BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 25667220)

  • 1. Pulmonary expression of CYP2A13 and ABCB1 is regulated by FOXA2, and their genetic interaction is associated with lung cancer.
    Xiang C; Wang J; Kou X; Chen X; Qin Z; Jiang Y; Sun C; Xu J; Tan W; Jin L; Lin D; He F; Wang H
    FASEB J; 2015 May; 29(5):1986-98. PubMed ID: 25667220
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK.
    Wang H; Tan W; Hao B; Miao X; Zhou G; He F; Lin D
    Cancer Res; 2003 Nov; 63(22):8057-61. PubMed ID: 14633739
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel mechanism of transcriptional repression of the human ATP binding cassette transporter A1 gene in hepatic cells by the winged helix/forkhead box transcription factor A2.
    Thymiakou E; Kardassis D
    Biochim Biophys Acta; 2014 Jun; 1839(6):526-36. PubMed ID: 24807696
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The missense genetic polymorphisms of human CYP2A13: functional significance in carcinogen activation and identification of a null allelic variant.
    Wang SL; He XY; Shen J; Wang JS; Hong JY
    Toxicol Sci; 2006 Nov; 94(1):38-45. PubMed ID: 16917071
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Su T; Bao Z; Zhang QY; Smith TJ; Hong JY; Ding X
    Cancer Res; 2000 Sep; 60(18):5074-9. PubMed ID: 11016631
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanisms of differential expression of the CYP2A13 7520C and 7520G alleles in human lung: allelic expression analysis for CYP2A13 heterogeneous nuclear RNA, and evidence for the involvement of multiple cis-regulatory single nucleotide polymorphisms.
    Wu H; Zhang X; Ling G; D'Agostino J; Ding X
    Pharmacogenet Genomics; 2009 Nov; 19(11):852-63. PubMed ID: 20431511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppression of pulmonary CYP2A13 expression by carcinogen-induced lung tumorigenesis in a CYP2A13-humanized mouse model.
    Liu Z; Megaraj V; Li L; Sell S; Hu J; Ding X
    Drug Metab Dispos; 2015 May; 43(5):698-702. PubMed ID: 25710941
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CYP2A13: variable expression and role in human lung microsomal metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Zhang X; D'Agostino J; Wu H; Zhang QY; von Weymarn L; Murphy SE; Ding X
    J Pharmacol Exp Ther; 2007 Nov; 323(2):570-8. PubMed ID: 17671098
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism-related enzymes gene polymorphisms, NNK metabolites levels and urothelial carcinoma.
    Chung CJ; Pu YS; Shiue HS; Lee HL; Lin P; Yang HY; Su CT; Hsueh YM
    Toxicol Lett; 2013 Jan; 216(1):16-22. PubMed ID: 23142425
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic susceptibility of lung cancer associated with common variants in the 3' untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1) and ABCC1 candidate transporter genes for carcinogen export.
    Wang H; Jin G; Wang H; Liu G; Qian J; Jin L; Wei Q; Shen H; Huang W; Lu D
    Cancer; 2009 Feb; 115(3):595-607. PubMed ID: 19107762
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of CYP2A13*2, a variant cytochrome P450 allele previously found to be associated with decreased incidences of lung adenocarcinoma in smokers.
    D'Agostino J; Zhang X; Wu H; Ling G; Wang S; Zhang QY; Liu F; Ding X
    Drug Metab Dispos; 2008 Nov; 36(11):2316-23. PubMed ID: 18669584
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide.
    Hu DG; Gardner-Stephen D; Severi G; Gregory PA; Treloar J; Giles GG; English DR; Hopper JL; Tilley WD; Mackenzie PI
    Mol Pharmacol; 2010 Oct; 78(4):714-22. PubMed ID: 20628005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcriptional regulation of human CYP2A13 expression in the respiratory tract by CCAAT/enhancer binding protein and epigenetic modulation.
    Ling G; Wei Y; Ding X
    Mol Pharmacol; 2007 Mar; 71(3):807-16. PubMed ID: 17148654
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic and Enzymatic Characteristics of CYP2A13 in Relation to Lung Damage.
    Vrzal R
    Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830188
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis of CYP2A contributions to metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human peripheral lung microsomes.
    Brown PJ; Bedard LL; Reid KR; Petsikas D; Massey TE
    Drug Metab Dispos; 2007 Nov; 35(11):2086-94. PubMed ID: 17717079
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of a real-time polymerase chain reaction-based method for the measurement of relative allelic expression and identification of CYP2A13 alleles with decreased expression in human lung.
    Zhang X; Caggana M; Cutler TL; Ding X
    J Pharmacol Exp Ther; 2004 Oct; 311(1):373-81. PubMed ID: 15175424
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transcriptional suppression of CYP2A13 expression by lipopolysaccharide in cultured human lung cells and the lungs of a CYP2A13-humanized mouse model.
    Wu H; Liu Z; Ling G; Lawrence D; Ding X
    Toxicol Sci; 2013 Oct; 135(2):476-85. PubMed ID: 23884085
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transcriptional networks in the liver: hepatocyte nuclear factor 6 function is largely independent of Foxa2.
    Rubins NE; Friedman JR; Le PP; Zhang L; Brestelli J; Kaestner KH
    Mol Cell Biol; 2005 Aug; 25(16):7069-77. PubMed ID: 16055718
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FOXA2 regulates a network of genes involved in critical functions of human intestinal epithelial cells.
    Gosalia N; Yang R; Kerschner JL; Harris A
    Physiol Genomics; 2015 Jul; 47(7):290-7. PubMed ID: 25921584
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody.
    Zhu LR; Thomas PE; Lu G; Reuhl KR; Yang GY; Wang LD; Wang SL; Yang CS; He XY; Hong JY
    Drug Metab Dispos; 2006 Oct; 34(10):1672-6. PubMed ID: 16815959
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.