210 related articles for article (PubMed ID: 25728928)
21. Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Yeh TL; Leissing TM; Abboud MI; Thinnes CC; Atasoylu O; Holt-Martyn JP; Zhang D; Tumber A; Lippl K; Lohans CT; Leung IKH; Morcrette H; Clifton IJ; Claridge TDW; Kawamura A; Flashman E; Lu X; Ratcliffe PJ; Chowdhury R; Pugh CW; Schofield CJ
Chem Sci; 2017 Nov; 8(11):7651-7668. PubMed ID: 29435217
[TBL] [Abstract][Full Text] [Related]
22. Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
Flashman E; Davies SL; Yeoh KK; Schofield CJ
Biochem J; 2010 Mar; 427(1):135-42. PubMed ID: 20055761
[TBL] [Abstract][Full Text] [Related]
23. NADPH oxidase-mitochondria axis-derived ROS mediate arsenite-induced HIF-1α stabilization by inhibiting prolyl hydroxylases activity.
Li YN; Xi MM; Guo Y; Hai CX; Yang WL; Qin XJ
Toxicol Lett; 2014 Jan; 224(2):165-74. PubMed ID: 24188932
[TBL] [Abstract][Full Text] [Related]
24. OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling.
Saito K; Adachi N; Koyama H; Matsushita M
FEBS Lett; 2010 Aug; 584(15):3340-7. PubMed ID: 20579638
[TBL] [Abstract][Full Text] [Related]
25. Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal
Lippl K; Boleininger A; McDonough MA; Abboud MI; Tarhonskaya H; Chowdhury R; Loenarz C; Schofield CJ
Hypoxia (Auckl); 2018; 6():57-71. PubMed ID: 30519597
[TBL] [Abstract][Full Text] [Related]
26. Protein hydroxylation: prolyl 4-hydroxylase, an enzyme with four cosubstrates and a multifunctional subunit.
Kivirikko KI; Myllylä R; Pihlajaniemi T
FASEB J; 1989 Mar; 3(5):1609-17. PubMed ID: 2537773
[TBL] [Abstract][Full Text] [Related]
27. Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes.
Stoehr A; Yang Y; Patel S; Evangelista AM; Aponte A; Wang G; Liu P; Boylston J; Kloner PH; Lin Y; Gucek M; Zhu J; Murphy E
Cardiovasc Res; 2016 Jun; 110(3):346-58. PubMed ID: 27095734
[TBL] [Abstract][Full Text] [Related]
28. Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation.
Masson N; Willam C; Maxwell PH; Pugh CW; Ratcliffe PJ
EMBO J; 2001 Sep; 20(18):5197-206. PubMed ID: 11566883
[TBL] [Abstract][Full Text] [Related]
29. Endogenous 2-oxoglutarate levels impact potencies of competitive HIF prolyl hydroxylase inhibitors.
Thirstrup K; Christensen S; Møller HA; Ritzén A; Bergström AL; Sager TN; Jensen HS
Pharmacol Res; 2011 Sep; 64(3):268-73. PubMed ID: 21504793
[TBL] [Abstract][Full Text] [Related]
30. Prolyl dihydroxylation of unassembled uS12/Rps23 regulates fungal hypoxic adaptation.
Clasen SJ; Shao W; Gu H; Espenshade PJ
Elife; 2017 Oct; 6():. PubMed ID: 29083304
[TBL] [Abstract][Full Text] [Related]
31. HIF-prolyl hydroxylases and cardiovascular diseases.
Sen Banerjee S; Thirunavukkarasu M; Tipu Rishi M; Sanchez JA; Maulik N; Maulik G
Toxicol Mech Methods; 2012 Jun; 22(5):347-58. PubMed ID: 22424133
[TBL] [Abstract][Full Text] [Related]
32. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
Berra E; Benizri E; Ginouvès A; Volmat V; Roux D; Pouysségur J
EMBO J; 2003 Aug; 22(16):4082-90. PubMed ID: 12912907
[TBL] [Abstract][Full Text] [Related]
33. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
34. Inhibition of JMJD6 by 2-Oxoglutarate Mimics.
Islam MS; Thinnes CC; Holt-Martyn JP; Chowdhury R; McDonough MA; Schofield CJ
ChemMedChem; 2022 Jan; 17(1):e202100398. PubMed ID: 34581506
[TBL] [Abstract][Full Text] [Related]
35. The Isoquinolone Derived Prolyl Hydroxylase Inhibitor ICA Is a Potent Substrate of the Organic Anion Transporters 1 and 3.
Schulz K; Hagos Y; Burckhardt G; Schley G; Burzlaff N; Willam C; Burckhardt BC
Nephron; 2015; 131(4):285-9. PubMed ID: 26640952
[TBL] [Abstract][Full Text] [Related]
36. 1.9 A resolution crystal structure of the Saccharomyces cerevisiae Ran-binding protein Mog1p.
Stewart M; Baker RP
J Mol Biol; 2000 May; 299(1):213-23. PubMed ID: 10860733
[TBL] [Abstract][Full Text] [Related]
37. Application of in-vitro screening methods on hypoxia inducible factor prolyl hydroxylase inhibitors.
Wu Y; Jiang Z; You Q; Zhang X
Bioorg Med Chem; 2017 Aug; 25(15):3891-3899. PubMed ID: 28625716
[TBL] [Abstract][Full Text] [Related]
38. Molecular characterization and mRNA expression of HIF-prolyl hydroxylase-2 (phd2) in hypoxia-sensing pathways from Megalobrama amblycephala.
Wang H; Huang C; Chen N; Zhu K; Chen B; Wang W; Wang H
Comp Biochem Physiol B Biochem Mol Biol; 2015 Aug; 186():28-35. PubMed ID: 25868626
[TBL] [Abstract][Full Text] [Related]
39. Leu-574 of human HIF-1alpha is a molecular determinant of prolyl hydroxylation.
Kageyama Y; Koshiji M; To KK; Tian YM; Ratcliffe PJ; Huang LE
FASEB J; 2004 Jun; 18(9):1028-30. PubMed ID: 15084514
[TBL] [Abstract][Full Text] [Related]
40. Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing.
Mole DR; Maxwell PH; Pugh CW; Ratcliffe PJ
IUBMB Life; 2001 Jul; 52(1-2):43-7. PubMed ID: 11795592
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
