187 related articles for article (PubMed ID: 25742366)
1. Identification of multiple structurally distinct, nonpeptidic small molecule inhibitors of protein arginine deiminase 3 using a substrate-based fragment method.
Jamali H; Khan HA; Stringer JR; Chowdhury S; Ellman JA
J Am Chem Soc; 2015 Mar; 137(10):3616-21. PubMed ID: 25742366
[TBL] [Abstract][Full Text] [Related]
2. Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.
Knuckley B; Causey CP; Jones JE; Bhatia M; Dreyton CJ; Osborne TC; Takahara H; Thompson PR
Biochemistry; 2010 Jun; 49(23):4852-63. PubMed ID: 20469888
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors.
Jones JE; Slack JL; Fang P; Zhang X; Subramanian V; Causey CP; Coonrod SA; Guo M; Thompson PR
ACS Chem Biol; 2012 Jan; 7(1):160-5. PubMed ID: 22004374
[TBL] [Abstract][Full Text] [Related]
4. Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors.
Jamali H; Khan HA; Tjin CC; Ellman JA
ACS Med Chem Lett; 2016 Sep; 7(9):847-51. PubMed ID: 27660689
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors.
Subramanian V; Knight JS; Parelkar S; Anguish L; Coonrod SA; Kaplan MJ; Thompson PR
J Med Chem; 2015 Feb; 58(3):1337-44. PubMed ID: 25559347
[TBL] [Abstract][Full Text] [Related]
6. Inhibitors of protein arginine deiminases and their efficacy in animal models of multiple sclerosis.
Sarswat A; Wasilewski E; Chakka SK; Bello AM; Caprariello AV; Muthuramu CM; Stys PK; Dunn SE; Kotra LP
Bioorg Med Chem; 2017 May; 25(9):2643-2656. PubMed ID: 28341402
[TBL] [Abstract][Full Text] [Related]
7. Discovery of Novel Potential Reversible Peptidyl Arginine Deiminase Inhibitor.
Aliko A; Kamińska M; Falkowski K; Bielecka E; Benedyk-Machaczka M; Malicki S; Kozieł J; Wong A; Bryzek D; Kantyka T; Mydel P
Int J Mol Sci; 2019 May; 20(9):. PubMed ID: 31052493
[TBL] [Abstract][Full Text] [Related]
8. An interplay of structure and intrinsic disorder in the functionality of peptidylarginine deiminases, a family of key autoimmunity-related enzymes.
Alghamdi M; Al Ghamdi KA; Khan RH; Uversky VN; Redwan EM
Cell Mol Life Sci; 2019 Dec; 76(23):4635-4662. PubMed ID: 31342121
[TBL] [Abstract][Full Text] [Related]
9. Peptidyl Arginine Deiminases and Neurodegenerative Diseases.
Tu R; Grover HM; Kotra LP
Curr Med Chem; 2016; 23(2):104-14. PubMed ID: 26577926
[TBL] [Abstract][Full Text] [Related]
10. Discovery of structurally-diverse inhibitor scaffolds by high-throughput screening of a fragment library with dimethylarginine dimethylaminohydrolase.
Linsky TW; Fast W
Bioorg Med Chem; 2012 Sep; 20(18):5550-8. PubMed ID: 22921743
[TBL] [Abstract][Full Text] [Related]
11. Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability.
Lange S; Gögel S; Leung KY; Vernay B; Nicholas AP; Causey CP; Thompson PR; Greene ND; Ferretti P
Dev Biol; 2011 Jul; 355(2):205-14. PubMed ID: 21539830
[TBL] [Abstract][Full Text] [Related]
12. Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential.
Jones JE; Causey CP; Knuckley B; Slack-Noyes JL; Thompson PR
Curr Opin Drug Discov Devel; 2009 Sep; 12(5):616-27. PubMed ID: 19736621
[TBL] [Abstract][Full Text] [Related]
13. Halogen Bonding Increases the Potency and Isozyme Selectivity of Protein Arginine Deiminase 1 Inhibitors.
Mondal S; Gong X; Zhang X; Salinger AJ; Zheng L; Sen S; Weerapana E; Zhang X; Thompson PR
Angew Chem Int Ed Engl; 2019 Sep; 58(36):12476-12480. PubMed ID: 31276611
[TBL] [Abstract][Full Text] [Related]
14. Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis.
Méchin MC; Cau L; Galliano MF; Daunes-Marion S; Poigny S; Vidaluc JL; Bessou-Touya S; Takahara H; Serre G; Duplan H; Simon M
J Dermatol Sci; 2016 Feb; 81(2):101-6. PubMed ID: 26616205
[TBL] [Abstract][Full Text] [Related]
15. When will small molecule lactate dehydrogenase inhibitors realize their potential in the cancer clinic?
Rani R; Kumar V
Future Med Chem; 2017 Jul; 9(11):1113-1115. PubMed ID: 28722474
[No Abstract] [Full Text] [Related]
16. Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery.
Erlanson DA; Arndt JW; Cancilla MT; Cao K; Elling RA; English N; Friedman J; Hansen SK; Hession C; Joseph I; Kumaravel G; Lee WC; Lind KE; McDowell RS; Miatkowski K; Nguyen C; Nguyen TB; Park S; Pathan N; Penny DM; Romanowski MJ; Scott D; Silvian L; Simmons RL; Tangonan BT; Yang W; Sun L
Bioorg Med Chem Lett; 2011 May; 21(10):3078-83. PubMed ID: 21459573
[TBL] [Abstract][Full Text] [Related]
17. Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation.
Dreyton CJ; Anderson ED; Subramanian V; Boger DL; Thompson PR
Bioorg Med Chem; 2014 Feb; 22(4):1362-9. PubMed ID: 24440480
[TBL] [Abstract][Full Text] [Related]
18. Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2.
Corbett JW; Freeman-Cook KD; Elliott R; Vajdos F; Rajamohan F; Kohls D; Marr E; Zhang H; Tong L; Tu M; Murdande S; Doran SD; Houser JA; Song W; Jones CJ; Coffey SB; Buzon L; Minich ML; Dirico KJ; Tapley S; McPherson RK; Sugarman E; Harwood HJ; Esler W
Bioorg Med Chem Lett; 2010 Apr; 20(7):2383-8. PubMed ID: 20219367
[TBL] [Abstract][Full Text] [Related]
19. A fluopol-ABPP HTS assay to identify PAD inhibitors.
Knuckley B; Jones JE; Bachovchin DA; Slack J; Causey CP; Brown SJ; Rosen H; Cravatt BF; Thompson PR
Chem Commun (Camb); 2010 Oct; 46(38):7175-7. PubMed ID: 20740228
[TBL] [Abstract][Full Text] [Related]
20. Three isozymes of peptidylarginine deiminase in the chicken: molecular cloning, characterization, and tissue distribution.
Shimizu A; Handa K; Honda T; Abe N; Kojima T; Takahara H
Comp Biochem Physiol B Biochem Mol Biol; 2014 Jan; 167():65-73. PubMed ID: 24161753
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
