119 related articles for article (PubMed ID: 25658964)
1. Synthesis and structure-activity relationship study of a new series of selective σ(1) receptor ligands for the treatment of pain: 4-aminotriazoles.
Díaz JL; Christmann U; Fernández A; Torrens A; Port A; Pascual R; Álvarez I; Burgueño J; Monroy X; Montero A; Balada A; Vela JM; Almansa C
J Med Chem; 2015 Mar; 58(5):2441-51. PubMed ID: 25658964
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain.
Lan Y; Chen Y; Cao X; Zhang J; Wang J; Xu X; Qiu Y; Zhang T; Liu X; Liu BF; Zhang G
J Med Chem; 2014 Dec; 57(24):10404-23. PubMed ID: 25420090
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of novel 6,7-dihydro-5H-cyclopenta[d]pyrimidine and 5,6,7,8-tetrahydroquinazoline derivatives as sigma-1 (σ1) receptor antagonists for the treatment of pain.
Lan Y; Songyang Y; Zhang L; Peng Y; Song J
Bioorg Med Chem Lett; 2016 Apr; 26(8):2051-6. PubMed ID: 26947609
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of a novel sigma-1 receptor antagonist based on 3,4-dihydro-2(1H)-quinolinone scaffold as a potential analgesic.
Lan Y; Chen Y; Xu X; Qiu Y; Liu S; Liu X; Liu BF; Zhang G
Eur J Med Chem; 2014 May; 79():216-30. PubMed ID: 24735647
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological evaluation of the 1-arylpyrazole class of σ(1) receptor antagonists: identification of 4-{2-[5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine (S1RA, E-52862).
Díaz JL; Cuberes R; Berrocal J; Contijoch M; Christmann U; Fernández A; Port A; Holenz J; Buschmann H; Laggner C; Serafini MT; Burgueño J; Zamanillo D; Merlos M; Vela JM; Almansa C
J Med Chem; 2012 Oct; 55(19):8211-24. PubMed ID: 22784008
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of a new series of hexahydro-2H-pyrano[3,2-c]quinolines as novel selective σ1 receptor ligands.
Díaz JL; Christmann U; Fernández A; Luengo M; Bordas M; Enrech R; Carro M; Pascual R; Burgueño J; Merlos M; Benet-Buchholz J; Cerón-Bertran J; Ramírez J; Reinoso RF; Fernández de Henestrosa AR; Vela JM; Almansa C
J Med Chem; 2013 May; 56(9):3656-65. PubMed ID: 23560650
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and pharmacological evaluation of a potent and selective σ1 receptor antagonist with high antiallodynic activity.
Utech T; Köhler J; Buschmann H; Holenz J; Vela JM; Wünsch B
Arch Pharm (Weinheim); 2011 Jul; 344(7):415-21. PubMed ID: 21598296
[TBL] [Abstract][Full Text] [Related]
8. Novel highly potent and selective sigma 1 receptor antagonists related to spipethiane.
Piergentili A; Amantini C; Del Bello F; Giannella M; Mattioli L; Palmery M; Perfumi M; Pigini M; Santoni G; Tucci P; Zotti M; Quaglia W
J Med Chem; 2010 Feb; 53(3):1261-9. PubMed ID: 20067271
[TBL] [Abstract][Full Text] [Related]
9. Pharmacological and metabolic characterisation of the potent sigma1 receptor ligand 1'-benzyl-3-methoxy-3H-spiro[[2]benzofuran-1,4'-piperidine].
