BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

348 related articles for article (PubMed ID: 25713061)

  • 1. Key residues in the nicotinic acetylcholine receptor β2 subunit contribute to α-conotoxin LvIA binding.
    Zhangsun D; Zhu X; Wu Y; Hu Y; Kaas Q; Craik DJ; McIntosh JM; Luo S
    J Biol Chem; 2015 Apr; 290(15):9855-62. PubMed ID: 25713061
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel α4/7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors.
    Luo S; Zhangsun D; Schroeder CI; Zhu X; Hu Y; Wu Y; Weltzin MM; Eberhard S; Kaas Q; Craik DJ; McIntosh JM; Whiteaker P
    FASEB J; 2014 Apr; 28(4):1842-53. PubMed ID: 24398291
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins.
    Cuny H; Kompella SN; Tae HS; Yu R; Adams DJ
    J Biol Chem; 2016 Nov; 291(45):23779-23792. PubMed ID: 27646000
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the alpha3beta2 nicotinic receptor.
    Luo S; Akondi KB; Zhangsun D; Wu Y; Zhu X; Hu Y; Christensen S; Dowell C; Daly NL; Craik DJ; Wang CI; Lewis RJ; Alewood PF; Michael McIntosh J
    J Biol Chem; 2010 Apr; 285(16):12355-66. PubMed ID: 20145249
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High Selectivity of an α-Conotoxin LvIA Analogue for α3β2 Nicotinic Acetylcholine Receptors Is Mediated by β2 Functionally Important Residues.
    Zhu X; Pan S; Xu M; Zhang L; Yu J; Yu J; Wu Y; Fan Y; Li H; Kasheverov IE; Kudryavtsev DS; Tsetlin VI; Xue Y; Zhangsun D; Wang X; Luo S
    J Med Chem; 2020 Nov; 63(22):13656-13668. PubMed ID: 33196189
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Basic Residues at Position 11 of α-Conotoxin LvIA Influence Subtype Selectivity between α3β2 and α3β4 Nicotinic Receptors via an Electrostatic Mechanism.
    Haufe Y; Kuruva V; Samanani Z; Lokaj G; Kamnesky G; Shadamarshan P; Shahoei R; Katz D; Sampson JM; Pusch M; Brik A; Nicke A; Leffler AE
    ACS Chem Neurosci; 2023 Dec; 14(24):4311-4322. PubMed ID: 38051211
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Beta2 subunit contribution to 4/7 alpha-conotoxin binding to the nicotinic acetylcholine receptor.
    Dutertre S; Nicke A; Lewis RJ
    J Biol Chem; 2005 Aug; 280(34):30460-8. PubMed ID: 15929983
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Acetylcholine promotes binding of α-conotoxin MII at α3 β2 nicotinic acetylcholine receptors.
    Sambasivarao SV; Roberts J; Bharadwaj VS; Slingsby JG; Rohleder C; Mallory C; Groome JR; McDougal OM; Maupin CM
    Chembiochem; 2014 Feb; 15(3):413-24. PubMed ID: 24420650
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The crystal structure of Ac-AChBP in complex with α-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes.
    Xu M; Zhu X; Yu J; Yu J; Luo S; Wang X
    Protein Cell; 2017 Sep; 8(9):675-685. PubMed ID: 28585176
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potency- and Selectivity-Enhancing Mutations of Conotoxins for Nicotinic Acetylcholine Receptors Can Be Predicted Using Accurate Free-Energy Calculations.
    Katz D; DiMattia MA; Sindhikara D; Li H; Abraham N; Leffler AE
    Mar Drugs; 2021 Jun; 19(7):. PubMed ID: 34202022
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Efficient binding of 4/7 α-conotoxins to nicotinic α4β2 receptors is prevented by Arg185 and Pro195 in the α4 subunit.
    Beissner M; Dutertre S; Schemm R; Danker T; Sporning A; Grubmüller H; Nicke A
    Mol Pharmacol; 2012 Oct; 82(4):711-8. PubMed ID: 22802270
    [TBL] [Abstract][Full Text] [Related]  

  • 12. α-Conotoxins Identify the α3β4* Subtype as the Predominant Nicotinic Acetylcholine Receptor Expressed in Human Adrenal Chromaffin Cells.
    Hone AJ; McIntosh JM; Azam L; Lindstrom J; Lucero L; Whiteaker P; Passas J; Blázquez J; Albillos A
    Mol Pharmacol; 2015 Nov; 88(5):881-93. PubMed ID: 26330550
    [TBL] [Abstract][Full Text] [Related]  

  • 13. α-Conotoxin Bt1.8 from Conus betulinus selectively inhibits α6/α3β2β3 and α3β2 nicotinic acetylcholine receptor subtypes.
    Ning H; Huang B; Tae HS; Liu Z; Yu S; Li L; Zhang L; Adams DJ; Guo C; Dai Q
    J Neurochem; 2021 Oct; 159(1):90-100. PubMed ID: 34008858
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Determinants of alpha-conotoxin BuIA selectivity on the nicotinic acetylcholine receptor beta subunit.
    Shiembob DL; Roberts RL; Luetje CW; McIntosh JM
    Biochemistry; 2006 Sep; 45(37):11200-7. PubMed ID: 16964981
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors.
    Grishin AA; Cuny H; Hung A; Clark RJ; Brust A; Akondi K; Alewood PF; Craik DJ; Adams DJ
    J Biol Chem; 2013 Nov; 288(48):34428-42. PubMed ID: 24100032
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alpha-conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as alpha3beta2 and alpha7 nicotinic acetylcholine receptors.
    Talley TT; Olivera BM; Han KH; Christensen SB; Dowell C; Tsigelny I; Ho KY; Taylor P; McIntosh JM
    J Biol Chem; 2006 Aug; 281(34):24678-86. PubMed ID: 16803900
    [TBL] [Abstract][Full Text] [Related]  

  • 17. α-Conotoxin VnIB from Conus ventricosus is a potent and selective antagonist of α6β4* nicotinic acetylcholine receptors.
    van Hout M; Valdes A; Christensen SB; Tran PT; Watkins M; Gajewiak J; Jensen AA; Olivera BM; McIntosh JM
    Neuropharmacology; 2019 Oct; 157():107691. PubMed ID: 31255696
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular docking study on the α3β2 neuronal nicotinic acetylcholine receptor complexed with α-conotoxin GIC.
    Lee C; Lee SH; Kim DH; Han KH
    BMB Rep; 2012 May; 45(5):275-80. PubMed ID: 22617450
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amino acid residues that confer high selectivity of the alpha6 nicotinic acetylcholine receptor subunit to alpha-conotoxin MII[S4A,E11A,L15A].
    Azam L; Yoshikami D; McIntosh JM
    J Biol Chem; 2008 Apr; 283(17):11625-32. PubMed ID: 18299323
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular determinants of α-conotoxin potency for inhibition of human and rat α6β4 nicotinic acetylcholine receptors.
    Hone AJ; Talley TT; Bobango J; Huidobro Melo C; Hararah F; Gajewiak J; Christensen S; Harvey PJ; Craik DJ; McIntosh JM
    J Biol Chem; 2018 Nov; 293(46):17838-17852. PubMed ID: 30249616
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.