327 related articles for article (PubMed ID: 25645022)
1. Structural insight into mechanisms for dynamic regulation of PKM2.
Wang P; Sun C; Zhu T; Xu Y
Protein Cell; 2015 Apr; 6(4):275-287. PubMed ID: 25645022
[TBL] [Abstract][Full Text] [Related]
2. Structural basis of PKM2 regulation.
Yang W
Protein Cell; 2015 Apr; 6(4):238-40. PubMed ID: 25773278
[No Abstract] [Full Text] [Related]
3. Structural Investigation of a Dimeric Variant of Pyruvate Kinase Muscle Isoform 2.
Srivastava D; Razzaghi M; Henzl MT; Dey M
Biochemistry; 2017 Dec; 56(50):6517-6520. PubMed ID: 29182273
[TBL] [Abstract][Full Text] [Related]
4. Cancer-associated mutations in human pyruvate kinase M2 impair enzyme activity.
Liu VM; Howell AJ; Hosios AM; Li Z; Israelsen WJ; Vander Heiden MG
FEBS Lett; 2020 Feb; 594(4):646-664. PubMed ID: 31642061
[TBL] [Abstract][Full Text] [Related]
5. An engineered photoswitchable mammalian pyruvate kinase.
Gehrig S; Macpherson JA; Driscoll PC; Symon A; Martin SR; MacRae JI; Kleinjung J; Fraternali F; Anastasiou D
FEBS J; 2017 Sep; 284(18):2955-2980. PubMed ID: 28715126
[TBL] [Abstract][Full Text] [Related]
6. Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation.
Macpherson JA; Theisen A; Masino L; Fets L; Driscoll PC; Encheva V; Snijders AP; Martin SR; Kleinjung J; Barran PE; Fraternali F; Anastasiou D
Elife; 2019 Jul; 8():. PubMed ID: 31264961
[TBL] [Abstract][Full Text] [Related]
7. Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2.
Srivastava D; Nandi S; Dey M
Biochemistry; 2019 Sep; 58(35):3669-3682. PubMed ID: 31386812
[TBL] [Abstract][Full Text] [Related]
8. Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation.
Chen TJ; Wang HJ; Liu JS; Cheng HH; Hsu SC; Wu MC; Lu CH; Wu YF; Wu JW; Liu YY; Kung HJ; Wang WC
Commun Biol; 2019; 2():105. PubMed ID: 30911680
[TBL] [Abstract][Full Text] [Related]
9. The cysteine residue at 424th of pyruvate kinase M2 is crucial for tetramerization and responsiveness to oxidative stress.
Masaki S; Hashimoto K; Kihara D; Tsuzuki C; Kataoka N; Suzuki K
Biochem Biophys Res Commun; 2020 Jun; 526(4):973-977. PubMed ID: 32295714
[TBL] [Abstract][Full Text] [Related]
10. Glycolytic reprogramming in cancer cells: PKM2 dimer predominance induced by pulsatile PFK-1 activity.
Shi X; You L; Luo RY
Phys Biol; 2019 Sep; 16(6):066007. PubMed ID: 31469100
[TBL] [Abstract][Full Text] [Related]
11. Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation.
Nandi S; Razzaghi M; Srivastava D; Dey M
J Biol Chem; 2020 Dec; 295(51):17425-17440. PubMed ID: 33453989
[TBL] [Abstract][Full Text] [Related]
12. Biochemical and structural insights into how amino acids regulate pyruvate kinase muscle isoform 2.
Nandi S; Dey M
J Biol Chem; 2020 Apr; 295(16):5390-5403. PubMed ID: 32144209
[TBL] [Abstract][Full Text] [Related]
13. The role of PKM2 in cancer progression and its structural and biological basis.
Wu B; Liang Z; Lan H; Teng X; Wang C
J Physiol Biochem; 2024 May; 80(2):261-275. PubMed ID: 38329688
[TBL] [Abstract][Full Text] [Related]
14. Moderate DNA damage promotes metabolic flux into PPP via PKM2 Y-105 phosphorylation: a feature that favours cancer cells.
Kumar B; Bamezai RN
Mol Biol Rep; 2015 Aug; 42(8):1317-21. PubMed ID: 25840825
[TBL] [Abstract][Full Text] [Related]
15. Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization.
Lv L; Xu YP; Zhao D; Li FL; Wang W; Sasaki N; Jiang Y; Zhou X; Li TT; Guan KL; Lei QY; Xiong Y
Mol Cell; 2013 Nov; 52(3):340-52. PubMed ID: 24120661
[TBL] [Abstract][Full Text] [Related]
16. SIRT2-Mediated Deacetylation and Tetramerization of Pyruvate Kinase Directs Glycolysis and Tumor Growth.
Park SH; Ozden O; Liu G; Song HY; Zhu Y; Yan Y; Zou X; Kang HJ; Jiang H; Principe DR; Cha YI; Roh M; Vassilopoulos A; Gius D
Cancer Res; 2016 Jul; 76(13):3802-12. PubMed ID: 27197174
[TBL] [Abstract][Full Text] [Related]
17. Native Mass Spectrometry Gives Insight into the Allosteric Binding Mechanism of M2 Pyruvate Kinase to Fructose-1,6-Bisphosphate.
Gavriilidou AFM; Holding FP; Mayer D; Coyle JE; Veprintsev DB; Zenobi R
Biochemistry; 2018 Mar; 57(11):1685-1689. PubMed ID: 29499117
[TBL] [Abstract][Full Text] [Related]
18. Oncogenic Kinase-Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem-like Cells.
Zhou Z; Li M; Zhang L; Zhao H; Şahin Ö; Chen J; Zhao JJ; Songyang Z; Yu D
Cancer Res; 2018 May; 78(9):2248-2261. PubMed ID: 29440169
[TBL] [Abstract][Full Text] [Related]
19. Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia.
Li J; Li S; Guo J; Li Q; Long J; Ma C; Ding Y; Yan C; Li L; Wu Z; Zhu H; Li KK; Wen L; Zhang Q; Xue Q; Zhao C; Liu N; Ivanov I; Luo M; Xi R; Long H; Wang PG; Chen Y
J Med Chem; 2018 May; 61(9):4155-4164. PubMed ID: 29641204
[TBL] [Abstract][Full Text] [Related]
20. Lack of Evidence for PKM2 Protein Kinase Activity.
Hosios AM; Fiske BP; Gui DY; Vander Heiden MG
Mol Cell; 2015 Sep; 59(5):850-7. PubMed ID: 26300261
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]