These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 25676864)

  • 1. Vitamin D3 analogues that contain modified A- and seco-B-rings as hedgehog pathway inhibitors.
    DeBerardinis AM; Raccuia DS; Thompson EN; Maschinot CA; Kyle Hadden M
    Eur J Med Chem; 2015 Mar; 93():156-71. PubMed ID: 25676864
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and evaluation of hybrid vitamin D3 side chain analogues as hedgehog pathway inhibitors.
    Banerjee U; DeBerardinis AM; Hadden MK
    Bioorg Med Chem; 2015 Feb; 23(3):548-55. PubMed ID: 25549899
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of third generation vitamin D3 analogues as inhibitors of Hedgehog signaling.
    Maschinot CA; Chau LQ; Wechsler-Reya RJ; Hadden MK
    Eur J Med Chem; 2019 Jan; 162():495-506. PubMed ID: 30471551
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships for vitamin D3-based aromatic a-ring analogues as hedgehog pathway inhibitors.
    Deberardinis AM; Madden DJ; Banerjee U; Sail V; Raccuia DS; De Carlo D; Lemieux SM; Meares A; Hadden MK
    J Med Chem; 2014 May; 57(9):3724-36. PubMed ID: 24730984
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of vitamin D3 A-ring analogues as Hedgehog pathway inhibitors.
    Banerjee U; Ghosh M; Kyle Hadden M
    Bioorg Med Chem Lett; 2012 Feb; 22(3):1330-4. PubMed ID: 22226657
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of vitamin D3 analogues with C-11 modifications as inhibitors of Hedgehog signaling.
    Maschinot CA; Hadden MK
    Bioorg Med Chem Lett; 2017 Sep; 27(17):4011-4014. PubMed ID: 28780161
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Affinity-based protein profiling identifies vitamin D3 as a heat shock protein 70 antagonist that regulates hedgehog transduction in murine basal cell carcinoma.
    Wen J; Hadden MK
    Eur J Med Chem; 2022 Jan; 228():114005. PubMed ID: 34844141
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-Activity Relationship Studies of Vitamin D3 Analogues Containing an Ether or Thioether Linker as Hedgehog Pathway Inhibitors.
    Wen J; Hadden MK
    ChemMedChem; 2018 Apr; 13(7):748-753. PubMed ID: 29409113
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and biological evaluation of optimized phthalazine derivatives as hedgehog signaling pathway inhibitors.
    Lu X; Peng Y; Wang C; Yang J; Bao X; Dong Q; Zhao W; Tan W; Dong X
    Eur J Med Chem; 2017 Sep; 138():384-395. PubMed ID: 28688278
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 20-Cyclopropyl-cholecalciferol vitamin D3 analogs: a unique class of potent inhibitors of proliferation of human prostate, breast and myeloid leukemia cell lines.
    Koike M; Koshizuka K; Kawabata H; Yang R; Taub HE; Said J; Uskokovic M; Tsuruoka N; Koeffler HP
    Anticancer Res; 1999; 19(3A):1689-97. PubMed ID: 10470102
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of vitamin d3-based hedgehog pathway inhibitors that incorporate an aromatic a-ring isostere.
    DeBerardinis AM; Banerjee U; Hadden MK
    ACS Med Chem Lett; 2013 Jul; 4(7):590-5. PubMed ID: 24900716
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Probing the structural requirements for vitamin D3 inhibition of the hedgehog signaling pathway.
    DeBerardinis AM; Banerjee U; Miller M; Lemieux S; Hadden MK
    Bioorg Med Chem Lett; 2012 Jul; 22(14):4859-63. PubMed ID: 22687748
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Probing seco-steroid inhibition of the hedgehog signaling pathway.
    Thompson EN; Sail V; Raccuia DS; Hadden MK
    Mol Cell Biochem; 2019 Jan; 450(1-2):75-85. PubMed ID: 29876765
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and evaluation of novel dimethylpyridazine derivatives as hedgehog signaling pathway inhibitors.
    Wang C; Zhu M; Lu X; Wang H; Zhao W; Zhang X; Dong X
    Bioorg Med Chem; 2018 Jul; 26(12):3308-3320. PubMed ID: 29739714
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recent advances in the design of Hedgehog pathway inhibitors for the treatment of malignancies.
    Banerjee U; Hadden MK
    Expert Opin Drug Discov; 2014 Jul; 9(7):751-71. PubMed ID: 24850423
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, conformational analysis, and biological evaluation of 19-nor-vitamin D3 analogues with A-ring modifications.
    Sánchez-Abella L; Fernández S; Verstuyf A; Verlinden L; Gotor V; Ferrero M
    J Med Chem; 2009 Oct; 52(19):6158-62. PubMed ID: 19739672
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel Gemini-vitamin D3 analog inhibits tumor cell growth and modulates the Akt/mTOR signaling pathway.
    O'Kelly J; Uskokovic M; Lemp N; Vadgama J; Koeffler HP
    J Steroid Biochem Mol Biol; 2006 Aug; 100(4-5):107-16. PubMed ID: 16777406
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors.
    Bhattarai D; Jung JH; Han S; Lee H; Oh SJ; Ko HW; Lee K
    Eur J Med Chem; 2017 Jan; 125():1036-1050. PubMed ID: 27810591
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of novel vitamin D3 analog with an additional ring annulated to A and seco-B rings.
    Sokolowska K; Sicinski RR
    Steroids; 2014 Sep; 87():67-75. PubMed ID: 24928728
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of 1α,25-dihydroxyvitamin D(3) analogues hydroxymethylated at C-26.
    Regueira MA; Samanta S; Malloy PJ; Ordonez-Moran P; Resende D; Sussman F; Munoz A; Mourino A; Feldman D; Torneiro M
    J Med Chem; 2011 Jun; 54(11):3950-62. PubMed ID: 21524075
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.