These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 25730874)

  • 1. Mutant IDH is sufficient to initiate enchondromatosis in mice.
    Hirata M; Sasaki M; Cairns RA; Inoue S; Puviindran V; Li WY; Snow BE; Jones LD; Wei Q; Sato S; Tang YJ; Nadesan P; Rockel J; Whetstone H; Poon R; Weng A; Gross S; Straley K; Gliser C; Xu Y; Wunder J; Mak TW; Alman BA
    Proc Natl Acad Sci U S A; 2015 Mar; 112(9):2829-34. PubMed ID: 25730874
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells.
    Li L; Paz AC; Wilky BA; Johnson B; Galoian K; Rosenberg A; Hu G; Tinoco G; Bodamer O; Trent JC
    PLoS One; 2015; 10(9):e0133813. PubMed ID: 26368816
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IDH1 immunohistochemistry reactivity and mosaic IDH1 or IDH2 somatic mutations in pediatric sporadic enchondroma and enchondromatosis.
    Saiji E; Pause FG; Lascombes P; Cerato Biderbost C; Marq NL; Berczy M; Merlini L; Rougemont AL
    Virchows Arch; 2019 Nov; 475(5):625-636. PubMed ID: 31240473
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes.
    Jin Y; Elalaf H; Watanabe M; Tamaki S; Hineno S; Matsunaga K; Woltjen K; Kobayashi Y; Nagata S; Ikeya M; Kato T; Okamoto T; Matsuda S; Toguchida J
    PLoS One; 2015; 10(7):e0131998. PubMed ID: 26161668
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization.
    Ward PS; Lu C; Cross JR; Abdel-Wahab O; Levine RL; Schwartz GK; Thompson CB
    J Biol Chem; 2013 Feb; 288(6):3804-15. PubMed ID: 23264629
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours.
    Amary MF; Bacsi K; Maggiani F; Damato S; Halai D; Berisha F; Pollock R; O'Donnell P; Grigoriadis A; Diss T; Eskandarpour M; Presneau N; Hogendoorn PC; Futreal A; Tirabosco R; Flanagan AM
    J Pathol; 2011 Jul; 224(3):334-43. PubMed ID: 21598255
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A mutant PTH/PTHrP type I receptor in enchondromatosis.
    Hopyan S; Gokgoz N; Poon R; Gensure RC; Yu C; Cole WG; Bell RS; Jüppner H; Andrulis IL; Wunder JS; Alman BA
    Nat Genet; 2002 Mar; 30(3):306-10. PubMed ID: 11850620
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isocitrate dehydrogenase (IDH) mutations promote a reversible ZEB1/microRNA (miR)-200-dependent epithelial-mesenchymal transition (EMT).
    Grassian AR; Lin F; Barrett R; Liu Y; Jiang W; Korpal M; Astley H; Gitterman D; Henley T; Howes R; Levell J; Korn JM; Pagliarini R
    J Biol Chem; 2012 Dec; 287(50):42180-94. PubMed ID: 23038259
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitor potency varies widely among tumor-relevant human isocitrate dehydrogenase 1 mutants.
    Avellaneda Matteo D; Wells GA; Luna LA; Grunseth AJ; Zagnitko O; Scott DA; Hoang A; Luthra A; Swairjo MA; Schiffer JM; Sohl CD
    Biochem J; 2018 Oct; 475(20):3221-3238. PubMed ID: 30249606
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct Roles of Glutamine Metabolism in Benign and Malignant Cartilage Tumors With IDH Mutations.
    Zhang H; Puviindran V; Nadesan P; Ding X; Shen L; Tang YJ; Tsushima H; Yahara Y; Ban GI; Zhang GF; Karner CM; Alman BA
    J Bone Miner Res; 2022 May; 37(5):983-996. PubMed ID: 35220602
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with isocitrate dehydrogenase-mutated glioma.
    Lombardi G; Corona G; Bellu L; Della Puppa A; Pambuku A; Fiduccia P; Bertorelle R; Gardiman MP; D'Avella D; Toffoli G; Zagonel V
    Oncologist; 2015 May; 20(5):562-7. PubMed ID: 25862748
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation.
    Pathmanapan S; Poon R; De Renshaw TB; Nadesan P; Nakagawa M; Seesankar GA; Ho Loe AK; Zhang HH; Guinovart JJ; Duran J; Newgard CB; Wunder JS; Alman BA
    Cell Rep; 2023 Jun; 42(6):112578. PubMed ID: 37267108
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome.
    Pansuriya TC; van Eijk R; d'Adamo P; van Ruler MA; Kuijjer ML; Oosting J; Cleton-Jansen AM; van Oosterwijk JG; Verbeke SL; Meijer D; van Wezel T; Nord KH; Sangiorgi L; Toker B; Liegl-Atzwanger B; San-Julian M; Sciot R; Limaye N; Kindblom LG; Daugaard S; Godfraind C; Boon LM; Vikkula M; Kurek KC; Szuhai K; French PJ; Bovée JV
    Nat Genet; 2011 Nov; 43(12):1256-61. PubMed ID: 22057234
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Somatic mosaic mutations of IDH1 and NPM1 associated with cup-like acute myeloid leukemia in a patient with Maffucci syndrome.
    Akiyama M; Yamaoka M; Mikami-Terao Y; Ohyama W; Yokoi K; Arakawa Y; Takita J; Suzuki H; Yamada H
    Int J Hematol; 2015 Dec; 102(6):723-8. PubMed ID: 26508204
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Circulating oncometabolite D-2-hydroxyglutarate enantiomer is a surrogate marker of isocitrate dehydrogenase-mutated intrahepatic cholangiocarcinomas.
    Delahousse J; Verlingue L; Broutin S; Legoupil C; Touat M; Doucet L; Ammari S; Lacroix L; Ducreux M; Scoazec JY; Malka D; Paci A; Hollebecque A
    Eur J Cancer; 2018 Feb; 90():83-91. PubMed ID: 29274619
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila.
    Reitman ZJ; Sinenko SA; Spana EP; Yan H
    Blood; 2015 Jan; 125(2):336-45. PubMed ID: 25398939
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Single-cell transcriptomic analyses of mouse idh1 mutant growth plate chondrocytes reveal distinct cell populations responsible for longitudinal growth and enchondroma formation.
    Puviindran V; Shimada E; Huang Z; Ma X; Ban GI; Xiang Y; Zhang H; Ou J; Wei X; Nakagawa M; Martin J; Diao Y; Alman BA
    Res Sq; 2024 Jun; ():. PubMed ID: 38883785
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IDH1 R132C and ERC2 L309I Mutations Contribute to the Development of Maffucci's Syndrome.
    Cheng P; Chen K; Zhang S; Mu KT; Liang S; Zhang Y
    Front Endocrinol (Lausanne); 2021; 12():763349. PubMed ID: 34790172
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Somatic IDH1 mutation in a pituitary adenoma of a patient with Maffucci syndrome.
    Hao S; Hong CS; Feng J; Yang C; Chittiboina P; Zhang J; Zhuang Z
    J Neurosurg; 2016 Jun; 124(6):1562-7. PubMed ID: 26473790
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enchondromatosis and Growth Plate Development.
    Zhang H; Alman BA
    Curr Osteoporos Rep; 2021 Feb; 19(1):40-49. PubMed ID: 33306166
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.