634 related articles for article (PubMed ID: 25637943)
21. Assessment of renal injury in vivo.
Emeigh Hart SG
J Pharmacol Toxicol Methods; 2005; 52(1):30-45. PubMed ID: 15953738
[TBL] [Abstract][Full Text] [Related]
22. High dose selection in general toxicity studies for drug development: A pharmaceutical industry perspective.
Buckley LA; Dorato MA
Regul Toxicol Pharmacol; 2009 Aug; 54(3):301-7. PubMed ID: 19477212
[TBL] [Abstract][Full Text] [Related]
23. Safety pharmacology--current and emerging concepts.
Hamdam J; Sethu S; Smith T; Alfirevic A; Alhaidari M; Atkinson J; Ayala M; Box H; Cross M; Delaunois A; Dermody A; Govindappa K; Guillon JM; Jenkins R; Kenna G; Lemmer B; Meecham K; Olayanju A; Pestel S; Rothfuss A; Sidaway J; Sison-Young R; Smith E; Stebbings R; Tingle Y; Valentin JP; Williams A; Williams D; Park K; Goldring C
Toxicol Appl Pharmacol; 2013 Dec; 273(2):229-41. PubMed ID: 23732082
[TBL] [Abstract][Full Text] [Related]
24. Preclinical pharmacokinetic/pharmacodynamic modeling and simulation in the pharmaceutical industry: an IQ consortium survey examining the current landscape.
Schuck E; Bohnert T; Chakravarty A; Damian-Iordache V; Gibson C; Hsu CP; Heimbach T; Krishnatry AS; Liederer BM; Lin J; Maurer T; Mettetal JT; Mudra DR; Nijsen MJ; Raybon J; Schroeder P; Schuck V; Suryawanshi S; Su Y; Trapa P; Tsai A; Vakilynejad M; Wang S; Wong H
AAPS J; 2015 Mar; 17(2):462-73. PubMed ID: 25630504
[TBL] [Abstract][Full Text] [Related]
25. Zebrafish based assays for the assessment of cardiac, visual and gut function--potential safety screens for early drug discovery.
Berghmans S; Butler P; Goldsmith P; Waldron G; Gardner I; Golder Z; Richards FM; Kimber G; Roach A; Alderton W; Fleming A
J Pharmacol Toxicol Methods; 2008; 58(1):59-68. PubMed ID: 18585469
[TBL] [Abstract][Full Text] [Related]
26. The Use of Minipigs for Preclinical Safety Assessment by the Pharmaceutical Industry: Results of an IQ DruSafe Minipig Survey.
Colleton C; Brewster D; Chester A; Clarke DO; Heining P; Olaharski A; Graziano M
Toxicol Pathol; 2016 Apr; 44(3):458-66. PubMed ID: 27006130
[TBL] [Abstract][Full Text] [Related]
27. An Industry Survey With Focus on Cardiovascular Safety Pharmacology Study Design and Data Interpretation.
Authier S; Abernathy MM; Correll K; Chui RW; Dalton J; Foley CM; Friedrichs GS; Koerner JE; Kallman MJ; Pannirselvam M; Redfern WS; Urmaliya V; Valentin JP; Wisialowski T; Zabka TS; Pugsley MK
Int J Toxicol; 2020; 39(4):274-293. PubMed ID: 32406289
[TBL] [Abstract][Full Text] [Related]
28. NTP Toxicology and Carcinogenesis Studies of 1-Amino-2,4-Dibromoanthraquinone (CAS No. 81-49-2) in F344/N Rats and B6C3F1 Mice (Feed Studies).
National Toxicology Program
Natl Toxicol Program Tech Rep Ser; 1996 Aug; 383():1-370. PubMed ID: 12692653
[TBL] [Abstract][Full Text] [Related]
29. Drug safety Africa: An overview of safety pharmacology & toxicology in South Africa.
Guth BD; Grobler AF; Frazier KS; Greiter-Wilke A; Herzyk D; Hough TA; Khan AA; Markert M; Smith JD; Svenson KL; Wells S; Pugsley MK
J Pharmacol Toxicol Methods; 2019; 98():106579. PubMed ID: 31085319
[TBL] [Abstract][Full Text] [Related]
30. A predictive index of biomarkers for ictogenesis from tier I safety pharmacology testing that may warrant tier II EEG studies.
