuyt SNV; Punt AM; de Graaf IJ; van den Burg J; Williams MG; Heussler H; Elgersma Y; Distel B
    Hum Mol Genet; 2021 Apr; 30(6):430-442. PubMed ID: 33607653
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Angelman syndrome scientific symposium on the structure and function of UBE3A/E6AP.
    Williams C
    J Child Neurol; 2009 Jul; 24(7):904-8. PubMed ID: 19617463
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epigenetic regulation of UBE3A and roles in human neurodevelopmental disorders.
    LaSalle JM; Reiter LT; Chamberlain SJ
    Epigenomics; 2015 Oct; 7(7):1213-28. PubMed ID: 26585570
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology.
    Pandya NJ; Wang C; Costa V; Lopatta P; Meier S; Zampeta FI; Punt AM; Mientjes E; Grossen P; Distler T; Tzouros M; Martí Y; Banfai B; Patsch C; Rasmussen S; Hoener M; Berrera M; Kremer T; Dunkley T; Ebeling M; Distel B; Elgersma Y; Jagasia R
    Cell Rep Med; 2021 Aug; 2(8):100360. PubMed ID: 34467244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.
    Lee SY; Ramirez J; Franco M; Lectez B; Gonzalez M; Barrio R; Mayor U
    Cell Mol Life Sci; 2014 Jul; 71(14):2747-58. PubMed ID: 24292889
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of ubiquitin and the HPV E6 oncoprotein in E6AP-mediated ubiquitination.
    Mortensen F; Schneider D; Barbic T; Sladewska-Marquardt A; Kühnle S; Marx A; Scheffner M
    Proc Natl Acad Sci U S A; 2015 Aug; 112(32):9872-7. PubMed ID: 26216987
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Network Analysis of UBE3A/E6AP-Associated Proteins Provides Connections to Several Distinct Cellular Processes.
    Martínez-Noël G; Luck K; Kühnle S; Desbuleux A; Szajner P; Galligan JT; Rodriguez D; Zheng L; Boyland K; Leclere F; Zhong Q; Hill DE; Vidal M; Howley PM
    J Mol Biol; 2018 Mar; 430(7):1024-1050. PubMed ID: 29426014
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel UBE3A sequence variant identified in eight related individuals with neurodevelopmental delay, results in a phenotype which does not match the clinical criteria of Angelman syndrome.
    Geerts-Haages A; Bossuyt SNV; den Besten I; Bruggenwirth H; van der Burgt I; Yntema HG; Punt AM; Brooks A; Elgersma Y; Distel B; Valstar M
    Mol Genet Genomic Med; 2020 Nov; 8(11):e1481. PubMed ID: 32889787
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HIV-1 Impairment via UBE3A and HIV-1 Nef Interactions Utilizing the Ubiquitin Proteasome System.
    Pyeon D; Rojas VK; Price L; Kim S; Meharvan S; Park IW
    Viruses; 2019 Nov; 11(12):. PubMed ID: 31783587
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.