210 related articles for article (PubMed ID: 25728928)
1. Structure of the ribosomal oxygenase OGFOD1 provides insights into the regio- and stereoselectivity of prolyl hydroxylases.
Horita S; Scotti JS; Thinnes C; Mottaghi-Taromsari YS; Thalhammer A; Ge W; Aik W; Loenarz C; Schofield CJ; McDonough MA
Structure; 2015 Apr; 23(4):639-52. PubMed ID: 25728928
[TBL] [Abstract][Full Text] [Related]
2. OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation.
Singleton RS; Liu-Yi P; Formenti F; Ge W; Sekirnik R; Fischer R; Adam J; Pollard PJ; Wolf A; Thalhammer A; Loenarz C; Flashman E; Yamamoto A; Coleman ML; Kessler BM; Wappner P; Schofield CJ; Ratcliffe PJ; Cockman ME
Proc Natl Acad Sci U S A; 2014 Mar; 111(11):4031-6. PubMed ID: 24550447
[TBL] [Abstract][Full Text] [Related]
3. Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding.
Thinnes CC; Lohans CT; Abboud MI; Yeh TL; Tumber A; Nowak RP; Attwood M; Cockman ME; Oppermann U; Loenarz C; Schofield CJ
Chemistry; 2019 Feb; 25(8):2019-2024. PubMed ID: 30427558
[TBL] [Abstract][Full Text] [Related]
4. Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation.
Scotti JS; Leung IK; Ge W; Bentley MA; Paps J; Kramer HB; Lee J; Aik W; Choi H; Paulsen SM; Bowman LA; Loik ND; Horita S; Ho CH; Kershaw NJ; Tang CM; Claridge TD; Preston GM; McDonough MA; Schofield CJ
Proc Natl Acad Sci U S A; 2014 Sep; 111(37):13331-6. PubMed ID: 25197067
[TBL] [Abstract][Full Text] [Related]
5. Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy.
Loenarz C; Sekirnik R; Thalhammer A; Ge W; Spivakovsky E; Mackeen MM; McDonough MA; Cockman ME; Kessler BM; Ratcliffe PJ; Wolf A; Schofield CJ
Proc Natl Acad Sci U S A; 2014 Mar; 111(11):4019-24. PubMed ID: 24550462
[TBL] [Abstract][Full Text] [Related]
6. Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth.
Katz MJ; Acevedo JM; Loenarz C; Galagovsky D; Liu-Yi P; Pérez-Pepe M; Thalhammer A; Sekirnik R; Ge W; Melani M; Thomas MG; Simonetta S; Boccaccio GL; Schofield CJ; Cockman ME; Ratcliffe PJ; Wappner P
Proc Natl Acad Sci U S A; 2014 Mar; 111(11):4025-30. PubMed ID: 24550463
[TBL] [Abstract][Full Text] [Related]
7. The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation and modulates translation and splicing.
Stoehr A; Kennedy L; Yang Y; Patel S; Lin Y; Linask KL; Fergusson M; Zhu J; Gucek M; Zou J; Murphy E
JCI Insight; 2019 May; 5(13):. PubMed ID: 31112528
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of a viral prolyl hydroxylase.
Langley GW; Abboud MI; Lohans CT; Schofield CJ
Bioorg Med Chem; 2019 Jun; 27(12):2405-2412. PubMed ID: 30737136
[TBL] [Abstract][Full Text] [Related]
9. Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible factor.
Kiriakidis S; Hoer SS; Burrows N; Biddlecome G; Khan MN; Thinnes CC; Schofield CJ; Rogers N; Botto M; Paleolog E; Maxwell PH
Kidney Int; 2017 Oct; 92(4):900-908. PubMed ID: 28506759
[TBL] [Abstract][Full Text] [Related]
10. Recent Advances in Developing Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylases and Their Therapeutic Implications.
Kim SY; Yang EG
Molecules; 2015 Nov; 20(11):20551-68. PubMed ID: 26610437
[TBL] [Abstract][Full Text] [Related]
11. Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat.