Gauvin DV; Zimmermann ZJ; Yoder J; Harter M; Holdsworth D; Kilgus Q; May J; Dalton J; Baird TJ
J Pharmacol Toxicol Methods; 2018; 94(Pt 1):50-63. PubMed ID: 29751085
[TBL] [Abstract][Full Text] [Related]
31. Reducing attrition in drug development: smart loading preclinical safety assessment.
Roberts RA; Kavanagh SL; Mellor HR; Pollard CE; Robinson S; Platz SJ
Drug Discov Today; 2014 Mar; 19(3):341-7. PubMed ID: 24269835
[TBL] [Abstract][Full Text] [Related]
32. Current Trends of Practices in Nonclinical Toxicology: An Industry Survey.
Authier S; Brock WJ; Halpern W; Harris SN; Jones D; McGovern T; McGovern PD; Pugsley MK
Int J Toxicol; 2021 Dec; 40(6):487-505. PubMed ID: 34569357
[TBL] [Abstract][Full Text] [Related]
33. A framework to assess the translation of safety pharmacology data to humans.
Valentin JP; Bialecki R; Ewart L; Hammond T; Leishmann D; Lindgren S; Martinez V; Pollard C; Redfern W; Wallis R
J Pharmacol Toxicol Methods; 2009; 60(2):152-8. PubMed ID: 19616110
[TBL] [Abstract][Full Text] [Related]
34. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
EFSA GMO Panel Working Group on Animal Feeding Trials
Food Chem Toxicol; 2008 Mar; 46 Suppl 1():S2-70. PubMed ID: 18328408
[TBL] [Abstract][Full Text] [Related]
35. The use of emerging safety biomarkers in nonclinical and clinical safety assessment - The current and future state: An IQ DruSafe industry survey.
Zabka TS; Burkhardt J; Reagan WJ; Gautier JC; Glaab WE; Guffroy M; Harding J; Brees D; McDuffie E; Ramaiah L; Schultze AE; Smith JD; Wolfreys A; Dalmas DA
Regul Toxicol Pharmacol; 2021 Mar; 120():104857. PubMed ID: 33387566
[TBL] [Abstract][Full Text] [Related]
36. Exploratory toxicology as an integrated part of drug discovery. Part II: Screening strategies.
Hornberg JJ; Laursen M; Brenden N; Persson M; Thougaard AV; Toft DB; Mow T
Drug Discov Today; 2014 Aug; 19(8):1137-44. PubMed ID: 24374152
[TBL] [Abstract][Full Text] [Related]
37. Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach.
Ebbels TM; Keun HC; Beckonert OP; Bollard ME; Lindon JC; Holmes E; Nicholson JK
J Proteome Res; 2007 Nov; 6(11):4407-22. PubMed ID: 17915905
[TBL] [Abstract][Full Text] [Related]
38. Innovation in safety pharmacology testing.
Pugsley MK; Towart R; Authier S; Gallacher DJ; Curtis MJ
J Pharmacol Toxicol Methods; 2011; 64(1):1-6. PubMed ID: 21640842
[TBL] [Abstract][Full Text] [Related]
39. The application of in vitro methods to safety pharmacology.
Wakefield ID; Pollard C; Redfern WS; Hammond TG; Valentin JP
Fundam Clin Pharmacol; 2002 Jun; 16(3):209-18. PubMed ID: 12165068
[TBL] [Abstract][Full Text] [Related]
40. Pharmaceutical industry perspective on combination toxicity studies: Results from an intra-industry survey conducted by IQ DruSafe Leadership Group.
Birkebak J; Buckley LA; Dambach D; Musvasva E; Price K; Ralston S; Sacaan A
Regul Toxicol Pharmacol; 2019 Mar; 102():40-46. PubMed ID: 30576687
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]