These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 25725286)

  • 1. EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells.
    Sidarala V; Veluthakal R; Syeda K; Kowluru A
    Cell Signal; 2015 Jun; 27(6):1159-67. PubMed ID: 25725286
    [TBL] [Abstract][Full Text] [Related]  

  • 2. VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells.
    Veluthakal R; Tunduguru R; Arora DK; Sidarala V; Syeda K; Vlaar CP; Thurmond DC; Kowluru A
    Diabetologia; 2015 Nov; 58(11):2573-81. PubMed ID: 26224100
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.
    Kowluru A; Veluthakal R; Rhodes CJ; Kamath V; Syed I; Koch BJ
    Diabetes; 2010 Apr; 59(4):967-77. PubMed ID: 20071600
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets.
    Jayaram B; Syed I; Kyathanahalli CN; Rhodes CJ; Kowluru A
    Biochem Pharmacol; 2011 Apr; 81(8):1016-27. PubMed ID: 21276423
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1).
    Sidarala V; Veluthakal R; Syeda K; Vlaar C; Newsholme P; Kowluru A
    Biochem Pharmacol; 2015 Jun; 95(4):301-10. PubMed ID: 25881746
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exposure to chronic hyperglycemic conditions results in Ras-related C3 botulinum toxin substrate 1 (Rac1)-mediated activation of p53 and ATM kinase in pancreatic β-cells.
    Sidarala V; Kowluru A
    Apoptosis; 2017 May; 22(5):597-607. PubMed ID: 28220272
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Paradoxical regulation of glucose-induced Rac1 activation and insulin secretion by RhoGDIβ in pancreatic β-cells.
    Thamilselvan V; Kowluru A
    Small GTPases; 2021 Mar; 12(2):114-121. PubMed ID: 31267831
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nm23-H1 regulates glucose-stimulated insulin secretion in pancreatic β-cells via Arf6-Rac1 signaling axis.
    Veluthakal R; Kaetzel D; Kowluru A
    Cell Physiol Biochem; 2013; 32(3):533-41. PubMed ID: 24008651
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cells.
    Veluthakal R; Madathilparambil SV; McDonald P; Olson LK; Kowluru A
    Biochem Pharmacol; 2009 Jan; 77(1):101-13. PubMed ID: 18930714
    [TBL] [Abstract][Full Text] [Related]  

  • 10. P-Rex1 Mediates Glucose-Stimulated Rac1 Activation and Insulin Secretion in Pancreatic β-Cells.
    Thamilselvan V; Gamage S; Harajli A; Chundru SA; Kowluru A
    Cell Physiol Biochem; 2020 Dec; 54(6):1218-1230. PubMed ID: 33347743
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin.
    Asahara S; Shibutani Y; Teruyama K; Inoue HY; Kawada Y; Etoh H; Matsuda T; Kimura-Koyanagi M; Hashimoto N; Sakahara M; Fujimoto W; Takahashi H; Ueda S; Hosooka T; Satoh T; Inoue H; Matsumoto M; Aiba A; Kasuga M; Kido Y
    Diabetologia; 2013 May; 56(5):1088-97. PubMed ID: 23412604
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The adaptor protein APPL2 controls glucose-stimulated insulin secretion via F-actin remodeling in pancreatic β-cells.
    Wang B; Lin H; Li X; Lu W; Kim JB; Xu A; Cheng KKY
    Proc Natl Acad Sci U S A; 2020 Nov; 117(45):28307-28315. PubMed ID: 33122440
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phagocytic NADPH oxidase links ARNO-Arf6 signaling pathway in glucose-stimulated insulin secretion from the pancreatic β-cell.
    Jayaram B; Kowluru A
    Cell Physiol Biochem; 2012; 30(6):1351-62. PubMed ID: 23095975
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Friendly, and not so friendly, roles of Rac1 in islet β-cell function: lessons learnt from pharmacological and molecular biological approaches.
    Kowluru A
    Biochem Pharmacol; 2011 Apr; 81(8):965-75. PubMed ID: 21300027
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hyperglycemic Conditions Promote Rac1-Mediated Serine536 Phosphorylation of p65 Subunit of NFκB (RelA) in Pancreatic Beta Cells.
    Kowluru A; Gamage S; Hali M; Gleason N
    Cell Physiol Biochem; 2022 Aug; 56(4):367-381. PubMed ID: 35981264
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RhoG-Rac1 Signaling Pathway Mediates Metabolic Dysfunction of the Pancreatic Beta-Cells Under Chronic Hyperglycemic Conditions.
    Chundru SA; Harajli A; Hali M; Gleason N; Gamage S; Kowluru A
    Cell Physiol Biochem; 2021 Apr; 55(2):180-192. PubMed ID: 33851799
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isoprenylcysteine carboxyl methyltransferase facilitates glucose-induced Rac1 activation, ROS generation and insulin secretion in INS 832/13 β-cells.
    Jayaram B; Syed I; Singh A; Subasinghe W; Kyathanahalli CN; Kowluru A
    Islets; 2011; 3(2):48-57. PubMed ID: 21346419
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Glucotoxicity promotes aberrant activation and mislocalization of Ras-related C3 botulinum toxin substrate 1 [Rac1] and metabolic dysfunction in pancreatic islet β-cells: reversal of such metabolic defects by metformin.
    Baidwan S; Chekuri A; Hynds DL; Kowluru A
    Apoptosis; 2017 Nov; 22(11):1380-1393. PubMed ID: 28828705
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biologically active lipids promote trafficking and membrane association of Rac1 in insulin-secreting INS 832/13 cells.
    McDonald P; Veluthakal R; Kaur H; Kowluru A
    Am J Physiol Cell Physiol; 2007 Mar; 292(3):C1216-20. PubMed ID: 17035298
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of G-proteins in islet function in health and diabetes.
    Kowluru A
    Diabetes Obes Metab; 2017 Sep; 19 Suppl 1(Suppl 1):63-75. PubMed ID: 28880478
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.