These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 25729577)

  • 1. Jadomycin breast cancer cytotoxicity is mediated by a copper-dependent, reactive oxygen species-inducing mechanism.
    Hall SR; Blundon HL; Ladda MA; Robertson AW; Martinez-Farina CF; Jakeman DL; Goralski KB
    Pharmacol Res Perspect; 2015 Mar; 3(2):e00110. PubMed ID: 25729577
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Jadomycins Inhibit Type II Topoisomerases and Promote DNA Damage and Apoptosis in Multidrug-Resistant Triple-Negative Breast Cancer Cells.
    Hall SR; Toulany J; Bennett LG; Martinez-Farina CF; Robertson AW; Jakeman DL; Goralski KB
    J Pharmacol Exp Ther; 2017 Nov; 363(2):196-210. PubMed ID: 28904004
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Isolation of a jadomycin incorporating L-ornithine, analysis of antimicrobial activity and jadomycin reactive oxygen species (ROS) generation in MDA-MB-231 breast cancer cells.
    Forget SM; Robertson AW; Hall SR; MacLeod JM; Overy DP; Kerr RG; Goralski KB; Jakeman DL
    J Antibiot (Tokyo); 2018 Aug; 71(8):722-730. PubMed ID: 29700425
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The variable chemotherapeutic response of Malabaricone-A in leukemic and solid tumor cell lines depends on the degree of redox imbalance.
    Manna A; De Sarkar S; De S; Bauri AK; Chattopadhyay S; Chatterjee M
    Phytomedicine; 2015 Jul; 22(7-8):713-23. PubMed ID: 26141757
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Copper-mediated nuclease activity of jadomycin B.
    Monro SM; Cottreau KM; Spencer C; Wentzell JR; Graham CL; Borissow CN; Jakeman DL; McFarland SA
    Bioorg Med Chem; 2011 Jun; 19(11):3357-60. PubMed ID: 21565515
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Jadomycins: A potential chemotherapy for multi-drug resistant metastatic breast cancer.
    Bonitto EP; McKeown BT; Goralski KB
    Pharmacol Res Perspect; 2021 Dec; 9(6):e00886. PubMed ID: 34708587
    [TBL] [Abstract][Full Text] [Related]  

  • 7.
    Forget SM; McVey J; Vining LC; Jakeman DL
    Front Microbiol; 2017; 8():432. PubMed ID: 28377749
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reactive Oxygen Species Mediate TNF-x237A; Cytotoxic Effects in the Multidrug-Resistant Breast Cancer Cell Line MCF-7/MX.
    Ghandadi M; Behravan J; Abnous K; Mosaffa F
    Oncol Res Treat; 2016; 39(1-2):54-9. PubMed ID: 26890889
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biosynthesis, synthetic studies, and biological activities of the jadomycin alkaloids and related analogues.
    de Koning CB; Ngwira KJ; Rousseau AL
    Alkaloids Chem Biol; 2020; 84():125-199. PubMed ID: 32416952
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Jadomycins derived from the assimilation and incorporation of norvaline and norleucine.
    Dupuis SN; Veinot T; Monro SM; Douglas SE; Syvitski RT; Goralski KB; McFarland SA; Jakeman DL
    J Nat Prod; 2011 Nov; 74(11):2420-4. PubMed ID: 22050382
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The thioredoxin antioxidant system.
    Lu J; Holmgren A
    Free Radic Biol Med; 2014 Jan; 66():75-87. PubMed ID: 23899494
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and discovery of novel quinazolinedione-based redox modulators as therapies for pancreatic cancer.
    Pathania D; Sechi M; Palomba M; Sanna V; Berrettini F; Sias A; Taheri L; Neamati N
    Biochim Biophys Acta; 2014 Jan; 1840(1):332-43. PubMed ID: 23954204
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytotoxic effects of N'-formyl-2-(5-nitrothiophen-2-yl) benzothiazole-6-carbohydrazide in human breast tumor cells by induction of oxidative stress.
    Rodrigues JR; Charris J; Camacho J; Barazarte A; Gamboa N; Antunes F
    Anticancer Res; 2012 Jul; 32(7):2721-6. PubMed ID: 22753731
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Copper chelation by D-penicillamine generates reactive oxygen species that are cytotoxic to human leukemia and breast cancer cells.
    Gupte A; Mumper RJ
    Free Radic Biol Med; 2007 Nov; 43(9):1271-8. PubMed ID: 17893040
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of intracellular reactive oxygen species level in chondrocytes by IGF-1, FGF, and TGF-beta1.
    Jallali N; Ridha H; Thrasivoulou C; Butler P; Cowen T
    Connect Tissue Res; 2007; 48(3):149-58. PubMed ID: 17522998
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of Cu/Zn-superoxide dismutase in xenobiotic activation. II. Biological effects resulting from the Cu/Zn-superoxide dismutase-accelerated oxidation of the benzene metabolite 1,4-hydroquinone.
    Li Y; Kuppusamy P; Zweir JL; Trush MA
    Mol Pharmacol; 1996 Mar; 49(3):412-21. PubMed ID: 8643080
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrial DNA depletion promotes impaired oxidative status and adaptive resistance to apoptosis in T47D breast cancer cells.
    Yu M; Shi Y; Wei X; Yang Y; Zang F; Niu R
    Eur J Cancer Prev; 2009 Nov; 18(6):445-57. PubMed ID: 19609211
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chronic Effects of Ethanol and/or Darunavir/Ritonavir on U937 Monocytic Cells: Regulation of Cytochrome P450 and Antioxidant Enzymes, Oxidative Stress, and Cytotoxicity.
    Rao PS; Kumar S
    Alcohol Clin Exp Res; 2016 Jan; 40(1):73-82. PubMed ID: 26727525
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of the cytotoxic activity of new jadomycin derivatives reveals the potential to improve its selectivity against tumor cells.
    Fan K; Zhang X; Liu H; Han H; Luo Y; Wang Q; Geng M; Yang K
    J Antibiot (Tokyo); 2012 Sep; 65(9):449-52. PubMed ID: 22714025
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pilot study of jadomycin B pharmacokinetics and anti-tumoral effects in zebrafish larvae and mouse breast cancer xenograft models.
    McKeown BT; Relja NJ; Hall SR; Gebremeskel S; MacLeod JM; Veinotte CJ; Bennett LG; Ohlund LB; Sleno L; Jakeman DL; Berman JN; Johnston B; Goralski KB
    Can J Physiol Pharmacol; 2022 Nov; 100(11):1065-1076. PubMed ID: 35985040
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.