These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 25715695)

  • 1. Quantitative Evaluation of mMate1 Function Based on Minimally Invasive Measurement of Tissue Concentration Using PET with [(11)C]Metformin in Mouse.
    Shingaki T; Hume WE; Takashima T; Katayama Y; Okauchi T; Hayashinaka E; Wada Y; Cui Y; Kusuhara H; Sugiyama Y; Watanabe Y
    Pharm Res; 2015 Aug; 32(8):2538-47. PubMed ID: 25715695
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine.
    Ito S; Kusuhara H; Kuroiwa Y; Wu C; Moriyama Y; Inoue K; Kondo T; Yuasa H; Nakayama H; Horita S; Sugiyama Y
    J Pharmacol Exp Ther; 2010 Apr; 333(1):341-50. PubMed ID: 20065018
    [TBL] [Abstract][Full Text] [Related]  

  • 3. N(1)-methylnicotinamide as an endogenous probe for drug interactions by renal cation transporters: studies on the metformin-trimethoprim interaction.
    Müller F; Pontones CA; Renner B; Mieth M; Hoier E; Auge D; Maas R; Zolk O; Fromm MF
    Eur J Clin Pharmacol; 2015 Jan; 71(1):85-94. PubMed ID: 25552403
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibitory effect of atenolol on urinary excretion of metformin via down-regulating multidrug and toxin extrusion protein 1 (rMate1) expression in the kidney of rats.
    Ma YR; Huang J; Shao YY; Ma K; Zhang GQ; Zhou Y; Zhi R; Qin HY; Wu XA
    Eur J Pharm Sci; 2015 Feb; 68():18-26. PubMed ID: 25486332
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The synthesis and biodistribution of [(11)C]metformin as a PET probe to study hepatobiliary transport mediated by the multi-drug and toxin extrusion transporter 1 (MATE1) in vivo.
    Hume WE; Shingaki T; Takashima T; Hashizume Y; Okauchi T; Katayama Y; Hayashinaka E; Wada Y; Kusuhara H; Sugiyama Y; Watanabe Y
    Bioorg Med Chem; 2013 Dec; 21(24):7584-90. PubMed ID: 24238901
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A PET Tracer for Renal Organic Cation Transporters, ¹¹C-Metformin: Radiosynthesis and Preclinical Proof-of-Concept Studies.
    Jakobsen S; Busk M; Jensen JB; Munk OL; Zois NE; Alstrup AK; Jessen N; Frøkiær J
    J Nucl Med; 2016 Apr; 57(4):615-21. PubMed ID: 26769859
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Organic cation transporter and multidrug and toxin extrusion 1 co-mediated interaction between metformin and berberine.
    Shi R; Xu Z; Xu X; Jin J; Zhao Y; Wang T; Li Y; Ma Y
    Eur J Pharm Sci; 2019 Jan; 127():282-290. PubMed ID: 30428337
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [11C]-Labeled Metformin Distribution in the Liver and Small Intestine Using Dynamic Positron Emission Tomography in Mice Demonstrates Tissue-Specific Transporter Dependency.
    Jensen JB; Sundelin EI; Jakobsen S; Gormsen LC; Munk OL; Frøkiær J; Jessen N
    Diabetes; 2016 Jun; 65(6):1724-30. PubMed ID: 26993065
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of the multidrug and toxin extrusion (MATE) transporter by pyrimethamine increases the plasma concentration of metformin but does not increase antihyperglycaemic activity in humans.
    Oh J; Chung H; Park SI; Yi SJ; Jang K; Kim AH; Yoon J; Cho JY; Yoon SH; Jang IJ; Yu KS; Chung JY
    Diabetes Obes Metab; 2016 Jan; 18(1):104-8. PubMed ID: 26381793
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of Oatp and Mrp2 activities in hepatobiliary excretion using newly developed positron emission tomography tracer [11C]dehydropravastatin in rats.
