BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

312 related articles for article (PubMed ID: 25702871)

  • 1. Molecular architecture of 4E-BP translational inhibitors bound to eIF4E.
    Peter D; Igreja C; Weber R; Wohlbold L; Weiler C; Ebertsch L; Weichenrieder O; Izaurralde E
    Mol Cell; 2015 Mar; 57(6):1074-1087. PubMed ID: 25702871
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4E-BPs require non-canonical 4E-binding motifs and a lateral surface of eIF4E to repress translation.
    Igreja C; Peter D; Weiler C; Izaurralde E
    Nat Commun; 2014 Sep; 5():4790. PubMed ID: 25179781
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
    Grüner S; Peter D; Weber R; Wohlbold L; Chung MY; Weichenrieder O; Valkov E; Igreja C; Izaurralde E
    Mol Cell; 2016 Nov; 64(3):467-479. PubMed ID: 27773676
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.
    Sekiyama N; Arthanari H; Papadopoulos E; Rodriguez-Mias RA; Wagner G; Léger-Abraham M
    Proc Natl Acad Sci U S A; 2015 Jul; 112(30):E4036-45. PubMed ID: 26170285
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
    Grüner S; Weber R; Peter D; Chung MY; Igreja C; Valkov E; Izaurralde E
    Nucleic Acids Res; 2018 Jul; 46(13):6893-6908. PubMed ID: 30053226
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G.
    Marcotrigiano J; Gingras AC; Sonenberg N; Burley SK
    Mol Cell; 1999 Jun; 3(6):707-16. PubMed ID: 10394359
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state.
    Ptushkina M; von der Haar T; Karim MM; Hughes JM; McCarthy JE
    EMBO J; 1999 Jul; 18(14):4068-75. PubMed ID: 10406811
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins.
    Niedzwiecka A; Marcotrigiano J; Stepinski J; Jankowska-Anyszka M; Wyslouch-Cieszynska A; Dadlez M; Gingras AC; Mak P; Darzynkiewicz E; Sonenberg N; Burley SK; Stolarski R
    J Mol Biol; 2002 Jun; 319(3):615-35. PubMed ID: 12054859
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification and function of the second eIF4E-binding region in N-terminal domain of eIF4G: comparison with eIF4E-binding protein.
    Umenaga Y; Paku KS; In Y; Ishida T; Tomoo K
    Biochem Biophys Res Commun; 2011 Oct; 414(3):462-7. PubMed ID: 21964297
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin.
    Korneeva NL; Song A; Gram H; Edens MA; Rhoads RE
    J Biol Chem; 2016 Feb; 291(7):3455-67. PubMed ID: 26668315
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitosis-related phosphorylation of the eukaryotic translation suppressor 4E-BP1 and its interaction with eukaryotic translation initiation factor 4E (eIF4E).
    Sun R; Cheng E; Velásquez C; Chang Y; Moore PS
    J Biol Chem; 2019 Aug; 294(31):11840-11852. PubMed ID: 31201269
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1.
    Connor JH; Lyles DS
    J Virol; 2002 Oct; 76(20):10177-87. PubMed ID: 12239292
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for mRNA Cap-Binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods.
    Tomoo K; Matsushita Y; Fujisaki H; Abiko F; Shen X; Taniguchi T; Miyagawa H; Kitamura K; Miura K; Ishida T
    Biochim Biophys Acta; 2005 Dec; 1753(2):191-208. PubMed ID: 16271312
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A unique binding mode of the eukaryotic translation initiation factor 4E for guiding the design of novel peptide inhibitors.
    Di Marino D; D'Annessa I; Tancredi H; Bagni C; Gallicchio E
    Protein Sci; 2015 Sep; 24(9):1370-82. PubMed ID: 26013047
    [TBL] [Abstract][Full Text] [Related]  

  • 15.
    Sekiyama N; Boeszoermenyi A; Arthanari H; Wagner G; Léger-Abraham M
    Biomol NMR Assign; 2017 Oct; 11(2):187-191. PubMed ID: 28589219
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural scaffold for eIF4E binding selectivity of 4E-BP isoforms: crystal structure of eIF4E binding region of 4E-BP2 and its comparison with that of 4E-BP1.
    Fukuyo A; In Y; Ishida T; Tomoo K
    J Pept Sci; 2011 Sep; 17(9):650-7. PubMed ID: 21661078
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation.
    Miras M; Truniger V; Silva C; Verdaguer N; Aranda MA; Querol-Audí J
    Plant Physiol; 2017 Jul; 174(3):1476-1491. PubMed ID: 28522457
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism.
    Gingras AC; Gygi SP; Raught B; Polakiewicz RD; Abraham RT; Hoekstra MF; Aebersold R; Sonenberg N
    Genes Dev; 1999 Jun; 13(11):1422-37. PubMed ID: 10364159
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The human eIF4E:4E-BP2 complex structure for studying hyperphosphorylation.
    Zeng J; Lu C; Huang X; Li Y
    Phys Chem Chem Phys; 2024 Apr; 26(14):10660-10672. PubMed ID: 38511550
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alterations in interprotein interactions between translation initiation factors assessed by fluorescence resonance energy transfer.
    Kimball SR; Horetsky RL
    Int J Biochem Cell Biol; 2001 Aug; 33(8):797-806. PubMed ID: 11404183
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.