130 related articles for article (PubMed ID: 2565975)
1. Prodrugs of peptides. IV: Bioreversible derivatization of the pyroglutamyl group by N-acylation and N-aminomethylation to effect protection against pyroglutamyl aminopeptidase.
Bundgaard H; Møss J
J Pharm Sci; 1989 Feb; 78(2):122-6. PubMed ID: 2565975
[TBL] [Abstract][Full Text] [Related]
2. Prodrugs of peptides. 19. Protection of the pyroglutamyl residue against pyroglutamyl aminopeptidase by N-acyloxymethylation and other means.
Møss J; Bundgaard H
Acta Pharm Nord; 1992; 4(4):301-8. PubMed ID: 1363462
[TBL] [Abstract][Full Text] [Related]
3. Pyroglutamyl diazomethyl ketone: potent inhibitor of mammalian pyroglutamyl peptide hydrolase.
Wilk S; Friedman TC; Kline TB
Biochem Biophys Res Commun; 1985 Jul; 130(2):662-8. PubMed ID: 2862865
[TBL] [Abstract][Full Text] [Related]
4. Prodrugs of peptides. 6. Bioreversible derivatives of thyrotropin-releasing hormone (TRH) with increased lipophilicity and resistance to cleavage by the TRH-specific serum enzyme.
Bundgaard H; Møss J
Pharm Res; 1990 Sep; 7(9):885-92. PubMed ID: 2122435
[TBL] [Abstract][Full Text] [Related]
5. Activation and cytotoxicity of 2-alpha-aminoacyl prodrugs of methotrexate.
Smal MA; Dong Z; Cheung HT; Asano Y; Escoffier L; Costello M; Tattersall MH
Biochem Pharmacol; 1995 Feb; 49(4):567-74. PubMed ID: 7872963
[TBL] [Abstract][Full Text] [Related]
6. Inactivation of pyroglutamyl aminopeptidase by L-pyroglutamyl chloromethyl ketone.
Fujiwara K; Kitagawa T; Tsuru D
Biochim Biophys Acta; 1981 Mar; 658(1):10-6. PubMed ID: 6111350
[TBL] [Abstract][Full Text] [Related]
7. Prodrugs of peptides. 13. Stabilization of peptide amides against alpha-chymotrypsin by the prodrug approach.
Kahns AH; Bundgaard H
Pharm Res; 1991 Dec; 8(12):1533-8. PubMed ID: 1808620
[TBL] [Abstract][Full Text] [Related]
8. 5-Oxoprolinal: transition-state aldehyde inhibitor of pyroglutamyl-peptide hydrolase.
Friedman TC; Kline TB; Wilk S
Biochemistry; 1985 Jul; 24(15):3907-13. PubMed ID: 2864952
[TBL] [Abstract][Full Text] [Related]
9. N-alpha-carbobenzoxy pyroglutamyl diazomethyl ketone as active-site-directed inhibitor for pyroglutamyl peptidase.
Fujiwara K; Matsumoto E; Kitagawa T; Tsuru D
Biochim Biophys Acta; 1982 Apr; 702(2):149-54. PubMed ID: 6123347
[TBL] [Abstract][Full Text] [Related]
10. Inactivation of pyroglutamyl aminopeptidase by N alpha-carbobenzoxy-L-pyroglutamyl chloromethyl ketone.
Fujiwara K; Matsumoto E; Kitagawa T; Tsuru D
J Biochem; 1981 Aug; 90(2):433-7. PubMed ID: 6117551
[TBL] [Abstract][Full Text] [Related]
11. Specificity of a serum peptidase hydrolyzing thyroliberin at pyroglutamyl-histidine bone.
Bauer K; Nowak P; Kleinkauf H
Eur J Biochem; 1981 Aug; 118(1):173-6. PubMed ID: 6116600
[TBL] [Abstract][Full Text] [Related]
12. Aminopeptidases: aminopeptidase M (EC 3.4.11.2), pyroglutamate aminopeptidase (EC 3.4.19.3), and prolidase (EC 3.4.13.9).
Sweeney PJ; Walker JM
Methods Mol Biol; 1993; 16():319-29. PubMed ID: 19082982
[No Abstract] [Full Text] [Related]
13. The effect of inhibitors of prolyl endopeptidase and pyroglutamyl peptide hydrolase on TRH degradation in rat serum.
Friedman TC; Wilk S
Biochem Biophys Res Commun; 1985 Oct; 132(2):787-94. PubMed ID: 2865955
[TBL] [Abstract][Full Text] [Related]
14. Regulation of a thyrotropin-releasing hormone-degrading enzyme in GH3 cells: induction of pyroglutamyl peptidase I by 3,5,3'-triiodothyronine.
Suen CS; Wilk S
Endocrinology; 1987 Aug; 121(2):770-5. PubMed ID: 2885183
[TBL] [Abstract][Full Text] [Related]
15. Delineation of a particulate thyrotropin-releasing hormone-degrading enzyme in rat brain by the use of specific inhibitors of prolyl endopeptidase and pyroglutamyl peptide hydrolase.
Friedman TC; Wilk S
J Neurochem; 1986 Apr; 46(4):1231-9. PubMed ID: 2869108
[TBL] [Abstract][Full Text] [Related]
16. Hydrolysis of synthetic substrate, L-pyroglutamyl p-nitroanilide is catalyzed solely by pyroglutamyl aminopeptidase I in rat liver cytosol.
Abe K; Watanabe N; Kosaka T; Yamada M; Tokui T; Ikeda T
Biol Pharm Bull; 2003 Nov; 26(11):1528-33. PubMed ID: 14600395
[TBL] [Abstract][Full Text] [Related]
17. Facile analysis and purification of deblocked N-terminal pyroglutamyl peptides with a strong cation-exchange sulfoethyl aspartamide column.
Crimmins DL; McCourt DW; Schwartz BD
Biochem Biophys Res Commun; 1988 Oct; 156(2):910-6. PubMed ID: 2903737
[TBL] [Abstract][Full Text] [Related]
18. Prodrugs of peptides. 9. Bioreversible N-alpha-hydroxyalkylation of the peptide bond to effect protection against carboxypeptidase or other proteolytic enzymes.
Bundgaard H; Rasmussen GJ
Pharm Res; 1991 Mar; 8(3):313-22. PubMed ID: 2052517
[TBL] [Abstract][Full Text] [Related]
19. Purification and characterization of leucyl aminopeptidase and pyroglutamyl aminopeptidase from human skeletal muscle.
Mantle D; Lauffart B; Gibson A
Clin Chim Acta; 1991 Feb; 197(1):35-45. PubMed ID: 1675162
[TBL] [Abstract][Full Text] [Related]
20. An evaluation of the role of a pyroglutamyl peptidase, a post-proline cleaving enzyme and a post-proline dipeptidyl amino peptidase, each purified from the soluble fraction of guinea-pig brain, in the degradation of thyroliberin in vitro.
Browne P; O'Cuinn G
Eur J Biochem; 1983 Dec; 137(1-2):75-87. PubMed ID: 6140164
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
