BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 25736993)

  • 1. Design, synthesis and preliminary biological evaluation of C-8 substituted guanine derivatives as small molecular inhibitors of FGFRs.
    Ye F; Chen L; Hu L; Xiao T; Yu S; Chen D; Wang Y; Liang G; Liu Z; Wang S
    Bioorg Med Chem Lett; 2015 Apr; 25(7):1556-60. PubMed ID: 25736993
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1.
    Gryshchenko AA; Tarnavskiy SS; Levchenko KV; Bdzhola VG; Volynets GP; Golub AG; Ruban TP; Vygranenko KV; Lukash LL; Yarmoluk SM
    Bioorg Med Chem; 2016 May; 24(9):2053-9. PubMed ID: 27017541
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and biological evaluation of 3-vinyl-quinoxalin-2(1H)-one derivatives as novel antitumor inhibitors of FGFR1.
    Liu Z; Yu S; Chen D; Shen G; Wang Y; Hou L; Lin D; Zhang J; Ye F
    Drug Des Devel Ther; 2016; 10():1489-500. PubMed ID: 27217720
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and biological evaluation of N-phenylthieno[2,3-d]pyrimidin-4-amines as inhibitors of FGFR1.
    Gryshchenko AA; Bdzhola VG; Balanda AO; Briukhovetska NV; Kotey IM; Golub AG; Ruban TP; Lukash LL; Yarmoluk SM
    Bioorg Med Chem; 2015 May; 23(9):2287-93. PubMed ID: 25817240
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, Synthesis, and Biological Evaluation of C-2 Substituted 3Hthieno[ 2,3-d]pyrimidin-4-one Derivatives as Novel FGFR1 Inhibitors.
    Guo P; Xie Z; Zhang H; Zhang Z; Han C; Cheng D; Lin D; Zhang Y; Wang X; Guo X; Ye F
    Med Chem; 2017; 13(8):753-760. PubMed ID: 28641527
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of novel 1
    Liu J; Wen Y; Gao L; Gao L; He F; Zhou J; Wang J; Dai R; Chen X; Kang D; Hu L
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):72-84. PubMed ID: 31682465
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of novel FGFR inhibitors bearing an indazole scaffold.
    Liu J; Peng X; Dai Y; Zhang W; Ren S; Ai J; Geng M; Li Y
    Org Biomol Chem; 2015 Jul; 13(28):7643-54. PubMed ID: 26080733
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, Synthesis and Biological Evaluation of 6-(2,6-Dichloro-3,5-dimethoxyphenyl)-4-substituted-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors.
    Zhang Z; Zhao D; Dai Y; Cheng M; Geng M; Shen J; Ma Y; Ai J; Xiong B
    Molecules; 2016 Oct; 21(10):. PubMed ID: 27782099
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and biological evaluation of 4-bromo-N-(3,5-dimethoxyphenyl)benzamide derivatives as novel FGFR1 inhibitors for treatment of non-small cell lung cancer.
    Xie Z; Cheng D; Luo L; Shen G; Pan S; Pan Y; Chen B; Wang X; Liu Z; Zhang Y; Ye F
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):905-919. PubMed ID: 29734851
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of purin-2-yl and purin-6-yl-aminoglucitols as C-nucleosidic ATP mimics and biological evaluation as FGFR3 inhibitors.
    Tak-Tak L; Barbault F; Maurel F; Busca P; Le Merrer Y
    Eur J Med Chem; 2011 Apr; 46(4):1254-62. PubMed ID: 21334122
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and docking studies of afatinib analogs bearing cinnamamide moiety as potent EGFR inhibitors.
    Tu Y; OuYang Y; Xu S; Zhu Y; Li G; Sun C; Zheng P; Zhu W
    Bioorg Med Chem; 2016 Apr; 24(7):1495-503. PubMed ID: 26906472
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, anticancer evaluation and molecular docking of new benzothiazole scaffolds targeting FGFR-1.
    Abd El-Meguid EA; Mohi El-Deen EM; Moustafa GO; Awad HM; Nossier ES
    Bioorg Chem; 2022 Feb; 119():105504. PubMed ID: 34836644
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, Synthesis and in Vitro Tumor Cytotoxicity Evaluation of 3,5-Diamino-N-substituted Benzamide Derivatives as Novel GSK-3β Small Molecule Inhibitors.
    Zhou Y; Zhang L; Fu X; Jiang Z; Tong R; Shi J; Li J; Zhong L
    Chem Biodivers; 2019 Sep; 16(9):e1900304. PubMed ID: 31338947
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-Oxo-3, 4-dihydropyrimido[4, 5-d]pyrimidinyl derivatives as new irreversible pan fibroblast growth factor receptor (FGFR) inhibitors.
    Li X; Guise CP; Taghipouran R; Yosaatmadja Y; Ashoorzadeh A; Paik WK; Squire CJ; Jiang S; Luo J; Xu Y; Tu ZC; Lu X; Ren X; Patterson AV; Smaill JB; Ding K
    Eur J Med Chem; 2017 Jul; 135():531-543. PubMed ID: 28521156
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Acenaphtho[1,2-b]pyrrole-based selective fibroblast growth factor receptors 1 (FGFR1) inhibitors: design, synthesis, and biological activity.
    Chen Z; Wang X; Zhu W; Cao X; Tong L; Li H; Xie H; Xu Y; Tan S; Kuang D; Ding J; Qian X
    J Med Chem; 2011 Jun; 54(11):3732-45. PubMed ID: 21517068
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of N-(2-phenyl-1H-benzo[d]imidazol-5-yl)quinolin-4-amine derivatives as novel VEGFR-2 kinase inhibitors.
    Shi L; Wu TT; Wang Z; Xue JY; Xu YG
    Eur J Med Chem; 2014 Sep; 84():698-707. PubMed ID: 25064347
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives as selective c-Met inhibitors.
    Wang X; Jiang N; Zhao S; Xi S; Wang J; Jing T; Zhang W; Guo M; Gong P; Zhai X
    Bioorg Med Chem; 2017 Feb; 25(3):886-896. PubMed ID: 28011202
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of Rogaratinib (BAY 1163877): a pan-FGFR Inhibitor.
    Collin MP; Lobell M; Hübsch W; Brohm D; Schirok H; Jautelat R; Lustig K; Bömer U; Vöhringer V; Héroult M; Grünewald S; Hess-Stumpp H
    ChemMedChem; 2018 Mar; 13(5):437-445. PubMed ID: 29451369
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and evaluate of novel dual FGFR1 and HDAC inhibitors bearing an indazole scaffold.
    Liu J; Qian C; Zhu Y; Cai J; He Y; Li J; Wang T; Zhu H; Li Z; Li W; Hu L
    Bioorg Med Chem; 2018 Feb; 26(3):747-757. PubMed ID: 29317150
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and evaluation of 2-phenylisothiazolidin-3-one-1,1-dioxides as a new class of human protein kinase CK2 inhibitors.
    Chekanov MO; Ostrynska OV; Synyugin AR; Bdzhola VG; Yarmoluk SM
    J Enzyme Inhib Med Chem; 2014 Jun; 29(3):338-43. PubMed ID: 23578312
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.