These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1171 related articles for article (PubMed ID: 25670854)

  • 21. CDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion.
    Jin X; Yang C; Fan P; Xiao J; Zhang W; Zhan S; Liu T; Wang D; Wu H
    J Biol Chem; 2017 Apr; 292(15):6269-6280. PubMed ID: 28242758
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis.
    Huang HL; Weng HY; Wang LQ; Yu CH; Huang QJ; Zhao PP; Wen JZ; Zhou H; Qu LH
    Mol Cancer Ther; 2012 May; 11(5):1155-65. PubMed ID: 22389469
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase.
    Koepp DM; Schaefer LK; Ye X; Keyomarsi K; Chu C; Harper JW; Elledge SJ
    Science; 2001 Oct; 294(5540):173-7. PubMed ID: 11533444
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12.
    Khan OM; Almagro J; Nelson JK; Horswell S; Encheva V; Keyan KS; Clurman BE; Snijders AP; Behrens A
    Nat Commun; 2021 Apr; 12(1):2043. PubMed ID: 33824312
    [TBL] [Abstract][Full Text] [Related]  

  • 25. F-box and WD repeat domain-containing-7 (Fbxw7) protein targets endoplasmic reticulum-anchored osteogenic and chondrogenic transcriptional factors for degradation.
    Yumimoto K; Matsumoto M; Onoyama I; Imaizumi K; Nakayama KI
    J Biol Chem; 2013 Oct; 288(40):28488-502. PubMed ID: 23955342
    [TBL] [Abstract][Full Text] [Related]  

  • 26. ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
    Ji S; Qin Y; Shi S; Liu X; Hu H; Zhou H; Gao J; Zhang B; Xu W; Liu J; Liang D; Liu L; Liu C; Long J; Zhou H; Chiao PJ; Xu J; Ni Q; Gao D; Yu X
    Cell Res; 2015 May; 25(5):561-73. PubMed ID: 25753158
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7.
    Thompson BJ; Jankovic V; Gao J; Buonamici S; Vest A; Lee JM; Zavadil J; Nimer SD; Aifantis I
    J Exp Med; 2008 Jun; 205(6):1395-408. PubMed ID: 18474632
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A phosphorylation cascade controls the degradation of active SREBP1.
    Bengoechea-Alonso MT; Ericsson J
    J Biol Chem; 2009 Feb; 284(9):5885-95. PubMed ID: 19126544
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The stomatin-like protein SLP-1 and Cdk2 interact with the F-Box protein Fbw7-γ.
    Zhang W; MacDonald EM; Koepp DM
    PLoS One; 2012; 7(10):e47736. PubMed ID: 23082202
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Glycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1.
    Biswas M; Kwong EK; Park E; Nagra P; Chan JY
    Exp Cell Res; 2013 Aug; 319(13):1922-1931. PubMed ID: 23623971
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
    Hao B; Oehlmann S; Sowa ME; Harper JW; Pavletich NP
    Mol Cell; 2007 Apr; 26(1):131-43. PubMed ID: 17434132
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development.
    Kitagawa K; Shibata K; Matsumoto A; Matsumoto M; Ohhata T; Nakayama KI; Niida H; Kitagawa M
    Mol Cell Biol; 2014 Jul; 34(14):2732-44. PubMed ID: 24820417
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Ubiquitin ligase Fbw7 restricts the replication of hepatitis C virus by targeting NS5B for ubiquitination and degradation.
    Chen J; Wu X; Chen S; Chen S; Xiang N; Chen Y; Guo D
    Biochem Biophys Res Commun; 2016 Feb; 470(3):697-703. PubMed ID: 26774344
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.
    Tron AE; Arai T; Duda DM; Kuwabara H; Olszewski JL; Fujiwara Y; Bahamon BN; Signoretti S; Schulman BA; DeCaprio JA
    Mol Cell; 2012 Apr; 46(1):67-78. PubMed ID: 22405651
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.
    Min SH; Lau AW; Lee TH; Inuzuka H; Wei S; Huang P; Shaik S; Lee DY; Finn G; Balastik M; Chen CH; Luo M; Tron AE; Decaprio JA; Zhou XZ; Wei W; Lu KP
    Mol Cell; 2012 Jun; 46(6):771-83. PubMed ID: 22608923
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Multisite phosphorylation of the Saccharomyces cerevisiae filamentous growth regulator Tec1 is required for its recognition by the E3 ubiquitin ligase adaptor Cdc4 and its subsequent destruction in vivo.
    Bao MZ; Shock TR; Madhani HD
    Eukaryot Cell; 2010 Jan; 9(1):31-6. PubMed ID: 19897738
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Ras activity regulates cyclin E degradation by the Fbw7 pathway.
    Minella AC; Welcker M; Clurman BE
    Proc Natl Acad Sci U S A; 2005 Jul; 102(27):9649-54. PubMed ID: 15980150
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
    Yada M; Hatakeyama S; Kamura T; Nishiyama M; Tsunematsu R; Imaki H; Ishida N; Okumura F; Nakayama K; Nakayama KI
    EMBO J; 2004 May; 23(10):2116-25. PubMed ID: 15103331
    [TBL] [Abstract][Full Text] [Related]  

  • 39. FBW7 targets KLF10 for ubiquitin-dependent degradation.
    Yu S; Wang F; Tan X; Gao GL; Pan WJ; Luan Y; Ge X
    Biochem Biophys Res Commun; 2018 Jan; 495(2):2092-2097. PubMed ID: 29198712
    [TBL] [Abstract][Full Text] [Related]  

  • 40. MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression.
    Lerner M; Lundgren J; Akhoondi S; Jahn A; Ng HF; Akbari Moqadam F; Oude Vrielink JA; Agami R; Den Boer ML; Grandér D; Sangfelt O
    Cell Cycle; 2011 Jul; 10(13):2172-83. PubMed ID: 21597324
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 59.