464 related articles for article (PubMed ID: 25727255)
21. Improving the efficacy-safety balance of polypharmacology in multi-target drug discovery.
Ravikumar B; Aittokallio T
Expert Opin Drug Discov; 2018 Feb; 13(2):179-192. PubMed ID: 29233023
[TBL] [Abstract][Full Text] [Related]
22. Chemical genetics-based target identification in drug discovery.
Cong F; Cheung AK; Huang SM
Annu Rev Pharmacol Toxicol; 2012; 52():57-78. PubMed ID: 21819237
[TBL] [Abstract][Full Text] [Related]
23. Accessing external innovation in drug discovery and development.
Tufféry P
Expert Opin Drug Discov; 2015 Jun; 10(6):579-89. PubMed ID: 25910932
[TBL] [Abstract][Full Text] [Related]
24. Computational mapping tools for drug discovery.
Ivanenkov YA; Savchuk NP; Ekins S; Balakin KV
Drug Discov Today; 2009 Aug; 14(15-16):767-75. PubMed ID: 19520185
[TBL] [Abstract][Full Text] [Related]
25. Identifying and characterizing promiscuous targets: implications for virtual screening.
Pérez-Nueno VI; Ritchie DW
Expert Opin Drug Discov; 2012 Jan; 7(1):1-17. PubMed ID: 22468890
[TBL] [Abstract][Full Text] [Related]
26. SABRE: ligand/structure-based virtual screening approach using consensus molecular-shape pattern recognition.
Wei NN; Hamza A
J Chem Inf Model; 2014 Jan; 54(1):338-46. PubMed ID: 24328054
[TBL] [Abstract][Full Text] [Related]
27. Structure-based virtual screening for drug discovery: a problem-centric review.
Cheng T; Li Q; Zhou Z; Wang Y; Bryant SH
AAPS J; 2012 Mar; 14(1):133-41. PubMed ID: 22281989
[TBL] [Abstract][Full Text] [Related]
28. Computational approaches for innovative antiepileptic drug discovery.
Talevi A
Expert Opin Drug Discov; 2016 Oct; 11(10):1001-16. PubMed ID: 27454246
[TBL] [Abstract][Full Text] [Related]
29. Using label-free screening technology to improve efficiency in drug discovery.
Halai R; Cooper MA
Expert Opin Drug Discov; 2012 Feb; 7(2):123-31. PubMed ID: 22468914
[TBL] [Abstract][Full Text] [Related]
30. Tools, techniques, organisation and culture of the CADD group at Sygnature Discovery.
St-Gallay SA; Sambrook-Smith CP
J Comput Aided Mol Des; 2017 Mar; 31(3):305-308. PubMed ID: 27798721
[TBL] [Abstract][Full Text] [Related]
31. Biophysical and computational fragment-based approaches to targeting protein-protein interactions: applications in structure-guided drug discovery.
Winter A; Higueruelo AP; Marsh M; Sigurdardottir A; Pitt WR; Blundell TL
Q Rev Biophys; 2012 Nov; 45(4):383-426. PubMed ID: 22971516
[TBL] [Abstract][Full Text] [Related]
32. Novel computational approaches to polypharmacology as a means to define responses to individual drugs.
Xie L; Xie L; Kinnings SL; Bourne PE
Annu Rev Pharmacol Toxicol; 2012; 52():361-79. PubMed ID: 22017683
[TBL] [Abstract][Full Text] [Related]
33. Target identification of small molecules based on chemical biology approaches.
Futamura Y; Muroi M; Osada H
Mol Biosyst; 2013 May; 9(5):897-914. PubMed ID: 23354001
[TBL] [Abstract][Full Text] [Related]
34. The application of Chinese medicine to novel drug discovery.
Sucher NJ
Expert Opin Drug Discov; 2013 Jan; 8(1):21-34. PubMed ID: 23170842
[TBL] [Abstract][Full Text] [Related]
35. Neoclassic drug discovery: the case for lead generation using phenotypic and functional approaches.
Lee JA; Berg EL
J Biomol Screen; 2013 Dec; 18(10):1143-55. PubMed ID: 24080259
[TBL] [Abstract][Full Text] [Related]
36. The application of WaterMap-guided structure-based virtual screening in novel drug discovery.
Kaczor AA; Zięba A; Matosiuk D
Expert Opin Drug Discov; 2024; 19(1):73-83. PubMed ID: 37807912
[TBL] [Abstract][Full Text] [Related]
37. Label-free drug discovery.
Fang Y
Front Pharmacol; 2014; 5():52. PubMed ID: 24723889
[TBL] [Abstract][Full Text] [Related]
38. In silico tools used for compound selection during target-based drug discovery and development.
Caldwell GW
Expert Opin Drug Discov; 2015; 10(8):901-23. PubMed ID: 25952011
[TBL] [Abstract][Full Text] [Related]
39. Integrating medicinal chemistry, organic/combinatorial chemistry, and computational chemistry for the discovery of selective estrogen receptor modulators with Forecaster, a novel platform for drug discovery.
Therrien E; Englebienne P; Arrowsmith AG; Mendoza-Sanchez R; Corbeil CR; Weill N; Campagna-Slater V; Moitessier N
J Chem Inf Model; 2012 Jan; 52(1):210-24. PubMed ID: 22133077
[TBL] [Abstract][Full Text] [Related]
40. Predictive in silico off-target profiling in drug discovery.
Schmidt F; Matter H; Hessler G; Czich A
Future Med Chem; 2014 Mar; 6(3):295-317. PubMed ID: 24575966
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
