These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 25709761)

  • 61. G-protein-coupled receptor-focused drug discovery using a target class platform approach.
    Heilker R; Wolff M; Tautermann CS; Bieler M
    Drug Discov Today; 2009 Mar; 14(5-6):231-40. PubMed ID: 19121411
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Strategies for improved modeling of GPCR-drug complexes: blind predictions of serotonin receptors bound to ergotamine.
    Rodríguez D; Ranganathan A; Carlsson J
    J Chem Inf Model; 2014 Jul; 54(7):2004-21. PubMed ID: 25030302
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Computational Workflow for Refining AlphaFold Models in Drug Design Using Kinetic and Thermodynamic Binding Calculations: A Case Study for the Unresolved Inactive Human Adenosine A
    Stampelou M; Ladds G; Kolocouris A
    J Phys Chem B; 2024 Feb; 128(4):914-936. PubMed ID: 38236582
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.
    Worth CL; Kleinau G; Krause G
    PLoS One; 2009 Sep; 4(9):e7011. PubMed ID: 19756152
    [TBL] [Abstract][Full Text] [Related]  

  • 65. GPCR homology model template selection benchmarking: Global versus local similarity measures.
    Castleman PN; Sears CK; Cole JA; Baker DL; Parrill AL
    J Mol Graph Model; 2019 Jan; 86():235-246. PubMed ID: 30390544
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Advances in Computational Techniques to Study GPCR-Ligand Recognition.
    Ciancetta A; Sabbadin D; Federico S; Spalluto G; Moro S
    Trends Pharmacol Sci; 2015 Dec; 36(12):878-890. PubMed ID: 26538318
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Recent Insights from Molecular Dynamics Simulations for G Protein-Coupled Receptor Drug Discovery.
    Zou Y; Ewalt J; Ng HL
    Int J Mol Sci; 2019 Aug; 20(17):. PubMed ID: 31470676
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Performance of virtual screening against GPCR homology models: Impact of template selection and treatment of binding site plasticity.
    Jaiteh M; Rodríguez-Espigares I; Selent J; Carlsson J
    PLoS Comput Biol; 2020 Mar; 16(3):e1007680. PubMed ID: 32168319
    [TBL] [Abstract][Full Text] [Related]  

  • 69. The role of water in activation mechanism of human N-formyl peptide receptor 1 (FPR1) based on molecular dynamics simulations.
    Yuan S; Ghoshdastider U; Trzaskowski B; Latek D; Debinski A; Pulawski W; Wu R; Gerke V; Filipek S
    PLoS One; 2012; 7(11):e47114. PubMed ID: 23189124
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Mechanism of the G-protein mimetic nanobody binding to a muscarinic G-protein-coupled receptor.
    Miao Y; McCammon JA
    Proc Natl Acad Sci U S A; 2018 Mar; 115(12):3036-3041. PubMed ID: 29507218
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Using molecular dynamics for the refinement of atomistic models of GPCRs by homology modeling.
    Lupala CS; Rasaeifar B; Gomez-Gutierrez P; Perez JJ
    J Biomol Struct Dyn; 2018 Jul; 36(9):2436-2448. PubMed ID: 28728517
    [TBL] [Abstract][Full Text] [Related]  

  • 72. G-Protein coupled receptors: answers from simulations.
    Clark T
    Beilstein J Org Chem; 2017; 13():1071-1078. PubMed ID: 28684986
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Exploring GPCR-Lipid Interactions by Molecular Dynamics Simulations: Excitements, Challenges, and the Way Forward.
    Sengupta D; Prasanna X; Mohole M; Chattopadhyay A
    J Phys Chem B; 2018 Jun; 122(22):5727-5737. PubMed ID: 29685028
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Molecular modeling of vasopressin receptor and in silico screening of V1b receptor antagonists.
    Hagiwara Y; Ohno K; Kamohara M; Takasaki J; Watanabe T; Fukunishi Y; Nakamura H; Orita M
    Expert Opin Drug Discov; 2013 Aug; 8(8):951-64. PubMed ID: 23682717
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Quantitative and systems pharmacology 2. In silico polypharmacology of G protein-coupled receptor ligands via network-based approaches.
    Wu Z; Lu W; Yu W; Wang T; Li W; Liu G; Zhang H; Pang X; Huang J; Liu M; Cheng F; Tang Y
    Pharmacol Res; 2018 Mar; 129():400-413. PubMed ID: 29133212
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function.
    Kristiansen K
    Pharmacol Ther; 2004 Jul; 103(1):21-80. PubMed ID: 15251227
    [TBL] [Abstract][Full Text] [Related]  

  • 77. New Trends in Inspecting GPCR-ligand Recognition Process: the Contribution of the Molecular Modeling Section (MMS) at the University of Padova.
    Ciancetta A; Cuzzolin A; Deganutti G; Sturlese M; Salmaso V; Cristiani A; Sabbadin D; Moro S
    Mol Inform; 2016 Sep; 35(8-9):440-8. PubMed ID: 27546048
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Dynamic States of the Ligand-Free Class A G Protein-Coupled Receptor Extracellular Side.
    Zhang Q; Zhou M; Zhao L; Jiang H; Yang H
    Biochemistry; 2018 Aug; 57(32):4767-4775. PubMed ID: 29999306
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Molecular Basis of Ligand Dissociation from G Protein-Coupled Receptors and Predicting Residence Time.
    Guo D; IJzerman AP
    Methods Mol Biol; 2018; 1705():197-206. PubMed ID: 29188564
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora's box for novel drug discovery?
    Filizola M
    Life Sci; 2010 Apr; 86(15-16):590-7. PubMed ID: 19465029
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.