    Shingaki T; Takashima T; Ijuin R; Zhang X; Onoue T; Katayama Y; Okauchi T; Hayashinaka E; Cui Y; Wada Y; Suzuki M; Maeda K; Kusuhara H; Sugiyama Y; Watanabe Y
    J Pharmacol Exp Ther; 2013 Oct; 347(1):193-202. PubMed ID: 23926287
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Clinical Quantitative Evaluation of Hepatobiliary Transport of [
    Kaneko K; Tanaka M; Ishii A; Katayama Y; Nakaoka T; Irie S; Kawahata H; Yamanaga T; Wada Y; Miyake T; Toshimoto K; Maeda K; Cui Y; Enomoto M; Kawamura E; Kawada N; Kawabe J; Shiomi S; Kusuhara H; Sugiyama Y; Watanabe Y
    Drug Metab Dispos; 2018 May; 46(5):719-728. PubMed ID: 29555827
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of high uric acid on the disposition of metformin: in vivo and in vitro studies.
    Zhang G; Ma Y; Xi D; Rao Z; Sun X; Wu X
    Biopharm Drug Dispos; 2019 Jan; 40(1):3-11. PubMed ID: 30488476
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeted disruption of the multidrug and toxin extrusion 1 (mate1) gene in mice reduces renal secretion of metformin.
    Tsuda M; Terada T; Mizuno T; Katsura T; Shimakura J; Inui K
    Mol Pharmacol; 2009 Jun; 75(6):1280-6. PubMed ID: 19332510
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Different effect of testosterone and oestrogen on urinary excretion of metformin via regulating OCTs and MATEs expression in the kidney of mice.
    He R; Ai L; Zhang D; Wan L; Zheng T; Yin J; Lu H; Lu J; Lu F; Liu F; Jia W
    J Cell Mol Med; 2016 Dec; 20(12):2309-2317. PubMed ID: 27469532
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pregnancy Increases the Renal Secretion of N
    Bergagnini-Kolev MC; Hebert MF; Easterling TR; Lin YS
    Drug Metab Dispos; 2017 Mar; 45(3):325-329. PubMed ID: 28069720
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Practical Synthesis of [
    Nakaoka T; Uetake Y; Kaneko KI; Niwa T; Ochiai H; Irie S; Suezaki Y; Otsuka N; Hayashinaka E; Wada Y; Cui Y; Maeda K; Kusuhara H; Sugiyama Y; Hosoya T; Watanabe Y
    Mol Pharm; 2020 Jun; 17(6):1884-1898. PubMed ID: 32271581
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of a MATE protein inhibitor, pyrimethamine, on the renal elimination of metformin at oral microdose and at therapeutic dose in healthy subjects.
    Kusuhara H; Ito S; Kumagai Y; Jiang M; Shiroshita T; Moriyama Y; Inoue K; Yuasa H; Sugiyama Y
    Clin Pharmacol Ther; 2011 Jun; 89(6):837-44. PubMed ID: 21544077
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions.
    Burt HJ; Neuhoff S; Almond L; Gaohua L; Harwood MD; Jamei M; Rostami-Hodjegan A; Tucker GT; Rowland-Yeo K
    Eur J Pharm Sci; 2016 Jun; 88():70-82. PubMed ID: 27019345
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein-Mediated Drug-Drug Interactions in Healthy Volunteers.
    Miyake T; Kimoto E; Luo L; Mathialagan S; Horlbogen LM; Ramanathan R; Wood LS; Johnson JG; Le VH; Vourvahis M; Rodrigues AD; Muto C; Furihata K; Sugiyama Y; Kusuhara H
    Clin Pharmacol Ther; 2021 Feb; 109(2):507-516. PubMed ID: 32866300
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism of Altered Metformin Distribution in Nonalcoholic Steatohepatitis.
    Clarke JD; Dzierlenga AL; Nelson NR; Li H; Werts S; Goedken MJ; Cherrington NJ
    Diabetes; 2015 Sep; 64(9):3305-13. PubMed ID: 26016715
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.