BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1518 related articles for article (PubMed ID: 25706875)

  • 21. Quadruple-editing of the MAPK and PI3K pathways effectively blocks the progression of KRAS-mutated colorectal cancer cells.
    Wang Z; Kang B; Gao Q; Huang L; Di J; Fan Y; Yu J; Jiang B; Gao F; Wang D; Sun H; Gu Y; Li J; Su X
    Cancer Sci; 2021 Sep; 112(9):3895-3910. PubMed ID: 34185934
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression.
    Seino T; Kawasaki S; Shimokawa M; Tamagawa H; Toshimitsu K; Fujii M; Ohta Y; Matano M; Nanki K; Kawasaki K; Takahashi S; Sugimoto S; Iwasaki E; Takagi J; Itoi T; Kitago M; Kitagawa Y; Kanai T; Sato T
    Cell Stem Cell; 2018 Mar; 22(3):454-467.e6. PubMed ID: 29337182
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis.
    Smits R; Kartheuser A; Jagmohan-Changur S; Leblanc V; Breukel C; de Vries A; van Kranen H; van Krieken JH; Williamson S; Edelmann W; Kucherlapati R; KhanPM ; Fodde R
    Carcinogenesis; 1997 Feb; 18(2):321-7. PubMed ID: 9054624
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Toward recreating colon cancer in human organoids.
    Salahudeen AA; Kuo CJ
    Nat Med; 2015 Mar; 21(3):215-6. PubMed ID: 25742455
    [No Abstract]   [Full Text] [Related]  

  • 25. Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas.
    Shibata D; Schaeffer J; Li ZH; Capella G; Perucho M
    J Natl Cancer Inst; 1993 Jul; 85(13):1058-63. PubMed ID: 8515492
    [TBL] [Abstract][Full Text] [Related]  

  • 26. TRIB3 Interacts With β-Catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis.
    Hua F; Shang S; Yang YW; Zhang HZ; Xu TL; Yu JJ; Zhou DD; Cui B; Li K; Lv XX; Zhang XW; Liu SS; Yu JM; Wang F; Zhang C; Huang B; Hu ZW
    Gastroenterology; 2019 Feb; 156(3):708-721.e15. PubMed ID: 30365932
    [TBL] [Abstract][Full Text] [Related]  

  • 27. In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.
    Roper J; Tammela T; Cetinbas NM; Akkad A; Roghanian A; Rickelt S; Almeqdadi M; Wu K; Oberli MA; Sánchez-Rivera FJ; Park YK; Liang X; Eng G; Taylor MS; Azimi R; Kedrin D; Neupane R; Beyaz S; Sicinska ET; Suarez Y; Yoo J; Chen L; Zukerberg L; Katajisto P; Deshpande V; Bass AJ; Tsichlis PN; Lees J; Langer R; Hynes RO; Chen J; Bhutkar A; Jacks T; Yilmaz ÖH
    Nat Biotechnol; 2017 Jun; 35(6):569-576. PubMed ID: 28459449
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Mutations of the Apc gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats.
    De Filippo C; Caderni G; Bazzicalupo M; Briani C; Giannini A; Fazi M; Dolara P
    Br J Cancer; 1998 Jun; 77(12):2148-51. PubMed ID: 9649126
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mutation Status of
    Kawaguchi Y; Kopetz S; Newhook TE; De Bellis M; Chun YS; Tzeng CD; Aloia TA; Vauthey JN
    Clin Cancer Res; 2019 Oct; 25(19):5843-5851. PubMed ID: 31221662
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Combined Mutation of
    Sakai E; Nakayama M; Oshima H; Kouyama Y; Niida A; Fujii S; Ochiai A; Nakayama KI; Mimori K; Suzuki Y; Hong CP; Ock CY; Kim SJ; Oshima M
    Cancer Res; 2018 Mar; 78(5):1334-1346. PubMed ID: 29282223
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles.
    Yan HHN; Siu HC; Ho SL; Yue SSK; Gao Y; Tsui WY; Chan D; Chan AS; Wong JWH; Man AHY; Lee BCH; Chan ASY; Chan AKW; Hui HS; Cheung AKL; Law WL; Lo OSH; Yuen ST; Clevers H; Leung SY
    Gut; 2020 Dec; 69(12):2165-2179. PubMed ID: 32217638
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance.
    Ringel T; Frey N; Ringnalda F; Janjuha S; Cherkaoui S; Butz S; Srivatsa S; Pirkl M; Russo G; Villiger L; Rogler G; Clevers H; Beerenwinkel N; Zamboni N; Baubec T; Schwank G
    Cell Stem Cell; 2020 Mar; 26(3):431-440.e8. PubMed ID: 32142663
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.
    Steinhart Z; Pavlovic Z; Chandrashekhar M; Hart T; Wang X; Zhang X; Robitaille M; Brown KR; Jaksani S; Overmeer R; Boj SF; Adams J; Pan J; Clevers H; Sidhu S; Moffat J; Angers S
    Nat Med; 2017 Jan; 23(1):60-68. PubMed ID: 27869803
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Sequence of molecular genetic events in colorectal tumorigenesis.
    Laurent-Puig P; Blons H; Cugnenc PH
    Eur J Cancer Prev; 1999 Dec; 8 Suppl 1():S39-47. PubMed ID: 10772417
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mouse Models of Human Gastric Cancer Subtypes With Stomach-Specific CreERT2-Mediated Pathway Alterations.
    Seidlitz T; Chen YT; Uhlemann H; Schölch S; Kochall S; Merker SR; Klimova A; Hennig A; Schweitzer C; Pape K; Baretton GB; Welsch T; Aust DE; Weitz J; Koo BK; Stange DE
    Gastroenterology; 2019 Dec; 157(6):1599-1614.e2. PubMed ID: 31585123
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids.
    Fumagalli A; Drost J; Suijkerbuijk SJ; van Boxtel R; de Ligt J; Offerhaus GJ; Begthel H; Beerling E; Tan EH; Sansom OJ; Cuppen E; Clevers H; van Rheenen J
    Proc Natl Acad Sci U S A; 2017 Mar; 114(12):E2357-E2364. PubMed ID: 28270604
    [TBL] [Abstract][Full Text] [Related]  

  • 37. [Immunophenotypes and gene mutations in colorectal precancerous lesions and adenocarcinoma].
    Huang WT; Qiu T; Ling Y; Shi SS; Guo L; Zheng B; Lü N; Ying JM
    Zhonghua Bing Li Xue Za Zhi; 2013 Oct; 42(10):655-9. PubMed ID: 24433726
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A Transition Zone Showing Highly Discontinuous or Alternating Levels of Stem Cell and Proliferation Markers Characterizes the Development of PTEN-Haploinsufficient Colorectal Cancer.
    Arvai KJ; Hsu YH; Lee LA; Jones D
    PLoS One; 2015; 10(6):e0131108. PubMed ID: 26098881
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy.
    Clarke AR; Cummings MC; Harrison DJ
    Oncogene; 1995 Nov; 11(9):1913-20. PubMed ID: 7478622
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Modeling Wnt signaling by CRISPR-Cas9 genome editing recapitulates neoplasia in human Barrett epithelial organoids.
    Liu X; Cheng Y; Abraham JM; Wang Z; Wang Z; Ke X; Yan R; Shin EJ; Ngamruengphong S; Khashab MA; Zhang G; McNamara G; Ewald AJ; Lin D; Liu Z; Meltzer SJ
    Cancer Lett; 2018 Nov; 436():109-118. PubMed ID: 30144514
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 76.