These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Microwave-assisted diastereoselective two-step three-component synthesis for rapid access to drug-like libraries of substituted 3-amino-β-lactams. Janssen GV; van den Heuvel JAC; Megens RP; Benningshof JCJ; Ovaa H Bioorg Med Chem; 2018 Jan; 26(1):41-49. PubMed ID: 29174508 [TBL] [Abstract][Full Text] [Related]
3. Synthesis of a stereochemically diverse library of medium-sized lactams and sultams via S(N)Ar cycloetherification. Gerard B; Duvall JR; Lowe JT; Murillo T; Wei J; Akella LB; Marcaurelle LA ACS Comb Sci; 2011 Jul; 13(4):365-74. PubMed ID: 21526820 [TBL] [Abstract][Full Text] [Related]
4. Synthesis of a library of "lead-like" γ-lactams by a one pot, four-component reaction. Martin KS; Di Maso MJ; Fettinger JC; Shaw JT ACS Comb Sci; 2013 Jul; 15(7):356-62. PubMed ID: 23682712 [TBL] [Abstract][Full Text] [Related]
5. One-pot synthesis of chiral α-methylene-γ-lactams with excellent diastereoselectivities and enantioselectivities. Shen A; Liu M; Jia ZS; Xu MH; Lin GQ Org Lett; 2010 Nov; 12(22):5154-7. PubMed ID: 20979375 [TBL] [Abstract][Full Text] [Related]
6. Microwave-assisted, divergent solution-phase synthesis of 1,3,6-trisubstituted pyrazolo[3,4-d]pyrimidines. Liu J; Wang X ACS Comb Sci; 2011 Jul; 13(4):414-20. PubMed ID: 21528879 [TBL] [Abstract][Full Text] [Related]
7. Stereoselective spirolactam synthesis via palladium catalyzed arylative allene carbocyclization cascades. Li M; Dixon DJ Org Lett; 2010 Sep; 12(17):3784-7. PubMed ID: 20698485 [TBL] [Abstract][Full Text] [Related]
8. Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods. Baumann M; Baxendale IR; Kuratli C; Ley SV; Martin RE; Schneider J ACS Comb Sci; 2011 Jul; 13(4):405-13. PubMed ID: 21528880 [TBL] [Abstract][Full Text] [Related]
9. Synthesis of 3,4-dihydropyridin-2(1H)-ones and 3,4-dihydro-2H-pyrans via Four-component reactions of aromatic aldehydes, cyclic 1,3-carbonyls, arylamines, and dimethyl acetylenedicarboxylate. Sun J; Xia EY; Wu Q; Yan CG ACS Comb Sci; 2011 Jul; 13(4):421-6. PubMed ID: 21568339 [TBL] [Abstract][Full Text] [Related]
10. Aminomethylhydroxylation of alkenes: Exploitation in the synthesis of scaffolds for small molecule libraries. Colomer I; Adeniji O; Burslem GM; Craven P; Rasmussen MO; Willaume A; Kalliokoski T; Foster R; Marsden SP; Nelson A Bioorg Med Chem; 2015 Jun; 23(11):2736-40. PubMed ID: 25740633 [TBL] [Abstract][Full Text] [Related]
11. Facile construction of structurally diverse thiazolidinedione-derived compounds via divergent stereoselective cascade organocatalysis and their biological exploratory studies. Zhang Y; Wang S; Wu S; Zhu S; Dong G; Miao Z; Yao J; Zhang W; Sheng C; Wang W ACS Comb Sci; 2013 Jun; 15(6):298-308. PubMed ID: 23614347 [TBL] [Abstract][Full Text] [Related]
12. Three-component one-pot approach to synthesize benzopyrano[4,3-d]pyrimidines. Li D; Duan S; Hu Y J Comb Chem; 2010 Nov; 12(6):895-9. PubMed ID: 20849089 [TBL] [Abstract][Full Text] [Related]
13. Synthesis of isoxazolo[5,4-b]pyridines by microwave-assisted multi-component reactions in water. Tu SJ; Zhang XH; Han ZG; Cao XD; Wu SS; Yan S; Hao WJ; Zhang G; Ma N J Comb Chem; 2009; 11(3):428-32. PubMed ID: 19364093 [TBL] [Abstract][Full Text] [Related]
14. Recent applications of olefin metathesis to combinatorial chemistry. Piscopio AD; Robinson JE Curr Opin Chem Biol; 2004 Jun; 8(3):245-54. PubMed ID: 15183322 [TBL] [Abstract][Full Text] [Related]
15. Synthesis of dibenzoxepine lactams via a Cu-catalyzed one-pot etherification/aldol condensation cascade reaction: application toward the total synthesis of aristoyagonine. Lim HS; Choi YL; Heo JN Org Lett; 2013 Sep; 15(18):4718-21. PubMed ID: 24000941 [TBL] [Abstract][Full Text] [Related]
16. Diastereoselective synthesis of gamma-lactams by a one-pot, four-component reaction. Wei J; Shaw JT Org Lett; 2007 Sep; 9(20):4077-80. PubMed ID: 17760458 [TBL] [Abstract][Full Text] [Related]
17. Enantioselective organocatalytic Friedel-Crafts alkylation reaction of indoles with 5-hydroxyfuran-2(5H)-one: access to chiral γ-lactones and γ-lactams via a Ugi 4-center 3-component reaction. Riguet E J Org Chem; 2011 Oct; 76(20):8143-50. PubMed ID: 21749090 [TBL] [Abstract][Full Text] [Related]