These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

323 related articles for article (PubMed ID: 25670500)

  • 61. Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
    Liang WC; Xi H; Sun D; D'Ascenzo L; Zarzar J; Stephens N; Cook R; Li Y; Ye Z; Matsumoto M; Payandeh J; Masureel M; Wu Y
    MAbs; 2024; 16(1):2309685. PubMed ID: 38356181
    [TBL] [Abstract][Full Text] [Related]  

  • 62. A large human domain antibody library combining heavy and light chain CDR3 diversity.
    Chen W; Zhu Z; Feng Y; Dimitrov DS
    Mol Immunol; 2010 Jan; 47(4):912-21. PubMed ID: 19883941
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Germline-Dependent Antibody Paratope States and Pairing Specific V
    Fernández-Quintero ML; Kroell KB; Bacher LM; Loeffler JR; Quoika PK; Georges G; Bujotzek A; Kettenberger H; Liedl KR
    Front Immunol; 2021; 12():675655. PubMed ID: 34447370
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex.
    Tulip WR; Varghese JN; Laver WG; Webster RG; Colman PM
    J Mol Biol; 1992 Sep; 227(1):122-48. PubMed ID: 1381757
    [TBL] [Abstract][Full Text] [Related]  

  • 65. The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies.
    Rothe C; Urlinger S; Löhning C; Prassler J; Stark Y; Jäger U; Hubner B; Bardroff M; Pradel I; Boss M; Bittlingmaier R; Bataa T; Frisch C; Brocks B; Honegger A; Urban M
    J Mol Biol; 2008 Feb; 376(4):1182-200. PubMed ID: 18191144
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Redesigning an antibody H3 loop by virtual screening of a small library of human germline-derived sequences.
    Corbeil CR; Manenda MS; Sulea T; Baardsnes J; Picard MÈ; Hogues H; Gaudreault F; Deprez C; Shi R; Purisima EO
    Sci Rep; 2021 Nov; 11(1):21362. PubMed ID: 34725391
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Systematic classification of CDR-L3 in antibodies: implications of the light chain subtypes and the VL-VH interface.
    Kuroda D; Shirai H; Kobori M; Nakamura H
    Proteins; 2009 Apr; 75(1):139-46. PubMed ID: 18798566
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Drug-like antibodies with high affinity, diversity and developability directly from next-generation antibody libraries.
    Azevedo Reis Teixeira A; Erasmus MF; D'Angelo S; Naranjo L; Ferrara F; Leal-Lopes C; Durrant O; Galmiche C; Morelli A; Scott-Tucker A; Bradbury ARM
    MAbs; 2021; 13(1):1980942. PubMed ID: 34850665
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Novel, provable algorithms for efficient ensemble-based computational protein design and their application to the redesign of the c-Raf-RBD:KRas protein-protein interface.
    Lowegard AU; Frenkel MS; Holt GT; Jou JD; Ojewole AA; Donald BR
    PLoS Comput Biol; 2020 Jun; 16(6):e1007447. PubMed ID: 32511232
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Coupling Protein Side-Chain and Backbone Flexibility Improves the Re-design of Protein-Ligand Specificity.
    Ollikainen N; de Jong RM; Kortemme T
    PLoS Comput Biol; 2015; 11(9):e1004335. PubMed ID: 26397464
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Improving the accuracy of the structure prediction of the third hypervariable loop of the heavy chains of antibodies.
    Messih MA; Lepore R; Marcatili P; Tramontano A
    Bioinformatics; 2014 Oct; 30(19):2733-40. PubMed ID: 24930144
    [TBL] [Abstract][Full Text] [Related]  

  • 72. A critical analysis of computational protein design with sparse residue interaction graphs.
    Jain S; Jou JD; Georgiev IS; Donald BR
    PLoS Comput Biol; 2017 Mar; 13(3):e1005346. PubMed ID: 28358804
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration.
    Koenig P; Lee CV; Sanowar S; Wu P; Stinson J; Harris SF; Fuh G
    J Biol Chem; 2015 Sep; 290(36):21773-86. PubMed ID: 26088137
    [TBL] [Abstract][Full Text] [Related]  

  • 74. A novel heavy domain antibody library with functionally optimized complementarity determining regions.
    Mandrup OA; Friis NA; Lykkemark S; Just J; Kristensen P
    PLoS One; 2013; 8(10):e76834. PubMed ID: 24116173
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences.
    Sevy AM; Jacobs TM; Crowe JE; Meiler J
    PLoS Comput Biol; 2015 Jul; 11(7):e1004300. PubMed ID: 26147100
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Rosetta:MSF: a modular framework for multi-state computational protein design.
    Löffler P; Schmitz S; Hupfeld E; Sterner R; Merkl R
    PLoS Comput Biol; 2017 Jun; 13(6):e1005600. PubMed ID: 28604768
    [TBL] [Abstract][Full Text] [Related]  

  • 77. [Molecular modeling of immunological proteins by bioinformatics].
    Nakamura H
    Nihon Rinsho; 1998 Mar; 56(3):795-802. PubMed ID: 9549375
    [TBL] [Abstract][Full Text] [Related]  

  • 78. SDR grafting--a new approach to antibody humanization.
    Kashmiri SV; De Pascalis R; Gonzales NR; Schlom J
    Methods; 2005 May; 36(1):25-34. PubMed ID: 15848072
    [TBL] [Abstract][Full Text] [Related]  

  • 79. A general computational approach for repeat protein design.
    Parmeggiani F; Huang PS; Vorobiev S; Xiao R; Park K; Caprari S; Su M; Seetharaman J; Mao L; Janjua H; Montelione GT; Hunt J; Baker D
    J Mol Biol; 2015 Jan; 427(2):563-75. PubMed ID: 25451037
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Incorporating an allosteric regulatory site in an antibody through backbone design.
    Khersonsky O; Fleishman SJ
    Protein Sci; 2017 Apr; 26(4):807-813. PubMed ID: 28142198
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.