BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 25746449)

  • 1. Alternative solutions and new scenarios for translesion DNA synthesis by human PrimPol.
    Martínez-Jiménez MI; García-Gómez S; Bebenek K; Sastre-Moreno G; Calvo PA; Díaz-Talavera A; Kunkel TA; Blanco L
    DNA Repair (Amst); 2015 May; 29():127-38. PubMed ID: 25746449
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PolDIP2 interacts with human PrimPol and enhances its DNA polymerase activities.
    Guilliam TA; Bailey LJ; Brissett NC; Doherty AJ
    Nucleic Acids Res; 2016 Apr; 44(7):3317-29. PubMed ID: 26984527
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro lesion bypass by human PrimPol.
    Makarova AV; Boldinova EO; Belousova EA; Lavrik OI
    DNA Repair (Amst); 2018 Oct; 70():18-24. PubMed ID: 30098578
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure and mechanism of human PrimPol, a DNA polymerase with primase activity.
    Rechkoblit O; Gupta YK; Malik R; Rajashankar KR; Johnson RE; Prakash L; Prakash S; Aggarwal AK
    Sci Adv; 2016 Oct; 2(10):e1601317. PubMed ID: 27819052
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA Damage Tolerance by Eukaryotic DNA Polymerase and Primase PrimPol.
    Boldinova EO; Wanrooij PH; Shilkin ES; Wanrooij S; Makarova AV
    Int J Mol Sci; 2017 Jul; 18(7):. PubMed ID: 28754021
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The invariant glutamate of human PrimPol DxE motif is critical for its Mn
    Calvo PA; Sastre-Moreno G; Perpiñá C; Guerra S; Martínez-Jiménez MI; Blanco L
    DNA Repair (Amst); 2019 May; 77():65-75. PubMed ID: 30889508
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular basis for PrimPol recruitment to replication forks by RPA.
    Guilliam TA; Brissett NC; Ehlinger A; Keen BA; Kolesar P; Taylor EM; Bailey LJ; Lindsay HD; Chazin WJ; Doherty AJ
    Nat Commun; 2017 May; 8():15222. PubMed ID: 28534480
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondrial DNA replication: a PrimPol perspective.
    Bailey LJ; Doherty AJ
    Biochem Soc Trans; 2017 Apr; 45(2):513-529. PubMed ID: 28408491
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PrimPol: A Breakthrough among DNA Replication Enzymes and a Potential New Target for Cancer Therapy.
    Díaz-Talavera A; Montero-Conde C; Leandro-García LJ; Robledo M
    Biomolecules; 2022 Feb; 12(2):. PubMed ID: 35204749
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The DNA ligands Arg47 and Arg76 are crucial for catalysis by human PrimPol.
    Boldinova EO; Manukyan АА; Makarova АV
    DNA Repair (Amst); 2021 Apr; 100():103048. PubMed ID: 33571927
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism of DNA primer synthesis by human PrimPol.
    Blanco L; Calvo PA; Diaz-Talavera A; Carvalho G; Calero N; Martínez-Carrón A; Velázquez-Ruiz C; Villadangos S; Guerra S; Martínez-Jiménez MI
    Enzymes; 2019; 45():289-310. PubMed ID: 31627881
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular dissection of the domain architecture and catalytic activities of human PrimPol.
    Keen BA; Jozwiakowski SK; Bailey LJ; Bianchi J; Doherty AJ
    Nucleic Acids Res; 2014 May; 42(9):5830-45. PubMed ID: 24682820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A unique arginine cluster in PolDIP2 enhances nucleotide binding and DNA synthesis by PrimPol.
    Kasho K; Stojkovič G; Velázquez-Ruiz C; Martínez-Jiménez MI; Doimo M; Laurent T; Berner A; Pérez-Rivera AE; Jenninger L; Blanco L; Wanrooij S
    Nucleic Acids Res; 2021 Feb; 49(4):2179-2191. PubMed ID: 33533925
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of Human DNA Primase-Polymerase PrimPol.
    Boldinova EO; Makarova AV
    Biochemistry (Mosc); 2023 Aug; 88(8):1139-1155. PubMed ID: 37758313
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins.
    Guilliam TA; Jozwiakowski SK; Ehlinger A; Barnes RP; Rudd SG; Bailey LJ; Skehel JM; Eckert KA; Chazin WJ; Doherty AJ
    Nucleic Acids Res; 2015 Jan; 43(2):1056-68. PubMed ID: 25550423
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kinetic analysis of human PrimPol DNA polymerase activity reveals a generally error-prone enzyme capable of accurately bypassing 7,8-dihydro-8-oxo-2'-deoxyguanosine.
    Zafar MK; Ketkar A; Lodeiro MF; Cameron CE; Eoff RL
    Biochemistry; 2014 Oct; 53(41):6584-94. PubMed ID: 25255211
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Translesion activity of PrimPol on DNA with cisplatin and DNA-protein cross-links.
    Boldinova EO; Yudkina AV; Shilkin ES; Gagarinskaya DI; Baranovskiy AG; Tahirov TH; Zharkov DO; Makarova AV
    Sci Rep; 2021 Sep; 11(1):17588. PubMed ID: 34475447
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Repriming of DNA synthesis at stalled replication forks by human PrimPol.
    Mourón S; Rodriguez-Acebes S; Martínez-Jiménez MI; García-Gómez S; Chocrón S; Blanco L; Méndez J
    Nat Struct Mol Biol; 2013 Dec; 20(12):1383-9. PubMed ID: 24240614
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Significant impact of divalent metal ions on the fidelity, sugar selectivity, and drug incorporation efficiency of human PrimPol.
    Tokarsky EJ; Wallenmeyer PC; Phi KK; Suo Z
    DNA Repair (Amst); 2017 Jan; 49():51-59. PubMed ID: 27989484
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain-terminating nucleosides.
    Kobayashi K; Guilliam TA; Tsuda M; Yamamoto J; Bailey LJ; Iwai S; Takeda S; Doherty AJ; Hirota K
    Cell Cycle; 2016 Aug; 15(15):1997-2008. PubMed ID: 27230014
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.