These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts. Lenos K; de Lange J; Teunisse AF; Lodder K; Verlaan-de Vries M; Wiercinska E; van der Burg MJ; Szuhai K; Jochemsen AG Mol Cancer; 2011 Sep; 10():111. PubMed ID: 21910853 [TBL] [Abstract][Full Text] [Related]
3. p53 regulation: teamwork between RING domains of Mdm2 and MdmX. Wang X Cell Cycle; 2011 Dec; 10(24):4225-9. PubMed ID: 22134240 [TBL] [Abstract][Full Text] [Related]
4. Mdm2 Splice isoforms regulate the p53/Mdm2/Mdm4 regulatory circuit via RING domain-mediated ubiquitination of p53 and Mdm4. Fan C; Wang X Cell Cycle; 2017 Apr; 16(7):660-664. PubMed ID: 28166445 [TBL] [Abstract][Full Text] [Related]
5. The human oncoprotein MDM2 uses distinct strategies to inhibit transcriptional activation mediated by the wild-type p53 and its tumor-derived mutants. Brown DR; Deb D; Frum R; Hickes L; Munoz R; Deb S; Deb SP Int J Oncol; 2001 Mar; 18(3):449-59. PubMed ID: 11179471 [TBL] [Abstract][Full Text] [Related]
6. A site-directed mutagenesis study of the MdmX RING domain. Egorova O; Mis M; Sheng Y Biochem Biophys Res Commun; 2014 May; 447(4):696-701. PubMed ID: 24755078 [TBL] [Abstract][Full Text] [Related]
7. Human MDM2 isoforms translated differentially on constitutive versus p53-regulated transcripts have distinct functions in the p53/MDM2 and TSG101/MDM2 feedback control loops. Cheng TH; Cohen SN Mol Cell Biol; 2007 Jan; 27(1):111-9. PubMed ID: 17060450 [TBL] [Abstract][Full Text] [Related]
8. MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts. Gentiletti F; Mancini F; D'Angelo M; Sacchi A; Pontecorvi A; Jochemsen AG; Moretti F Oncogene; 2002 Jan; 21(6):867-77. PubMed ID: 11840332 [TBL] [Abstract][Full Text] [Related]
10. Elevated MDM2 boosts the apoptotic activity of p53-MDM2 binding inhibitors by facilitating MDMX degradation. Xia M; Knezevic D; Tovar C; Huang B; Heimbrook DC; Vassilev LT Cell Cycle; 2008 Jun; 7(11):1604-12. PubMed ID: 18520179 [TBL] [Abstract][Full Text] [Related]
11. MDM2 interacts with MDMX through their RING finger domains. Tanimura S; Ohtsuka S; Mitsui K; Shirouzu K; Yoshimura A; Ohtsubo M FEBS Lett; 1999 Mar; 447(1):5-9. PubMed ID: 10218570 [TBL] [Abstract][Full Text] [Related]
12. p53 Stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products. Yin Y; Stephen CW; Luciani MG; Fåhraeus R Nat Cell Biol; 2002 Jun; 4(6):462-7. PubMed ID: 12032546 [TBL] [Abstract][Full Text] [Related]
13. Molecular basis for the inhibition of p53 by Mdmx. Popowicz GM; Czarna A; Rothweiler U; Szwagierczak A; Krajewski M; Weber L; Holak TA Cell Cycle; 2007 Oct; 6(19):2386-92. PubMed ID: 17938582 [TBL] [Abstract][Full Text] [Related]
14. A novel exon within the mdm2 gene modulates translation initiation in vitro and disrupts the p53-binding domain of mdm2 protein. Veldhoen N; Metcalfe S; Milner J Oncogene; 1999 Nov; 18(50):7026-33. PubMed ID: 10597303 [TBL] [Abstract][Full Text] [Related]
15. The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis. Brown DR; Thomas CA; Deb SP EMBO J; 1998 May; 17(9):2513-25. PubMed ID: 9564034 [TBL] [Abstract][Full Text] [Related]
16. DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation. Okamoto K; Kashima K; Pereg Y; Ishida M; Yamazaki S; Nota A; Teunisse A; Migliorini D; Kitabayashi I; Marine JC; Prives C; Shiloh Y; Jochemsen AG; Taya Y Mol Cell Biol; 2005 Nov; 25(21):9608-20. PubMed ID: 16227609 [TBL] [Abstract][Full Text] [Related]
17. Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase. Okamoto K; Taya Y; Nakagama H FEBS Lett; 2009 Sep; 583(17):2710-4. PubMed ID: 19619542 [TBL] [Abstract][Full Text] [Related]
18. Overexpression of Mdm2 and MdmX fusion proteins alters p53 mediated transactivation, ubiquitination, and degradation. Ghosh M; Huang K; Berberich SJ Biochemistry; 2003 Mar; 42(8):2291-9. PubMed ID: 12600196 [TBL] [Abstract][Full Text] [Related]
19. MdmX is a substrate for the deubiquitinating enzyme USP2a. Allende-Vega N; Sparks A; Lane DP; Saville MK Oncogene; 2010 Jan; 29(3):432-41. PubMed ID: 19838211 [TBL] [Abstract][Full Text] [Related]
20. MDMX: a novel p53-binding protein with some functional properties of MDM2. Shvarts A; Steegenga WT; Riteco N; van Laar T; Dekker P; Bazuine M; van Ham RC; van der Houven van Oordt W; Hateboer G; van der Eb AJ; Jochemsen AG EMBO J; 1996 Oct; 15(19):5349-57. PubMed ID: 8895579 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]