BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 25711379)

  • 1. Dynamic hydrogen bonding and DNA flexibility in minor groove binders: molecular dynamics simulation of the polyamide f-ImPyIm bound to the Mlu1 (MCB) sequence 5'-ACGCGT-3' in 2:1 motif.
    Bruce CD; Ferrara MM; Manka JL; Davis ZS; Register J
    J Mol Recognit; 2015 May; 28(5):325-37. PubMed ID: 25711379
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sequence recognition in the minor groove of DNA by covalently linked formamido imidazole-pyrrole-imidazole polyamides: effect of H-pin linkage and linker length on selectivity and affinity.
    O'Hare CC; Uthe P; Mackay H; Blackmon K; Jones J; Brown T; Nguyen B; Wilson WD; Lee M; Hartley JA
    Biochemistry; 2007 Oct; 46(42):11661-70. PubMed ID: 17910471
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Physical and structural basis for the strong interactions of the -ImPy- central pairing motif in the polyamide f-ImPyIm.
    Buchmueller KL; Bailey SL; Matthews DA; Taherbhai ZT; Register JK; Davis ZS; Bruce CD; O'Hare C; Hartley JA; Lee M
    Biochemistry; 2006 Nov; 45(45):13551-65. PubMed ID: 17087509
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Setting anchor in the minor groove: in silico investigation into formamido N-methylpyrrole and N-methylimidazole polyamides bound by cognate DNA sequences.
    Collar CJ; Lee M; Wilson WD
    J Chem Inf Model; 2010 Sep; 50(9):1611-22. PubMed ID: 20804157
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modifying the N-terminus of polyamides: PyImPyIm has improved sequence specificity over f-ImPyIm.
    Brown T; Mackay H; Turlington M; Sutterfield A; Smith T; Sielaff A; Westrate L; Bruce C; Kluza J; O'Hare C; Nguyen B; Wilson WD; Hartley JA; Lee M
    Bioorg Med Chem; 2008 May; 16(9):5266-76. PubMed ID: 18353654
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studies.
    Mackay H; Brown T; Uthe PB; Westrate L; Sielaff A; Jones J; Lajiness JP; Kluza J; O'Hare C; Nguyen B; Davis Z; Bruce C; Wilson WD; Hartley JA; Lee M
    Bioorg Med Chem; 2008 Oct; 16(20):9145-53. PubMed ID: 18819814
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Solution structure of the calicheamicin gamma 1I-DNA complex.
    Kumar RA; Ikemoto N; Patel DJ
    J Mol Biol; 1997 Jan; 265(2):187-201. PubMed ID: 9020982
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel diamino imidazole and pyrrole-containing polyamides: Synthesis and DNA binding studies of mono- and diamino-phenyl-ImPy*Im polyamides designed to target 5'-ACGCGT-3'.
    Satam V; Babu B; Chavda S; Savagian M; Sjoholm R; Tzou S; Ramos J; Liu Y; Kiakos K; Lin S; David Wilson W; Hartley JA; Lee M
    Bioorg Med Chem; 2012 Jan; 20(2):693-701. PubMed ID: 22222156
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular dynamics simulations of A. T-rich oligomers: sequence-specific binding of Na+ in the minor groove of B-DNA.
    Mocci F; Saba G
    Biopolymers; 2003 Apr; 68(4):471-85. PubMed ID: 12666173
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of the N-terminal acylamido group of imidazole- and pyrrole-containing polyamides on DNA sequence specificity and binding affinity.
    Westrate L; Mackay H; Brown T; Nguyen B; Kluza J; Wilson WD; Lee M; Hartley JA
    Biochemistry; 2009 Jun; 48(24):5679-88. PubMed ID: 19419200
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and DNA binding properties of 1-(3-aminopropyl)-imidazole-containing triamide f-Im*PyIm: a novel diamino polyamide designed to target 5'-ACGCGT-3'.
    Satam V; Babu B; Porte A; Savagian M; Lee M; Smeltzer T; Liu Y; Ramos J; Wilson WD; Lin S; Kiakos K; Hartley JA; Lee M
    Bioorg Med Chem Lett; 2012 Sep; 22(18):5898-902. PubMed ID: 22892118
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular dynamics simulations and free energy calculations of netropsin and distamycin binding to an AAAAA DNA binding site.
    Dolenc J; Oostenbrink C; Koller J; van Gunsteren WF
    Nucleic Acids Res; 2005; 33(2):725-33. PubMed ID: 15687382
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular recognition of DNA base pairs by the formamido/pyrrole and formamido/imidazole pairings in stacked polyamides.
    Buchmueller KL; Staples AM; Uthe PB; Howard CM; Pacheco KA; Cox KK; Henry JA; Bailey SL; Horick SM; Nguyen B; Wilson WD; Lee M
    Nucleic Acids Res; 2005; 33(3):912-21. PubMed ID: 15703305
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biophysical evaluation of minor-groove binding C-terminus modified pyrrole and imidazole triamide analogs of distamycin.
    Brown T; Taherbhai Z; Sexton J; Sutterfield A; Turlington M; Jones J; Stallings L; Stewart M; Buchmueller K; Mackay H; O'hare C; Kluza J; Nguyen B; Wilson D; Lee M; Hartley JA
    Bioorg Med Chem; 2007 Jan; 15(1):474-83. PubMed ID: 17035029
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Binding of AR-1-144, a tri-imidazole DNA minor groove binder, to CCGG sequence analyzed by NMR spectroscopy.
    Yang XL; Kaenzig C; Lee M; Wang AH
    Eur J Biochem; 1999 Aug; 263(3):646-55. PubMed ID: 10469127
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular modelling of the interaction of carbocyclic analogues of netropsin and distamycin with d(CGCGAATTCGCG)2.
    Bielawski K; Bielawska A; Bartulewicz D; Rózański A
    Acta Biochim Pol; 2000; 47(3):855-66. PubMed ID: 11310985
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Search for the optimal linker in tandem hairpin polyamides.
    Kers I; Dervan PB
    Bioorg Med Chem; 2002 Oct; 10(10):3339-49. PubMed ID: 12150881
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components.
    Padroni G; Withers JM; Taladriz-Sender A; Reichenbach LF; Parkinson JA; Burley GA
    J Am Chem Soc; 2019 Jun; 141(24):9555-9563. PubMed ID: 31117639
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design of a G.C-specific DNA minor groove-binding peptide.
    Geierstanger BH; Mrksich M; Dervan PB; Wemmer DE
    Science; 1994 Oct; 266(5185):646-50. PubMed ID: 7939719
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and hydration of BamHI DNA recognition site: a molecular dynamics investigation.
    Castrignanò T; Chillemi G; Desideri A
    Biophys J; 2000 Sep; 79(3):1263-72. PubMed ID: 10968990
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.