Wiese C; Grosse Maestrup E; Schepmann D; Vela JM; Holenz J; Buschmann H; Wünsch B
J Pharm Pharmacol; 2009 May; 61(5):631-40. PubMed ID: 19406002
[TBL] [Abstract][Full Text] [Related]
10. Development of New Benzylpiperazine Derivatives as σ
Romeo G; Bonanno F; Wilson LL; Arena E; Modica MN; Pittalà V; Salerno L; Prezzavento O; McLaughlin JP; Intagliata S
ACS Chem Neurosci; 2021 Jun; 12(11):2003-2012. PubMed ID: 34019387
[TBL] [Abstract][Full Text] [Related]
11. Tricyclic Triazoles as σ
Díaz JL; Cuevas F; Oliva AI; Font D; Sarmentero MÁ; Álvarez-Bercedo P; López-Valbuena JM; Pericàs MA; Enrech R; Montero A; Yeste S; Vidal-Torres A; Álvarez I; Pérez P; Cendán CM; Cobos EJ; Vela JM; Almansa C
J Med Chem; 2021 Apr; 64(8):5157-5170. PubMed ID: 33826322
[TBL] [Abstract][Full Text] [Related]
12. Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives.
Franchini S; Battisti UM; Prandi A; Tait A; Borsari C; Cichero E; Fossa P; Cilia A; Prezzavento O; Ronsisvalle S; Aricò G; Parenti C; Brasili L
Eur J Med Chem; 2016 Apr; 112():1-19. PubMed ID: 26874044
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity.
Anzini M; Canullo L; Braile C; Cappelli A; Gallelli A; Vomero S; Menziani MC; De Benedetti PG; Rizzo M; Collina S; Azzolina O; Sbacchi M; Ghelardini C; Galeotti N
J Med Chem; 2003 Aug; 46(18):3853-64. PubMed ID: 12930147
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and Biological Evaluation of Novel σ1 Receptor Ligands for Treating Neuropathic Pain: 6-Hydroxypyridazinones.
Cao X; Chen Y; Zhang Y; Lan Y; Zhang J; Xu X; Qiu Y; Zhao S; Liu X; Liu BF; Zhang G
J Med Chem; 2016 Apr; 59(7):2942-61. PubMed ID: 27003636
[TBL] [Abstract][Full Text] [Related]
15. Medicinal Chemistry of σ
Weber F; Wünsch B
Handb Exp Pharmacol; 2017; 244():51-79. PubMed ID: 28620761
[TBL] [Abstract][Full Text] [Related]
16. Selective sigma-1 receptor antagonists for the treatment of pain.
Almansa C; Vela JM
Future Med Chem; 2014 Jun; 6(10):1179-99. PubMed ID: 25078137
[TBL] [Abstract][Full Text] [Related]
17. (+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties.
Ronsisvalle G; Marrazzo A; Prezzavento O; Pasquinucci L; Vittorio F; Pittalà V; Pappalardo MS; Cacciaguerra S; Spampinato S
J Med Chem; 1998 May; 41(10):1574-80. PubMed ID: 9572883
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands.
Romeo G; Prezzavento O; Intagliata S; Pittalà V; Modica MN; Marrazzo A; Turnaturi R; Parenti C; Chiechio S; Arena E; Campisi A; Sposito G; Salerno L
Eur J Med Chem; 2019 Jul; 174():226-235. PubMed ID: 31042618
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and receptor binding studies of some new arylcarboxamide derivatives as sigma-1 ligands.
Zampieri D; Laurini E; Vio L; Golob S; Fermeglia M; Pricl S; Mamolo MG
Bioorg Med Chem Lett; 2014 Feb; 24(4):1021-5. PubMed ID: 24486131
[TBL] [Abstract][Full Text] [Related]
20. 1,2,4-Triazolyl octahydropyrrolo[2,3-b]pyrroles: A new series of potent and selective dopamine D3 receptor antagonists.
Micheli F; Bernardelli A; Bianchi F; Braggio S; Castelletti L; Cavallini P; Cavanni P; Cremonesi S; Dal Cin M; Feriani A; Oliosi B; Semeraro T; Tarsi L; Tomelleri S; Wong A; Visentini F; Zonzini L; Heidbreder C
Bioorg Med Chem; 2016 Apr; 24(8):1619-36. PubMed ID: 26951894
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
