BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

525 related articles for article (PubMed ID: 25742700)

  • 1. Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation.
    Alinari L; Mahasenan KV; Yan F; Karkhanis V; Chung JH; Smith EM; Quinion C; Smith PL; Kim L; Patton JT; Lapalombella R; Yu B; Wu Y; Roy S; De Leo A; Pileri S; Agostinelli C; Ayers L; Bradner JE; Chen-Kiang S; Elemento O; Motiwala T; Majumder S; Byrd JC; Jacob S; Sif S; Li C; Baiocchi RA
    Blood; 2015 Apr; 125(16):2530-43. PubMed ID: 25742700
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein arginine methyltransferase 5 represses tumor suppressor miRNAs that down-regulate CYCLIN D1 and c-MYC expression in aggressive B-cell lymphoma.
    Karkhanis V; Alinari L; Ozer HG; Chung J; Zhang X; Sif S; Baiocchi RA
    J Biol Chem; 2020 Jan; 295(5):1165-1180. PubMed ID: 31822509
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The dual epigenetic role of PRMT5 in acute myeloid leukemia: gene activation and repression via histone arginine methylation.
    Tarighat SS; Santhanam R; Frankhouser D; Radomska HS; Lai H; Anghelina M; Wang H; Huang X; Alinari L; Walker A; Caligiuri MA; Croce CM; Li L; Garzon R; Li C; Baiocchi RA; Marcucci G
    Leukemia; 2016 Apr; 30(4):789-99. PubMed ID: 26536822
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.
    Chung J; Karkhanis V; Tae S; Yan F; Smith P; Ayers LW; Agostinelli C; Pileri S; Denis GV; Baiocchi RA; Sif S
    J Biol Chem; 2013 Dec; 288(49):35534-47. PubMed ID: 24189068
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.
    Yan F; Alinari L; Lustberg ME; Martin LK; Cordero-Nieves HM; Banasavadi-Siddegowda Y; Virk S; Barnholtz-Sloan J; Bell EH; Wojton J; Jacob NK; Chakravarti A; Nowicki MO; Wu X; Lapalombella R; Datta J; Yu B; Gordon K; Haseley A; Patton JT; Smith PL; Ryu J; Zhang X; Mo X; Marcucci G; Nuovo G; Kwon CH; Byrd JC; Chiocca EA; Li C; Sif S; Jacob S; Lawler S; Kaur B; Baiocchi RA
    Cancer Res; 2014 Mar; 74(6):1752-65. PubMed ID: 24453002
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/β-catenin and AKT/GSK3β proliferative signaling.
    Chung J; Karkhanis V; Baiocchi RA; Sif S
    J Biol Chem; 2019 May; 294(19):7692-7710. PubMed ID: 30885941
    [TBL] [Abstract][Full Text] [Related]  

