These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 25709761)

  • 41. Study of human Orexin-1 and -2 G-protein-coupled receptors with novel and published antagonists by modeling, molecular dynamics simulations, and site-directed mutagenesis.
    Heifetz A; Morris GB; Biggin PC; Barker O; Fryatt T; Bentley J; Hallett D; Manikowski D; Pal S; Reifegerste R; Slack M; Law R
    Biochemistry; 2012 Apr; 51(15):3178-97. PubMed ID: 22448975
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Bridging molecular docking to membrane molecular dynamics to investigate GPCR-ligand recognition: the human A₂A adenosine receptor as a key study.
    Sabbadin D; Ciancetta A; Moro S
    J Chem Inf Model; 2014 Jan; 54(1):169-83. PubMed ID: 24359090
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Integrating Pharmacophore into Membrane Molecular Dynamics Simulations to Improve Homology Modeling of G Protein-coupled Receptors with Ligand Selectivity: A2A Adenosine Receptor as an Example.
    Zeng L; Guan M; Jin H; Liu Z; Zhang L
    Chem Biol Drug Des; 2015 Dec; 86(6):1438-50. PubMed ID: 26072970
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics.
    Vuckovic Z; Wang J; Pham V; Mobbs JI; Belousoff MJ; Bhattarai A; Burger WAC; Thompson G; Yeasmin M; Nawaratne V; Leach K; van der Westhuizen ET; Khajehali E; Liang YL; Glukhova A; Wootten D; Lindsley CW; Tobin A; Sexton P; Danev R; Valant C; Miao Y; Christopoulos A; Thal DM
    Elife; 2023 May; 12():. PubMed ID: 37248726
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Comparative modeling and docking of chemokine-receptor interactions with Rosetta.
    Wedemeyer MJ; Mueller BK; Bender BJ; Meiler J; Volkman BF
    Biochem Biophys Res Commun; 2020 Jul; 528(2):389-397. PubMed ID: 31924303
    [TBL] [Abstract][Full Text] [Related]  

  • 46. From heptahelical bundle to hits from the Haystack: structure-based virtual screening for GPCR ligands.
    Kooistra AJ; Roumen L; Leurs R; de Esch IJ; de Graaf C
    Methods Enzymol; 2013; 522():279-336. PubMed ID: 23374191
    [TBL] [Abstract][Full Text] [Related]  

  • 47. In Silico Drug Design for Purinergic GPCRs: Overview on Molecular Dynamics Applied to Adenosine and P2Y Receptors.
    Salmaso V; Jacobson KA
    Biomolecules; 2020 May; 10(6):. PubMed ID: 32466404
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Protein-water hydrogen-bond networks of G protein-coupled receptors: Graph-based analyses of static structures and molecular dynamics.
    Bertalan É; Lešnik S; Bren U; Bondar AN
    J Struct Biol; 2020 Dec; 212(3):107634. PubMed ID: 33007367
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Progress in studies of structure, mechanism and antagonists interaction of GPCR co-receptors for HIV.
    Zhong B; Zhen Y; Qin G; Yang H; Jiang H; Chen G; Yu K
    Curr Pharm Biotechnol; 2014; 15(10):938-50. PubMed ID: 25374029
    [TBL] [Abstract][Full Text] [Related]  

  • 50. How Do Molecular Dynamics Data Complement Static Structural Data of GPCRs.
    Torrens-Fontanals M; Stepniewski TM; Aranda-García D; Morales-Pastor A; Medel-Lacruz B; Selent J
    Int J Mol Sci; 2020 Aug; 21(16):. PubMed ID: 32824756
    [TBL] [Abstract][Full Text] [Related]  

  • 51. G protein-coupled receptor transmembrane binding pockets and their applications in GPCR research and drug discovery: a survey.
    Kratochwil NA; Gatti-McArthur S; Hoener MC; Lindemann L; Christ AD; Green LG; Guba W; Martin RE; Malherbe P; Porter RH; Slack JP; Winnig M; Dehmlow H; Grether U; Hertel C; Narquizian R; Panousis CG; Kolczewski S; Steward L
    Curr Top Med Chem; 2011; 11(15):1902-24. PubMed ID: 21470172
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Chemokines, chemokine receptors and small-molecule antagonists: recent developments.
    Onuffer JJ; Horuk R
    Trends Pharmacol Sci; 2002 Oct; 23(10):459-67. PubMed ID: 12368070
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Accelerated molecular dynamics simulations of the octopamine receptor using GPUs: discovery of an alternate agonist-binding position.
    Kastner KW; Izaguirre JA
    Proteins; 2016 Oct; 84(10):1480-9. PubMed ID: 27318014
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Structure network analysis to gain insights into GPCR function.
    Fanelli F; Felline A; Raimondi F; Seeber M
    Biochem Soc Trans; 2016 Apr; 44(2):613-8. PubMed ID: 27068978
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Improving the Modeling of Extracellular Ligand Binding Pockets in RosettaGPCR for Conformational Selection.
    Liessmann F; Künze G; Meiler J
    Int J Mol Sci; 2023 Apr; 24(9):. PubMed ID: 37175495
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Structural Characterization of Receptor-Receptor Interactions in the Allosteric Modulation of G Protein-Coupled Receptor (GPCR) Dimers.
    Lazim R; Suh D; Lee JW; Vu TNL; Yoon S; Choi S
    Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33810175
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Drug Repurposing on G Protein-Coupled Receptors Using a Computational Profiling Approach.
    de Felice A; Aureli S; Limongelli V
    Front Mol Biosci; 2021; 8():673053. PubMed ID: 34026848
    [TBL] [Abstract][Full Text] [Related]  

  • 58. High-level production, solubilization and purification of synthetic human GPCR chemokine receptors CCR5, CCR3, CXCR4 and CX3CR1.
    Ren H; Yu D; Ge B; Cook B; Xu Z; Zhang S
    PLoS One; 2009; 4(2):e4509. PubMed ID: 19223978
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Characterization of the dynamic events of GPCRs by automated computational simulations.
    Gutiérrez-de-Terán H; Bello X; Rodríguez D
    Biochem Soc Trans; 2013 Feb; 41(1):205-12. PubMed ID: 23356284
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Modeling the structural communication in supramolecular complexes involving GPCRs.
    Fanelli F
    Methods Mol Biol; 2012; 914():319-36. PubMed ID: 22976036
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.