BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

396 related articles for article (PubMed ID: 25753158)

  • 1. ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
    Ji S; Qin Y; Shi S; Liu X; Hu H; Zhou H; Gao J; Zhang B; Xu W; Liu J; Liang D; Liu L; Liu C; Long J; Zhou H; Chiao PJ; Xu J; Ni Q; Gao D; Yu X
    Cell Res; 2015 May; 25(5):561-73. PubMed ID: 25753158
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion.
    Jin X; Yang C; Fan P; Xiao J; Zhang W; Zhan S; Liu T; Wang D; Wu H
    J Biol Chem; 2017 Apr; 292(15):6269-6280. PubMed ID: 28242758
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
    J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.
    Isobe T; Hattori T; Kitagawa K; Uchida C; Kotake Y; Kosugi I; Oda T; Kitagawa M
    J Biol Chem; 2009 Oct; 284(41):27766-27779. PubMed ID: 19679664
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
    Inuzuka H; Shaik S; Onoyama I; Gao D; Tseng A; Maser RS; Zhai B; Wan L; Gutierrez A; Lau AW; Xiao Y; Christie AL; Aster J; Settleman J; Gygi SP; Kung AL; Look T; Nakayama KI; DePinho RA; Wei W
    Nature; 2011 Mar; 471(7336):104-9. PubMed ID: 21368833
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3).
    Kannan MB; Dodard-Friedman I; Blank V
    J Biol Chem; 2015 Oct; 290(43):26292-302. PubMed ID: 26306035
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation.
    Zhao D; Zheng HQ; Zhou Z; Chen C
    Cancer Res; 2010 Jun; 70(11):4728-38. PubMed ID: 20484041
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ras activity regulates cyclin E degradation by the Fbw7 pathway.
    Minella AC; Welcker M; Clurman BE
    Proc Natl Acad Sci U S A; 2005 Jul; 102(27):9649-54. PubMed ID: 15980150
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Physiological Functions of FBW7 in Metabolism.
    Zhang J; Kong DH; Huang X; Yu R; Yang Y
    Horm Metab Res; 2022 May; 54(5):280-287. PubMed ID: 35533672
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.
    Biswas M; Phan D; Watanabe M; Chan JY
    J Biol Chem; 2011 Nov; 286(45):39282-9. PubMed ID: 21953459
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.
    Suryo Rahmanto A; Savov V; Brunner A; Bolin S; Weishaupt H; Malyukova A; Rosén G; Čančer M; Hutter S; Sundström A; Kawauchi D; Jones DT; Spruck C; Taylor MD; Cho YJ; Pfister SM; Kool M; Korshunov A; Swartling FJ; Sangfelt O
    EMBO J; 2016 Oct; 35(20):2192-2212. PubMed ID: 27625374
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.
    Min SH; Lau AW; Lee TH; Inuzuka H; Wei S; Huang P; Shaik S; Lee DY; Finn G; Balastik M; Chen CH; Luo M; Tron AE; Decaprio JA; Zhou XZ; Wei W; Lu KP
    Mol Cell; 2012 Jun; 46(6):771-83. PubMed ID: 22608923
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
    Welcker M; Orian A; Jin J; Grim JE; Harper JW; Eisenman RN; Clurman BE
    Proc Natl Acad Sci U S A; 2004 Jun; 101(24):9085-90. PubMed ID: 15150404
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.
    Liu N; Li H; Li S; Shen M; Xiao N; Chen Y; Wang Y; Wang W; Wang R; Wang Q; Sun J; Wang P
    J Biol Chem; 2010 Jun; 285(24):18858-67. PubMed ID: 20388706
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection.
    Wang JY; Zhu B; Patterson LL; Rogan MR; Kibler CE; McBride JW
    PLoS Pathog; 2020 Apr; 16(4):e1008541. PubMed ID: 32353058
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α.
    Trausch-Azar JS; Abed M; Orian A; Schwartz AL
    J Cell Physiol; 2015 Apr; 230(4):842-52. PubMed ID: 25204433
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation.
    Wang R; Wang Y; Liu N; Ren C; Jiang C; Zhang K; Yu S; Chen Y; Tang H; Deng Q; Fu C; Wang Y; Li R; Liu M; Pan W; Wang P
    Cell Res; 2013 Jun; 23(6):803-19. PubMed ID: 23507969
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
    Xiao D; Yue M; Su H; Ren P; Jiang J; Li F; Hu Y; Du H; Liu H; Qing G
    Mol Cell; 2016 Nov; 64(3):493-506. PubMed ID: 27773673
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
    Wertz IE; Kusam S; Lam C; Okamoto T; Sandoval W; Anderson DJ; Helgason E; Ernst JA; Eby M; Liu J; Belmont LD; Kaminker JS; O'Rourke KM; Pujara K; Kohli PB; Johnson AR; Chiu ML; Lill JR; Jackson PK; Fairbrother WJ; Seshagiri S; Ludlam MJ; Leong KG; Dueber EC; Maecker H; Huang DC; Dixit VM
    Nature; 2011 Mar; 471(7336):110-4. PubMed ID: 21368834
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of the ubiquitin ligase Fbw7 in cancer progression.
    Cheng Y; Li G
    Cancer Metastasis Rev; 2012 Jun; 31(1-2):75-87. PubMed ID: 22124735
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.