BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 25656284)

  • 21. Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of Lapatinib.
    Towles JK; Clark RN; Wahlin MD; Uttamsingh V; Rettie AE; Jackson KD
    Drug Metab Dispos; 2016 Oct; 44(10):1584-97. PubMed ID: 27450182
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Effect of Piperine on the Metabolism and Pharmacokinetics of Carbamazepine in Healthy Volunteers.
    Bedada SK; Appani R; Boga PK
    Drug Res (Stuttg); 2017 Jan; 67(1):46-51. PubMed ID: 27776366
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The first-line antiepileptic drug carbamazepine: Reaction with biologically relevant free radicals.
    Martins IL; Nunes J; Charneira C; Morello J; Pereira SA; Telo JP; Marques MM; Antunes AMM
    Free Radic Biol Med; 2018 Dec; 129():559-568. PubMed ID: 30342189
    [TBL] [Abstract][Full Text] [Related]  

  • 24. An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics.
    Vignati L; Turlizzi E; Monaci S; Grossi P; Kanter Rd; Monshouwer M
    Toxicology; 2005 Dec; 216(2-3):154-67. PubMed ID: 16169652
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Tofacitinib Is a Mechanism-Based Inactivator of Cytochrome P450 3A4.
    Guo X; Li W; Li Q; Chen Y; Zhao G; Peng Y; Zheng J
    Chem Res Toxicol; 2019 Sep; 32(9):1791-1800. PubMed ID: 31414593
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Pathways of carbamazepine bioactivation in vitro. III. The role of human cytochrome P450 enzymes in the formation of 2,3-dihydroxycarbamazepine.
    Pearce RE; Lu W; Wang Y; Uetrecht JP; Correia MA; Leeder JS
    Drug Metab Dispos; 2008 Aug; 36(8):1637-49. PubMed ID: 18463198
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Hepatocellular toxicity of clopidogrel: mechanisms and risk factors.
    Zahno A; Bouitbir J; Maseneni S; Lindinger PW; Brecht K; Krähenbühl S
    Free Radic Biol Med; 2013 Dec; 65():208-216. PubMed ID: 23770199
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics.
    Grimm SW; Richtand NM; Winter HR; Stams KR; Reele SB
    Br J Clin Pharmacol; 2006 Jan; 61(1):58-69. PubMed ID: 16390352
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.
    Ball SE; Ahern D; Scatina J; Kao J
    Br J Clin Pharmacol; 1997 Jun; 43(6):619-26. PubMed ID: 9205822
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Effects of EPHX1 and CYP3A4*22 genetic polymorphisms on carbamazepine metabolism and drug response among Tunisian epileptic patients.
    Chbili C; Fathallah N; Laouani A; Nouira M; Hassine A; Ben Amor S; Ben Ammou S; Ben Salem C; Saguem S
    J Neurogenet; 2016 Mar; 30(1):16-21. PubMed ID: 27276192
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Evaluation of Cytochrome P450 (CYP) 3A4-Based Interactions of Levomilnacipran with Ketoconazole, Carbamazepine or Alprazolam in Healthy Subjects.
    Chen L; Boinpally R; Gad N; Greenberg WM; Wangsa J; Periclou A; Ghahramani P
    Clin Drug Investig; 2015 Oct; 35(10):601-12. PubMed ID: 26315684
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Effects of sinapic acid on hepatic cytochrome P450 3A2, 2C11, and intestinal P-glycoprotein on the pharmacokinetics of oral carbamazepine in rats: Potential food/herb-drug interaction.
    Raish M; Ahmad A; Ansari MA; Alkharfy KM; Ahad A; Al-Jenoobi FI; Al-Mohizea AM; Khan A; Ali N
    Epilepsy Res; 2019 Jul; 153():14-18. PubMed ID: 30927680
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Nortriptyline E-10-hydroxylation in vitro is mediated by human CYP2D6 (high affinity) and CYP3A4 (low affinity): implications for interactions with enzyme-inducing drugs.
    Venkatakrishnan K; von Moltke LL; Greenblatt DJ
    J Clin Pharmacol; 1999 Jun; 39(6):567-77. PubMed ID: 10354960
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Response to sertraline and antiepileptic drugs in pentylenetetrazole kindling in rats.
    Hussain M; Rashid H; Katyal J
    Brain Res; 2021 Nov; 1771():147645. PubMed ID: 34480951
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Saikosaponins and the deglycosylated metabolites exert liver meridian guiding effect through PXR/CYP3A4 inhibition.
    Liu Q; Xue Y; Liu J; Ren S; Xu J; Yang J; Xing Y; Zhang Z; Song R
    J Ethnopharmacol; 2021 Oct; 279():114344. PubMed ID: 34147617
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Concurrent cooperativity and substrate inhibition in the epoxidation of carbamazepine by cytochrome P450 3A4 active site mutants inspired by molecular dynamics simulations.
    Müller CS; Knehans T; Davydov DR; Bounds PL; von Mandach U; Halpert JR; Caflisch A; Koppenol WH
    Biochemistry; 2015 Jan; 54(3):711-21. PubMed ID: 25545162
    [TBL] [Abstract][Full Text] [Related]  

  • 37. In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.
    Utkarsh D; Loretz C; Li AP
    Chem Biol Interact; 2016 Aug; 255():12-22. PubMed ID: 26718876
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Development of a highly reproducible system to evaluate inhibition of cytochrome P450 3A4 activity by natural medicines.
    Sato Y; Sasaki T; Takahashi S; Kumagai T; Nagata K
    J Pharm Pharm Sci; 2015; 18(4):316-27. PubMed ID: 26626238
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam.
    van Waterschoot RA; Rooswinkel RW; Sparidans RW; van Herwaarden AE; Beijnen JH; Schinkel AH
    Drug Metab Dispos; 2009 Dec; 37(12):2305-13. PubMed ID: 19752211
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Elevation of plasma carbamazepine concentrations by ketoconazole in patients with epilepsy.
    Spina E; Arena D; Scordo MG; Fazio A; Pisani F; Perucca E
    Ther Drug Monit; 1997 Oct; 19(5):535-8. PubMed ID: 9357097
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.