BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

328 related articles for article (PubMed ID: 25729885)

  • 1. Small molecule schweinfurthins selectively inhibit cancer cell proliferation and mTOR/AKT signaling by interfering with trans-Golgi-network trafficking.
    Bao X; Zheng W; Hata Sugi N; Agarwala KL; Xu Q; Wang Z; Tendyke K; Lee W; Parent L; Li W; Cheng H; Shen Y; Taylor N; Dezso Z; Du H; Kotake Y; Zhao N; Wang J; Postema M; Woodall-Jappe M; Takase Y; Uenaka T; Kingston DG; Nomoto K
    Cancer Biol Ther; 2015; 16(4):589-601. PubMed ID: 25729885
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling.
    He X; Wang Y; Zhu J; Orloff M; Eng C
    Cancer Lett; 2011 Feb; 301(2):168-76. PubMed ID: 21168265
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BMI1 promotes cardiac fibrosis in ischemia-induced heart failure via the PTEN-PI3K/Akt-mTOR signaling pathway.
    Yang W; Wu Z; Yang K; Han Y; Chen Y; Zhao W; Huang F; Jin Y; Jin W
    Am J Physiol Heart Circ Physiol; 2019 Jan; 316(1):H61-H69. PubMed ID: 30359076
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Expression and Prognostic Impact of the PI3K/AKT/mTOR Signaling Pathway in Advanced Esophageal Squamous Cell Carcinoma.
    Wu N; Du Z; Zhu Y; Song Y; Pang L; Chen Z
    Technol Cancer Res Treat; 2018 Jan; 17():1533033818758772. PubMed ID: 29463194
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways.
    Leu WJ; Swain ShP; Chan SH; Hsu JL; Liu SP; Chan ML; Yu CC; Hsu LC; Chou YL; Chang WL; Hou DR; Guh JH
    Oncotarget; 2016 Nov; 7(47):76995-77009. PubMed ID: 27769069
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Marsdenia tenacissimae extraction (MTE) inhibits the proliferation and induces the apoptosis of human acute T cell leukemia cells through inactivating PI3K/AKT/mTOR signaling pathway via PTEN enhancement.
    Wang Y; Chen B; Wang Z; Zhang W; Hao K; Chen Y; Li K; Wang T; Xie Y; Huang Z; Tong X
    Oncotarget; 2016 Dec; 7(50):82851-82863. PubMed ID: 27756877
    [TBL] [Abstract][Full Text] [Related]  

  • 7. S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton.
    Zhang C; Yang N; Yang CH; Ding HS; Luo C; Zhang Y; Wu MJ; Zhang XW; Shen X; Jiang HL; Meng LH; Ding J
    PLoS One; 2009; 4(3):e4881. PubMed ID: 19293927
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M; Kasprzycka M; Liu X; El-Salem M; Halasa K; Raghunath PN; Bucki R; Wlodarski P; Wasik MA
    Oncogene; 2007 Aug; 26(38):5606-14. PubMed ID: 17353907
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
    Vega F; Medeiros LJ; Leventaki V; Atwell C; Cho-Vega JH; Tian L; Claret FX; Rassidakis GZ
    Cancer Res; 2006 Jul; 66(13):6589-97. PubMed ID: 16818631
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thymosin alpha 1 suppresses proliferation and induces apoptosis in breast cancer cells through PTEN-mediated inhibition of PI3K/Akt/mTOR signaling pathway.
    Guo Y; Chang H; Li J; Xu XY; Shen L; Yu ZB; Liu WC
    Apoptosis; 2015 Aug; 20(8):1109-21. PubMed ID: 26002438
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ursolic acid attenuates diabetic mesangial cell injury through the up-regulation of autophagy via miRNA-21/PTEN/Akt/mTOR suppression.
    Lu X; Fan Q; Xu L; Li L; Yue Y; Xu Y; Su Y; Zhang D; Wang L
    PLoS One; 2015; 10(2):e0117400. PubMed ID: 25689721
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Brassinin induces apoptosis in PC-3 human prostate cancer cells through the suppression of PI3K/Akt/mTOR/S6K1 signaling cascades.
    Kim SM; Park JH; Kim KD; Nam D; Shim BS; Kim SH; Ahn KS; Choi SH; Ahn KS
    Phytother Res; 2014 Mar; 28(3):423-31. PubMed ID: 23686889
    [TBL] [Abstract][Full Text] [Related]  

  • 13. S6K Promotes Dopaminergic Neuronal Differentiation Through PI3K/Akt/mTOR-Dependent Signaling Pathways in Human Neural Stem Cells.
    Lee JE; Lim MS; Park JH; Park CH; Koh HC
    Mol Neurobiol; 2016 Aug; 53(6):3771-3782. PubMed ID: 26143260
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Schweinfurthins: Lipid Modulators with Promising Anticancer Activity.
    Koubek EJ; Weissenrieder JS; Neighbors JD; Hohl RJ
    Lipids; 2018 Aug; 53(8):767-784. PubMed ID: 30334267
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network.
    Chen S; Gu C; Xu C; Zhang J; Xu Y; Ren Q; Guo M; Huang S; Chen L
    J Neurochem; 2014 Jan; 128(2):256-266. PubMed ID: 24111524
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway.
    White ES; Sagana RL; Booth AJ; Yan M; Cornett AM; Bloomheart CA; Tsui JL; Wilke CA; Moore BB; Ritzenthaler JD; Roman J; Muro AF
    Exp Cell Res; 2010 Oct; 316(16):2644-53. PubMed ID: 20615404
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Negative regulation of PI3K/AKT/mTOR axis regulates fibroblast proliferation, apoptosis and autophagy play a vital role in triptolide-induced epidural fibrosis reduction.
    Dai J; Sun Y; Chen D; Zhang Y; Yan L; Li X; Wang J
    Eur J Pharmacol; 2019 Dec; 864():172724. PubMed ID: 31600493
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of the PI3K/Akt/mTOR signaling pathway in diffuse large B-cell lymphoma: current knowledge and clinical significance.
    Majchrzak A; Witkowska M; Smolewski P
    Molecules; 2014 Sep; 19(9):14304-15. PubMed ID: 25215588
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PI3K/AKT Pathway and Its Mediators in Thyroid Carcinomas.
    Nozhat Z; Hedayati M
    Mol Diagn Ther; 2016 Feb; 20(1):13-26. PubMed ID: 26597586
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphatidylinositol 3-kinase (PI3K) signalling regulates insulin-like-growth factor binding protein-2 (IGFBP-2) production in human adipocytes.
    Wilhelm F; Kässner F; Schmid G; Kratzsch J; Laner A; Wabitsch M; Körner A; Kiess W; Garten A
    Growth Horm IGF Res; 2015 Jun; 25(3):115-20. PubMed ID: 25900365
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.