Figg WD; McDonough MA; Chowdhury R; Nakashima Y; Zhang Z; Holt-Martyn JP; Krajnc A; Schofield CJ
ChemMedChem; 2021 Jul; 16(13):2082-2088. PubMed ID: 33792169
[TBL] [Abstract][Full Text] [Related]
12. Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complex.
Kim HS; Kim HL; Kim KH; Kim DJ; Lee SJ; Yoon JY; Yoon HJ; Lee HY; Park SB; Kim SJ; Lee JY; Suh SW
Nucleic Acids Res; 2010 Apr; 38(6):2099-110. PubMed ID: 20040577
[TBL] [Abstract][Full Text] [Related]
13. Differences between collagen hydroxylases and 2-oxoglutarate dehydrogenase in their inhibition by structural analogues of 2-oxoglutarate.
Majamaa K; Turpeenniemi-Hujanen TM; Latipää P; Günzler V; Hanauske-Abel HM; Hassinen IE; Kivirikko KI
Biochem J; 1985 Jul; 229(1):127-33. PubMed ID: 2994628
[TBL] [Abstract][Full Text] [Related]
14. Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Chowdhury R; Sekirnik R; Brissett NC; Krojer T; Ho CH; Ng SS; Clifton IJ; Ge W; Kershaw NJ; Fox GC; Muniz JRC; Vollmar M; Phillips C; Pilka ES; Kavanagh KL; von Delft F; Oppermann U; McDonough MA; Doherty AJ; Schofield CJ
Nature; 2014 Jun; 510(7505):422-426. PubMed ID: 24814345
[TBL] [Abstract][Full Text] [Related]
15. 5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.
Hopkinson RJ; Tumber A; Yapp C; Chowdhury R; Aik W; Che KH; Li XS; Kristensen JBL; King ONF; Chan MC; Yeoh KK; Choi H; Walport LJ; Thinnes CC; Bush JT; Lejeune C; Rydzik AM; Rose NR; Bagg EA; McDonough MA; Krojer T; Yue WW; Ng SS; Olsen L; Brennan PE; Oppermann U; Muller-Knapp S; Klose RJ; Ratcliffe PJ; Schofield CJ; Kawamura A
Chem Sci; 2013 Aug; 4(8):3110-3117. PubMed ID: 26682036
[TBL] [Abstract][Full Text] [Related]
16. Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
Chowdhury R; McDonough MA; Mecinović J; Loenarz C; Flashman E; Hewitson KS; Domene C; Schofield CJ
Structure; 2009 Jul; 17(7):981-9. PubMed ID: 19604478
[TBL] [Abstract][Full Text] [Related]
17. Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases.
Brewitz L; Nakashima Y; Tumber A; Salah E; Schofield CJ
J Fluor Chem; 2021 Jul; 247():109804. PubMed ID: 34219804
[TBL] [Abstract][Full Text] [Related]
18. Hypoxia-inducible factor prolyl 4-hydroxylase inhibition in cardiometabolic diseases.
Koivunen P; Serpi R; Dimova EY
Pharmacol Res; 2016 Dec; 114():265-273. PubMed ID: 27832958
[TBL] [Abstract][Full Text] [Related]
19. Collagen Peptides as a Hypoxia-Inducible Factor-2α-Stabilizing Prolyl Hydroxylase Inhibitor to Stimulate Intestinal Iron Absorption by Upregulating Iron Transport Proteins.
Zhu S; Wu L; Zhang M; Li S; Xing W; Zhao Z; Guo H; Ma L; Wu H
J Agric Food Chem; 2022 Dec; 70(48):15095-15103. PubMed ID: 36475394
[TBL] [Abstract][Full Text] [Related]
20. Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Yeh TL; Leissing TM; Abboud MI; Thinnes CC; Atasoylu O; Holt-Martyn JP; Zhang D; Tumber A; Lippl K; Lohans CT; Leung IKH; Morcrette H; Clifton IJ; Claridge TDW; Kawamura A; Flashman E; Lu X; Ratcliffe PJ; Chowdhury R; Pugh CW; Schofield CJ
Chem Sci; 2017 Nov; 8(11):7651-7668. PubMed ID: 29435217
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
