Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1719 related articles for article (PubMed ID: 25683911)

  • 1. Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells.
    Vera J; Raatz Y; Wolkenhauer O; Kottek T; Bhattacharya A; Simon JC; Kunz M
    Cell Signal; 2015 May; 27(5):951-60. PubMed ID: 25683911
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
    Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1.
    Tse AN; Sheikh TN; Alan H; Chou TC; Schwartz GK
    Mol Pharmacol; 2009 Jan; 75(1):124-33. PubMed ID: 18820127
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Osteoblasts survive the arsenic trioxide treatment by activation of ATM-mediated pathway.
    Hu YC; Hsieh BS; Cheng HL; Huang LW; Huang TC; Huang IY; Chang KL
    Biochem Pharmacol; 2013 Apr; 85(7):1018-26. PubMed ID: 23337567
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chk1, but not Chk2, is responsible for G2/M phase arrest induced by diallyl disulfide in human gastric cancer BGC823 cells.
    Bo S; Hui H; Li W; Hui L; Hong X; Lin D; Dai WX; Wu YH; Ai XH; Hao J; Qi S
    Food Chem Toxicol; 2014 Jun; 68():61-70. PubMed ID: 24650757
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATM-Chk2-Cdc25A and ATM-p53-p21-pathways.
    Gaul L; Mandl-Weber S; Baumann P; Emmerich B; Schmidmaier R
    J Cancer Res Clin Oncol; 2008 Feb; 134(2):245-53. PubMed ID: 17653574
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hsp90-inhibitor geldanamycin abrogates G2 arrest in p53-negative leukemia cell lines through the depletion of Chk1.
    Sugimoto K; Sasaki M; Isobe Y; Tsutsui M; Suto H; Ando J; Tamayose K; Ando M; Oshimi K
    Oncogene; 2008 May; 27(22):3091-101. PubMed ID: 18071310
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways.
    Ouyang G; Yao L; Ruan K; Song G; Mao Y; Bao S
    Cell Biol Int; 2009 Dec; 33(12):1237-44. PubMed ID: 19732843
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sterigmatocystin induces G1 arrest in primary human esophageal epithelial cells but induces G2 arrest in immortalized cells: key mechanistic differences in these two models.
    Wang J; Huang S; Xing L; Cui J; Tian Z; Shen H; Jiang X; Yan X; Wang J; Zhang X
    Arch Toxicol; 2015 Nov; 89(11):2015-25. PubMed ID: 25294323
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells.
    Wang Y; Liu Q; Liu Z; Li B; Sun Z; Zhou H; Zhang X; Gong Y; Shao C
    Mutat Res; 2012 Jun; 734(1-2):20-9. PubMed ID: 22561209
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways.
    Tian H; Faje AT; Lee SL; Jorgensen TJ
    Neoplasia; 2002; 4(2):171-80. PubMed ID: 11896572
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.
    Shin DY; Sung Kang H; Kim GY; Kim WJ; Yoo YH; Choi YH
    Biomed Pharmacother; 2013 May; 67(4):305-11. PubMed ID: 23582784
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bortezomib induces G2-M arrest in human colon cancer cells through ROS-inducible phosphorylation of ATM-CHK1.
    Hong YS; Hong SW; Kim SM; Jin DH; Shin JS; Yoon DH; Kim KP; Lee JL; Heo DS; Lee JS; Kim TW
    Int J Oncol; 2012 Jul; 41(1):76-82. PubMed ID: 22552540
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation.
    Yan Y; Spieker RS; Kim M; Stoeger SM; Cowan KH
    Oncogene; 2005 May; 24(20):3285-96. PubMed ID: 15735702
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of the G2/M transition by p53.
    Taylor WR; Stark GR
    Oncogene; 2001 Apr; 20(15):1803-15. PubMed ID: 11313928
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mangiferin induces cell cycle arrest at G2/M phase through ATR-Chk1 pathway in HL-60 leukemia cells.
    Peng ZG; Yao YB; Yang J; Tang YL; Huang X
    Genet Mol Res; 2015 May; 14(2):4989-5002. PubMed ID: 25966274
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Irradiation-induced G2/M checkpoint response requires ERK1/2 activation.
    Yan Y; Black CP; Cowan KH
    Oncogene; 2007 Jul; 26(32):4689-98. PubMed ID: 17297454
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway.
    Chaudhary P; Sharma R; Sahu M; Vishwanatha JK; Awasthi S; Awasthi YC
    J Biol Chem; 2013 Jul; 288(28):20532-46. PubMed ID: 23733185
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of cell cycle checkpoint kinase WEE1 by miR-195 in malignant melanoma.
    Bhattacharya A; Schmitz U; Wolkenhauer O; Schönherr M; Raatz Y; Kunz M
    Oncogene; 2013 Jun; 32(26):3175-83. PubMed ID: 22847610
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis.
    Pan Y; Ren KH; He HW; Shao RG
    Cancer Biol Ther; 2009 Aug; 8(16):1559-66. PubMed ID: 19502782
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 86.