1517 related articles for article (PubMed ID: 25706875)
1. Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.
Matano M; Date S; Shimokawa M; Takano A; Fujii M; Ohta Y; Watanabe T; Kanai T; Sato T
Nat Med; 2015 Mar; 21(3):256-62. PubMed ID: 25706875
[TBL] [Abstract][Full Text] [Related]
2. Chromosome Engineering of Human Colon-Derived Organoids to Develop a Model of Traditional Serrated Adenoma.
Kawasaki K; Fujii M; Sugimoto S; Ishikawa K; Matano M; Ohta Y; Toshimitsu K; Takahashi S; Hosoe N; Sekine S; Kanai T; Sato T
Gastroenterology; 2020 Feb; 158(3):638-651.e8. PubMed ID: 31622618
[TBL] [Abstract][Full Text] [Related]
3. Sequential cancer mutations in cultured human intestinal stem cells.
Drost J; van Jaarsveld RH; Ponsioen B; Zimberlin C; van Boxtel R; Buijs A; Sachs N; Overmeer RM; Offerhaus GJ; Begthel H; Korving J; van de Wetering M; Schwank G; Logtenberg M; Cuppen E; Snippert HJ; Medema JP; Kops GJ; Clevers H
Nature; 2015 May; 521(7550):43-7. PubMed ID: 25924068
[TBL] [Abstract][Full Text] [Related]
4. CRISPR-Cas9-mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes.
Takeda H; Kataoka S; Nakayama M; Ali MAE; Oshima H; Yamamoto D; Park JW; Takegami Y; An T; Jenkins NA; Copeland NG; Oshima M
Proc Natl Acad Sci U S A; 2019 Jul; 116(31):15635-15644. PubMed ID: 31300537
[TBL] [Abstract][Full Text] [Related]
5. Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis.
Nanki K; Toshimitsu K; Takano A; Fujii M; Shimokawa M; Ohta Y; Matano M; Seino T; Nishikori S; Ishikawa K; Kawasaki K; Togasaki K; Takahashi S; Sukawa Y; Ishida H; Sugimoto S; Kawakubo H; Kim J; Kitagawa Y; Sekine S; Koo BK; Kanai T; Sato T
Cell; 2018 Aug; 174(4):856-869.e17. PubMed ID: 30096312
[TBL] [Abstract][Full Text] [Related]
6. PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine.
Davies EJ; Marsh Durban V; Meniel V; Williams GT; Clarke AR
J Pathol; 2014 May; 233(1):27-38. PubMed ID: 24293351
[TBL] [Abstract][Full Text] [Related]
7. TP53 mutation at early stage of colorectal cancer progression from two types of laterally spreading tumors.
Sakai E; Fukuyo M; Matsusaka K; Ohata K; Doi N; Takane K; Matsuhashi N; Fukushima J; Nakajima A; Kaneda A
Cancer Sci; 2016 Jun; 107(6):820-7. PubMed ID: 26991699
[TBL] [Abstract][Full Text] [Related]
8. Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.
Artegiani B; van Voorthuijsen L; Lindeboom RGH; Seinstra D; Heo I; Tapia P; López-Iglesias C; Postrach D; Dayton T; Oka R; Hu H; van Boxtel R; van Es JH; Offerhaus J; Peters PJ; van Rheenen J; Vermeulen M; Clevers H
Cell Stem Cell; 2019 Jun; 24(6):927-943.e6. PubMed ID: 31130514
[TBL] [Abstract][Full Text] [Related]
9. Expression of R-Spondin 1 in Apc
Lähde M; Heino S; Högström J; Kaijalainen S; Anisimov A; Flanagan D; Kallio P; Leppänen VM; Ristimäki A; Ritvos O; Wu K; Tammela T; Hodder M; Sansom OJ; Alitalo K
Gastroenterology; 2021 Jan; 160(1):245-259. PubMed ID: 32941878
[TBL] [Abstract][Full Text] [Related]
10. RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.
Hilkens J; Timmer NC; Boer M; Ikink GJ; Schewe M; Sacchetti A; Koppens MAJ; Song JY; Bakker ERM
Gut; 2017 Jun; 66(6):1095-1105. PubMed ID: 27511199
[TBL] [Abstract][Full Text] [Related]
11. Somatic mutations of the APC, KRAS, and TP53 genes in nonpolypoid colorectal adenomas.
van Wyk R; Slezak P; Hayes VM; Buys CH; Kotze MJ; de Jong G; Rubio C; Dolk A; Jaramillo E; Koizumi K; Grobbelaar JJ
Genes Chromosomes Cancer; 2000 Feb; 27(2):202-8. PubMed ID: 10612810
[TBL] [Abstract][Full Text] [Related]
12. Colon Tumors with the Simultaneous Induction of Driver Mutations in APC, KRAS, and PIK3CA Still Progress through the Adenoma-to-carcinoma Sequence.
Hadac JN; Leystra AA; Paul Olson TJ; Maher ME; Payne SN; Yueh AE; Schwartz AR; Albrecht DM; Clipson L; Pasch CA; Matkowskyj KA; Halberg RB; Deming DA
Cancer Prev Res (Phila); 2015 Oct; 8(10):952-61. PubMed ID: 26276752
[TBL] [Abstract][Full Text] [Related]
13. Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer.
Lee DW; Han SW; Cha Y; Bae JM; Kim HP; Lyu J; Han H; Kim H; Jang H; Bang D; Huh I; Park T; Won JK; Jeong SY; Park KJ; Kang GH; Kim TY
Cancer; 2017 Sep; 123(18):3513-3523. PubMed ID: 28513830
[TBL] [Abstract][Full Text] [Related]
14. Ap4 is rate limiting for intestinal tumor formation by controlling the homeostasis of intestinal stem cells.
Jaeckel S; Kaller M; Jackstadt R; Götz U; Müller S; Boos S; Horst D; Jung P; Hermeking H
Nat Commun; 2018 Sep; 9(1):3573. PubMed ID: 30177706
[TBL] [Abstract][Full Text] [Related]
15. Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer.
Dietinger V; García de Durango CR; Wiechmann S; Boos SL; Michl M; Neumann J; Hermeking H; Kuster B; Jung P
Cell Commun Signal; 2020 Jun; 18(1):102. PubMed ID: 32586342
[TBL] [Abstract][Full Text] [Related]
16. Modeling Breast Cancer Using CRISPR-Cas9-Mediated Engineering of Human Breast Organoids.
Dekkers JF; Whittle JR; Vaillant F; Chen HR; Dawson C; Liu K; Geurts MH; Herold MJ; Clevers H; Lindeman GJ; Visvader JE
J Natl Cancer Inst; 2020 May; 112(5):540-544. PubMed ID: 31589320
[TBL] [Abstract][Full Text] [Related]
17. MET Signaling Mediates Intestinal Crypt-Villus Development, Regeneration, and Adenoma Formation and Is Promoted by Stem Cell CD44 Isoforms.
Joosten SPJ; Zeilstra J; van Andel H; Mijnals RC; Zaunbrecher J; Duivenvoorden AAM; van de Wetering M; Clevers H; Spaargaren M; Pals ST
Gastroenterology; 2017 Oct; 153(4):1040-1053.e4. PubMed ID: 28716720
[TBL] [Abstract][Full Text] [Related]
18. Frequent p53 gene mutations in serrated adenomas of the colorectum.
Hiyama T; Yokozaki H; Shimamoto F; Haruma K; Yasui W; Kajiyama G; Tahara E
J Pathol; 1998 Oct; 186(2):131-9. PubMed ID: 9924427
[TBL] [Abstract][Full Text] [Related]
19. Genetic reconstitution of tumorigenesis in primary intestinal cells.
Onuma K; Ochiai M; Orihashi K; Takahashi M; Imai T; Nakagama H; Hippo Y
Proc Natl Acad Sci U S A; 2013 Jul; 110(27):11127-32. PubMed ID: 23776211
[TBL] [Abstract][Full Text] [Related]
20. Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids.
Michels BE; Mosa MH; Streibl BI; Zhan T; Menche C; Abou-El-Ardat K; Darvishi T; Członka E; Wagner S; Winter J; Medyouf H; Boutros M; Farin HF
Cell Stem Cell; 2020 May; 26(5):782-792.e7. PubMed ID: 32348727
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
