BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1717 related articles for article (PubMed ID: 25683911)

  • 21. Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway.
    Rong JJ; Hu R; Song XM; Ha J; Lu N; Qi Q; Tao L; You QD; Guo QL
    Cancer Lett; 2010 Oct; 296(1):55-64. PubMed ID: 20413215
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
    Castedo M; Perfettini JL; Roumier T; Yakushijin K; Horne D; Medema R; Kroemer G
    Oncogene; 2004 May; 23(25):4353-61. PubMed ID: 15048074
    [TBL] [Abstract][Full Text] [Related]  

  • 23. DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.
    Caporali S; Falcinelli S; Starace G; Russo MT; Bonmassar E; Jiricny J; D'Atri S
    Mol Pharmacol; 2004 Sep; 66(3):478-91. PubMed ID: 15322239
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.
    Baranski Z; Booij TH; Cleton-Jansen AM; Price LS; van de Water B; Bovée JV; Hogendoorn PC; Danen EH
    J Pathol; 2015 Jul; 236(3):348-59. PubMed ID: 25757065
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Diallyl disulfide selectively causes checkpoint kinase-1 mediated G2/M arrest in human MGC803 gastric cancer cell line.
    Ling H; Lu LF; He J; Xiao GH; Jiang H; Su Q
    Oncol Rep; 2014 Nov; 32(5):2274-82. PubMed ID: 25176258
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin.
    Zimmermann M; Arachchige-Don AS; Donaldson MS; Dallapiazza RF; Cowan CE; Horne MC
    J Biol Chem; 2012 Jun; 287(27):22838-53. PubMed ID: 22589537
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Induction of G2/M arrest by pseudolaric acid B is mediated by activation of the ATM signaling pathway.
    Meng AG; Jiang LL
    Acta Pharmacol Sin; 2009 Apr; 30(4):442-50. PubMed ID: 19305423
    [TBL] [Abstract][Full Text] [Related]  

  • 28. miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress.
    Lezina L; Purmessur N; Antonov AV; Ivanova T; Karpova E; Krishan K; Ivan M; Aksenova V; Tentler D; Garabadgiu AV; Melino G; Barlev NA
    Cell Death Dis; 2013 Dec; 4(12):e953. PubMed ID: 24336073
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma.
    Chilà R; Basana A; Lupi M; Guffanti F; Gaudio E; Rinaldi A; Cascione L; Restelli V; Tarantelli C; Bertoni F; Damia G; Carrassa L
    Oncotarget; 2015 Feb; 6(5):3394-408. PubMed ID: 25428911
    [TBL] [Abstract][Full Text] [Related]  

  • 30. E2F1-dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells.
    Li Y; Shao J; Shen K; Xu Y; Liu J; Qian X
    J Cell Biochem; 2012 Oct; 113(10):3165-77. PubMed ID: 22593008
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
    Hirose Y; Berger MS; Pieper RO
    Cancer Res; 2001 Aug; 61(15):5843-9. PubMed ID: 11479224
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cadmium-induced DNA damage triggers G(2)/M arrest via chk1/2 and cdc2 in p53-deficient kidney proximal tubule cells.
    Bork U; Lee WK; Kuchler A; Dittmar T; Thévenod F
    Am J Physiol Renal Physiol; 2010 Feb; 298(2):F255-65. PubMed ID: 19923412
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces G₂/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells.
    Kim JY; Choi HE; Lee HH; Shin JS; Shin DH; Choi JH; Lee YS; Lee KT
    Oncol Rep; 2015 May; 33(5):2639-47. PubMed ID: 25812484
    [TBL] [Abstract][Full Text] [Related]  

  • 34. A regimen combining the Wee1 inhibitor AZD1775 with HDAC inhibitors targets human acute myeloid leukemia cells harboring various genetic mutations.
    Zhou L; Zhang Y; Chen S; Kmieciak M; Leng Y; Lin H; Rizzo KA; Dumur CI; Ferreira-Gonzalez A; Dai Y; Grant S
    Leukemia; 2015 Apr; 29(4):807-18. PubMed ID: 25283841
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
    Huang SH; Wu LW; Huang AC; Yu CC; Lien JC; Huang YP; Yang JS; Yang JH; Hsiao YP; Wood WG; Yu CS; Chung JG
    J Agric Food Chem; 2012 Jan; 60(2):665-75. PubMed ID: 22148415
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Phenethyl isothiocyanate induces DNA damage-associated G2/M arrest and subsequent apoptosis in oral cancer cells with varying p53 mutations.
    Yeh YT; Yeh H; Su SH; Lin JS; Lee KJ; Shyu HW; Chen ZF; Huang SY; Su SJ
    Free Radic Biol Med; 2014 Sep; 74():1-13. PubMed ID: 24952138
    [TBL] [Abstract][Full Text] [Related]  

  • 37. [Cell cycle regulation after exposure to ionizing radiation].
    Teyssier F; Bay JO; Dionet C; Verrelle P
    Bull Cancer; 1999 Apr; 86(4):345-57. PubMed ID: 10341340
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells.
    Mak JP; Man WY; Chow JP; Ma HT; Poon RY
    Oncotarget; 2015 Aug; 6(25):21074-84. PubMed ID: 26025928
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dimethylfumarate inhibits melanoma cell proliferation via p21 and p53 induction and bcl-2 and cyclin B1 downregulation.
    Kaluzki I; Hrgovic I; Hailemariam-Jahn T; Doll M; Kleemann J; Valesky EM; Kippenberger S; Kaufmann R; Zoeller N; Meissner M
    Tumour Biol; 2016 Oct; 37(10):13627-13635. PubMed ID: 27468725
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Inhibition of checkpoint kinase 1 abrogates G2/M checkpoint activation and promotes apoptosis under heat stress.
    Furusawa Y; Iizumi T; Fujiwara Y; Zhao QL; Tabuchi Y; Nomura T; Kondo T
    Apoptosis; 2012 Jan; 17(1):102-12. PubMed ID: 22080164
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 86.