  • 7. hTERT inhibition triggers Epstein-Barr virus lytic cycle and apoptosis in immortalized and transformed B cells: a basis for new therapies.
    Giunco S; Dolcetti R; Keppel S; Celeghin A; Indraccolo S; Dal Col J; Mastorci K; De Rossi A
    Clin Cancer Res; 2013 Apr; 19(8):2036-47. PubMed ID: 23444223
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells.
    Wang L; Pal S; Sif S
    Mol Cell Biol; 2008 Oct; 28(20):6262-77. PubMed ID: 18694959
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cell cycle arrest and lytic induction of EBV-transformed B lymphoblastoid cells by a histone deacetylase inhibitor, Trichostatin A.
    Seo JS; Cho NY; Kim HR; Tsurumi T; Jang YS; Lee WK; Lee SK
    Oncol Rep; 2008 Jan; 19(1):93-8. PubMed ID: 18097580
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation.
    Choi KC; Jung MG; Lee YH; Yoon JC; Kwon SH; Kang HB; Kim MJ; Cha JH; Kim YJ; Jun WJ; Lee JM; Yoon HG
    Cancer Res; 2009 Jan; 69(2):583-92. PubMed ID: 19147572
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PRMT5 restricts hepatitis B virus replication through epigenetic repression of covalently closed circular DNA transcription and interference with pregenomic RNA encapsidation.
    Zhang W; Chen J; Wu M; Zhang X; Zhang M; Yue L; Li Y; Liu J; Li B; Shen F; Wang Y; Bai L; Protzer U; Levrero M; Yuan Z
    Hepatology; 2017 Aug; 66(2):398-415. PubMed ID: 28236308
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases.
    Prabhu L; Chen L; Wei H; Demir Ö; Safa A; Zeng L; Amaro RE; O'Neil BH; Zhang ZY; Lu T
    Mol Biosyst; 2017 Nov; 13(12):2509-2520. PubMed ID: 29099132
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of interferon-stimulated genes on the IL-4 response axis by Epstein-Barr virus infected human b cells; relevance to cellular transformation.
    Smith N; Tierney R; Wei W; Vockerodt M; Murray PG; Woodman CB; Rowe M
    PLoS One; 2013; 8(5):e64868. PubMed ID: 23724103
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Validation of protein arginine methyltransferase 5 (PRMT5) as a candidate therapeutic target in the spontaneous canine model of non-Hodgkin lymphoma.
    Sloan SL; Renaldo KA; Long M; Chung JH; Courtney LE; Shilo K; Youssef Y; Schlotter S; Brown F; Klamer BG; Zhang X; Yilmaz AS; Ozer HG; Valli VE; Vaddi K; Scherle P; Alinari L; Kisseberth WC; Baiocchi RA
    PLoS One; 2021; 16(5):e0250839. PubMed ID: 33989303
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel PRMT5-mediated arginine methylations of HSP90A are essential for maintenance of HSP90A function in NDRG2
    Ichikawa T; Shanab O; Nakahata S; Shimosaki S; Manachai N; Ono M; Iha H; Shimoda K; Morishita K
    Biochim Biophys Acta Mol Cell Res; 2020 Feb; 1867(2):118615. PubMed ID: 31765670
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oxidative stress enables Epstein-Barr virus-induced B-cell transformation by posttranscriptional regulation of viral and cellular growth-promoting factors.
    Chen X; Kamranvar SA; Masucci MG
    Oncogene; 2016 Jul; 35(29):3807-16. PubMed ID: 26592445
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer.
    Liu X; Zhang J; Liu L; Jiang Y; Ji J; Yan R; Zhu Z; Yu Y
    Biochim Biophys Acta Mol Basis Dis; 2018 Sep; 1864(9 Pt B):2835-2844. PubMed ID: 29802960
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pre-stimulation of CD81 expression by resting B cells increases proliferation following EBV infection, but the overexpression of CD81 induces the apoptosis of EBV-transformed B cells.
    Park GB; Kim D; Park SJ; Lee HK; Kim JH; Kim YS; Park SG; Choi IH; Yoon SH; Lee YJ; Paeng S; Hur DY
    Int J Mol Med; 2015 Dec; 36(6):1464-78. PubMed ID: 26498453
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NF-κB directly mediates epigenetic deregulation of common microRNAs in Epstein-Barr virus-mediated transformation of B-cells and in lymphomas.
    Vento-Tormo R; Rodríguez-Ubreva J; Lisio LD; Islam AB; Urquiza JM; Hernando H; López-Bigas N; Shannon-Lowe C; Martínez N; Montes-Moreno S; Piris MA; Ballestar E
    Nucleic Acids Res; 2014; 42(17):11025-39. PubMed ID: 25200074
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Latent membrane protein 1 of Epstein-Barr virus plays an important role in the serum starvation resistance of Epstein-Barr virus-immortalized B lymphocytes.
    Park CH; Kim HR; Kim J; Jang SH; Lee KY; Chung GH; Jang YS
    J Cell Biochem; 2004 Mar; 91(4):777-85. PubMed ID: 14991769
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.