188 related articles for article (PubMed ID: 25686590)
1. Molecular design, synthesis and biological research of novel pyridyl acridones as potent DNA-binding and apoptosis-inducing agents.
Zhang B; Chen K; Wang N; Gao C; Sun Q; Li L; Chen Y; Tan C; Liu H; Jiang Y
Eur J Med Chem; 2015 Mar; 93():214-26. PubMed ID: 25686590
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and potent antileukemic activities of 10-benzyl-9(10H)-acridinones.
Gao C; Jiang Y; Tan C; Zu X; Liu H; Cao D
Bioorg Med Chem; 2008 Sep; 16(18):8670-5. PubMed ID: 18713666
[TBL] [Abstract][Full Text] [Related]
3. Acridone-pyrimidine hybrids- design, synthesis, cytotoxicity studies in resistant and sensitive cancer cells and molecular docking studies.
Murahari M; Prakash KV; Peters GJ; Mayur YC
Eur J Med Chem; 2017 Oct; 139():961-981. PubMed ID: 28886509
[TBL] [Abstract][Full Text] [Related]
4. Novel multi-substituted benzyl acridone derivatives as survivin inhibitors for hepatocellular carcinoma treatment.
Zhang B; Wang N; Zhang C; Gao C; Zhang W; Chen K; Wu W; Chen Y; Tan C; Liu F; Jiang Y
Eur J Med Chem; 2017 Mar; 129():337-348. PubMed ID: 28237663
[TBL] [Abstract][Full Text] [Related]
5. Design and synthesis of quinazolinone tagged acridones as cytotoxic agents and their effects on EGFR tyrosine kinase.
Babu YR; Bhagavanraju M; Reddy GD; Peters GJ; Prasad VV
Arch Pharm (Weinheim); 2014 Sep; 347(9):624-34. PubMed ID: 24866341
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological research of novel azaacridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.
Li D; Yuan Z; Chen S; Zhang C; Song L; Gao C; Chen Y; Tan C; Jiang Y
Bioorg Med Chem; 2017 Jul; 25(13):3437-3446. PubMed ID: 28511910
[TBL] [Abstract][Full Text] [Related]
7. Novel diindoloazepinone derivatives as DNA minor groove binding agents with selective topoisomerase I inhibition: Design, synthesis, biological evaluation and docking studies.
Kadagathur M; Devi GP; Grewal P; Sigalapalli DK; Makhal PN; Banerjee UC; Bathini NB; Tangellamudi ND
Bioorg Chem; 2020 Jun; 99():103629. PubMed ID: 32272367
[TBL] [Abstract][Full Text] [Related]
8. Structural optimizations and bioevaluation of N-substituted acridone derivatives as strong topoisomerase II inhibitors.
Li ZY; Xu GS; Song YL; Li X
Bioorg Chem; 2022 Feb; 119():105543. PubMed ID: 34929515
[TBL] [Abstract][Full Text] [Related]
9. Novel 4-(4-substituted amidobenzyl)furan-2(5H)-one derivatives as topoisomerase I inhibitors.
Peng CK; Zeng T; Xu XJ; Chang YQ; Hou W; Lu K; Lin H; Sun PH; Lin J; Chen WM
Eur J Med Chem; 2017 Feb; 127():187-199. PubMed ID: 28063351
[TBL] [Abstract][Full Text] [Related]
10. Pyridazino[1,6-b]quinazolinones as new anticancer scaffold: Synthesis, DNA intercalation, topoisomerase I inhibition and antitumor evaluation in vitro and in vivo.
Huang WY; Zhang XR; Lyu L; Wang SQ; Zhang XT
Bioorg Chem; 2020 Jun; 99():103814. PubMed ID: 32278208
[TBL] [Abstract][Full Text] [Related]
11. Structure-activity relationship of novel acridone derivatives as antiproliferative agents.
Chen JN; Wu XK; Lu CH; Li X
Bioorg Med Chem; 2021 Jan; 29():115868. PubMed ID: 33191085
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
[TBL] [Abstract][Full Text] [Related]
13. Novel synthetic acridine derivatives as potent DNA-binding and apoptosis-inducing antitumor agents.
Lang X; Li L; Chen Y; Sun Q; Wu Q; Liu F; Tan C; Liu H; Gao C; Jiang Y
Bioorg Med Chem; 2013 Jul; 21(14):4170-7. PubMed ID: 23735826
[TBL] [Abstract][Full Text] [Related]
14. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
Zhao W; Chen L; Li HM; Wang DJ; Li DS; Chen T; Yuan ZP; Tang YJ
Bioorg Med Chem; 2014 Jun; 22(11):2998-3007. PubMed ID: 24775914
[TBL] [Abstract][Full Text] [Related]
15. Synthesis of novel indole derivatives as promising DNA-binding agents and evaluation of antitumor and antitopoisomerase I activities.
Lafayette EA; de Almeida SMV; Cavalcanti Santos RV; de Oliveira JF; Amorim CADC; da Silva RMF; Pitta MGDR; Pitta IDR; de Moura RO; de Carvalho Júnior LB; de Melo Rêgo MJB; de Lima MDCA
Eur J Med Chem; 2017 Aug; 136():511-522. PubMed ID: 28531811
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and antiproliferative evaluation of fluorenone analogs with DNA topoisomerase I inhibitory properties.
Lee CC; Chang DM; Huang KF; Chen CL; Chen TC; Lo Y; Guh JH; Huang HS
Bioorg Med Chem; 2013 Nov; 21(22):7125-33. PubMed ID: 24094433
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and antitumor activity of non-camptothecin topoisomerase I inhibitors.
Zhang C; Li S; Ji L; Liu S; Li Z; Li S; Meng X
Bioorg Med Chem Lett; 2015 Oct; 25(20):4693-6. PubMed ID: 26384290
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, biological evaluation and virtual screening of some acridone derivatives as potential anticancer agents.
Oyedele AS; Bogan DN; Okoro CO
Bioorg Med Chem; 2020 May; 28(9):115426. PubMed ID: 32201193
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and biological evaluation of lapachol derivatives possessing indole scaffolds as topoisomerase I inhibitors.
Zhang C; Qu Y; Niu B
Bioorg Med Chem; 2016 Nov; 24(22):5781-5786. PubMed ID: 27667553
[TBL] [Abstract][Full Text] [Related]
20. Novel pyrazolo[3,4-d]pyrimidine with 4-(1H-benzimidazol-2-yl)-phenylamine as broad spectrum anticancer agents: Synthesis, cell based assay, topoisomerase inhibition, DNA intercalation and bovine serum albumin studies.
Singla P; Luxami V; Singh R; Tandon V; Paul K
Eur J Med Chem; 2017 Jan; 126():24-35. PubMed ID: 27744184
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
