BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 25671308)

  • 1. A fatal combination: a thymidylate synthase inhibitor with DNA damaging activity.
    Ligasová A; Strunin D; Friedecký D; Adam T; Koberna K
    PLoS One; 2015; 10(2):e0117459. PubMed ID: 25671308
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 5-Nitro-2'-deoxyuridine and 5-nitro-2'-deoxyuridine 5'-monophosphate: antiviral activity and inhibition of thymidylate synthetase in vivo.
    De Clercq E; Descamps J; Huang GF; Torrence PF
    Mol Pharmacol; 1978 May; 14(3):422-30. PubMed ID: 661811
    [No Abstract]   [Full Text] [Related]  

  • 3. Dissociation of thymidylate biosynthesis from DNA biosynthesis by 5-fluoro-2'-deoxyuridine and 5,8-dideazaisofolic acid.
    Fernandes DJ; Cranford SK
    Cancer Res; 1986 Apr; 46(4 Pt 1):1741-7. PubMed ID: 2936450
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 5-Ethynyl-2'-deoxycytidine as a new agent for DNA labeling: detection of proliferating cells.
    Qu D; Wang G; Wang Z; Zhou L; Chi W; Cong S; Ren X; Liang P; Zhang B
    Anal Biochem; 2011 Oct; 417(1):112-21. PubMed ID: 21683679
    [TBL] [Abstract][Full Text] [Related]  

  • 5. EdU induces DNA damage response and cell death in mESC in culture.
    Kohlmeier F; Maya-Mendoza A; Jackson DA
    Chromosome Res; 2013 Mar; 21(1):87-100. PubMed ID: 23463495
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.
    Yin MB; Guo B; Panadero A; Frank C; Wrzosek C; Slocum HK; Rustum YM
    Exp Cell Res; 1999 Feb; 247(1):189-99. PubMed ID: 10047461
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of thymidylate synthase by hydroxyurea in rapidly proliferating P815 mastocytoma cells.
    Boehm TL; Kreis W; Drahovsky D
    Biochim Biophys Acta; 1982 Jan; 696(1):52-6. PubMed ID: 6805512
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thymidylate synthase inhibition in cells with arrested DNA synthesis is not due to an allosteric interaction in the replitase complex.
    Rode W; Jastreboff MM; Bertino JR
    Biochem Biophys Res Commun; 1985 Apr; 128(1):345-51. PubMed ID: 3921023
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Different rates of DNA replication at early versus late S-phase sections: multiscale modeling of stochastic events related to DNA content/EdU (5-ethynyl-2'deoxyuridine) incorporation distributions.
    Li B; Zhao H; Rybak P; Dobrucki JW; Darzynkiewicz Z; Kimmel M
    Cytometry A; 2014 Sep; 85(9):785-97. PubMed ID: 24894899
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells.
    Matsui SI; Arredondo MA; Wrzosek C; Rustum YM
    Cancer Res; 1996 Oct; 56(20):4715-23. PubMed ID: 8840989
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism of cell death following thymidylate synthase inhibition: 2'-deoxyuridine-5'-triphosphate accumulation, DNA damage, and growth inhibition following exposure to CB3717 and dipyridamole.
    Curtin NJ; Harris AL; Aherne GW
    Cancer Res; 1991 May; 51(9):2346-52. PubMed ID: 2015598
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell-cycle analyses using thymidine analogues in fission yeast.
    Anda S; Boye E; Grallert B
    PLoS One; 2014; 9(2):e88629. PubMed ID: 24551125
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhancement of 5-fluoro-2'-deoxyuridine antineoplastic activity by 5-benzyloxybenzyloxybenzylacyclouridine in a human colon carcinoma cell line.
    Chu E; Chu MY; Darnowski JW; Chen ZH; Pan BC; Chu SH
    Cancer Res; 1992 Apr; 52(7):1729-36. PubMed ID: 1532344
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cell type specific applicability of 5-ethynyl-2'-deoxyuridine (EdU) for dynamic proliferation assessment in flow cytometry.
    Diermeier-Daucher S; Clarke ST; Hill D; Vollmann-Zwerenz A; Bradford JA; Brockhoff G
    Cytometry A; 2009 Jun; 75(6):535-46. PubMed ID: 19235202
    [TBL] [Abstract][Full Text] [Related]  

  • 15. P21Cip1 is a critical mediator of the cytotoxic action of thymidylate synthase inhibitors in colorectal carcinoma cells.
    Geller JI; Szekely-Szucs K; Petak I; Doyle B; Houghton JA
    Cancer Res; 2004 Sep; 64(17):6296-303. PubMed ID: 15342418
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessment of growth-limiting events caused by 5-fluorouracil in mouse cells and in human cells.
    Evans RM; Laskin JD; Hakala MT
    Cancer Res; 1980 Nov; 40(11):4113-22. PubMed ID: 6162543
    [No Abstract]   [Full Text] [Related]  

  • 17. Thymidylate synthase is the principal target enzyme for the cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine against murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 or type 2 thymidine kinase gene.
    Balzarini J; De Clercq E; Verbruggen A; Ayusawa D; Shimizu K; Seno T
    Mol Pharmacol; 1987 Sep; 32(3):410-6. PubMed ID: 2823092
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of ethynyl-2'-deoxyuridine chemical probes for cell proliferation.
    Lovitt CJ; Hilko DH; Avery VM; Poulsen SA
    Bioorg Med Chem; 2016 Sep; 24(18):4272-4280. PubMed ID: 27460697
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of thymidylate synthase activity by antisense oligodeoxynucleotide and possible role in thymineless treatment.
    Lin SB; Ts'o PO; Sun SK; Choo KB; Yang FY; Lim YP; Tsai HL; Au LC
    Mol Pharmacol; 2001 Sep; 60(3):474-9. PubMed ID: 11502877
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thymidylate synthase inhibition induces S-phase arrest, biphasic mitochondrial alterations and caspase-dependent apoptosis in leukaemia cells.
    Sakoff JA; Ackland SP
    Cancer Chemother Pharmacol; 2000; 46(6):477-87. PubMed ID: 11138461
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.