These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 25755265)

  • 21. Inhibition of herpes simplex virus type 1 by the CDK6 inhibitor PD-0332991 (palbociclib) through the control of SAMHD1.
    Badia R; Angulo G; Riveira-Muñoz E; Pujantell M; Puig T; Ramirez C; Torres-Torronteras J; Martí R; Pauls E; Clotet B; Ballana E; Esté JA
    J Antimicrob Chemother; 2016 Feb; 71(2):387-94. PubMed ID: 26542306
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Palbociclib, a selective inhibitor of cyclin-dependent kinase4/6, blocks HIV-1 reverse transcription through the control of sterile α motif and HD domain-containing protein-1 (SAMHD1) activity.
    Pauls E; Badia R; Torres-Torronteras J; Ruiz A; Permanyer M; Riveira-Muñoz E; Clotet B; Marti R; Ballana E; Esté JA
    AIDS; 2014 Sep; 28(15):2213-22. PubMed ID: 25036183
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase.
    Zhu C; Gao W; Zhao K; Qin X; Zhang Y; Peng X; Zhang L; Dong Y; Zhang W; Li P; Wei W; Gong Y; Yu XF
    Nat Commun; 2013; 4():2722. PubMed ID: 24217394
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Structural characterization and directed modification of Sus scrofa SAMHD1 reveal the mechanism underlying deoxynucleotide regulation.
    Kong J; Wang MM; He SY; Peng X; Qin XH
    FEBS J; 2019 Oct; 286(19):3844-3857. PubMed ID: 31152619
    [TBL] [Abstract][Full Text] [Related]  

  • 25. SAMHD1 host restriction factor: a link with innate immune sensing of retrovirus infection.
    Sze A; Olagnier D; Lin R; van Grevenynghe J; Hiscott J
    J Mol Biol; 2013 Dec; 425(24):4981-94. PubMed ID: 24161438
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Molecular dynamics investigation of DNA fragments bound to the anti-HIV protein SAMHD1 reveals alterations in allosteric communications.
    Thapa G; Bhattacharya A; Bhattacharya S
    J Mol Graph Model; 2024 Jun; 129():108748. PubMed ID: 38452417
    [TBL] [Abstract][Full Text] [Related]  

  • 27. High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
    Klemm BP; Sikkema AP; Hsu AL; Horng JC; Hall TMT; Borgnia MJ; Schaaper RM
    J Biol Chem; 2022 Jul; 298(7):102073. PubMed ID: 35643313
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Pharmacological Modulation of SAMHD1 Activity by CDK4/6 Inhibitors Improves Anticancer Therapy.
    Castellví M; Felip E; Ezeonwumelu IJ; Badia R; Garcia-Vidal E; Pujantell M; Gutiérrez-Chamorro L; Teruel I; Martínez-Cardús A; Clotet B; Riveira-Muñoz E; Margelí M; Ballana E
    Cancers (Basel); 2020 Mar; 12(3):. PubMed ID: 32197329
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The N-terminal SAM domain of the dNTPase SAMHD1 is not required for inhibition by small molecule TH6342.
    Dirks C; Bwanika HC; Jemth AS; Zhang SM; Rudd SG
    Nucleosides Nucleotides Nucleic Acids; 2024 Jun; ():1-6. PubMed ID: 38830230
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Interferon-stimulated gene factor 3 complex is required for the induction of sterile α motif and HD domain-containing protein 1 expression by interferon-α in SMMC-7721 cells.
    Zhu M; Lu J; Dong X; Zheng N; Li T; Chen Z; Pan X; Zhu Y; Yan H; Shen Y; Ying S; Hu C
    Mol Med Rep; 2015 Nov; 12(5):7176-80. PubMed ID: 26397446
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Phosphorylation of murine SAMHD1 regulates its antiretroviral activity.
    Wittmann S; Behrendt R; Eissmann K; Volkmann B; Thomas D; Ebert T; Cribier A; Benkirane M; Hornung V; Bouzas NF; Gramberg T
    Retrovirology; 2015 Dec; 12():103. PubMed ID: 26667483
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Regulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implications.
    Kohnken R; Kodigepalli KM; Wu L
    Mol Cancer; 2015 Sep; 14():176. PubMed ID: 26416562
    [TBL] [Abstract][Full Text] [Related]  

  • 33. SAMHD1, the Aicardi-Goutières syndrome gene and retroviral restriction factor, is a phosphorolytic ribonuclease rather than a hydrolytic ribonuclease.
    Ryoo J; Hwang SY; Choi J; Oh C; Ahn K
    Biochem Biophys Res Commun; 2016 Sep; 477(4):977-981. PubMed ID: 27387229
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay.
    Surviladze Z; Waller A; Wu Y; Romero E; Edwards BS; Wandinger-Ness A; Sklar LA
    J Biomol Screen; 2010 Jan; 15(1):10-20. PubMed ID: 20008126
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel.
    Zhang SM; Paulin CBJ; Shu H; Yagüe-Capilla M; Michel M; Marttila P; Ortis F; Bwanika HC; Dirks C; Venkatram RP; Wiita E; Jemth AS; Almlöf I; Loseva O; Hormann FM; Koolmeister T; Linde E; Lee S; Llona-Minguez S; Haraldsson M; Axelsson H; Strömberg K; Homan EJ; Scobie M; Lundbäck T; Helleday T; Rudd SG
    iScience; 2024 Feb; 27(2):108907. PubMed ID: 38318365
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dasatinib inhibits HIV-1 replication through the interference of SAMHD1 phosphorylation in CD4+ T cells.
    Bermejo M; López-Huertas MR; García-Pérez J; Climent N; Descours B; Ambrosioni J; Mateos E; Rodríguez-Mora S; Rus-Bercial L; Benkirane M; Miró JM; Plana M; Alcamí J; Coiras M
    Biochem Pharmacol; 2016 Apr; 106():30-45. PubMed ID: 26851491
    [TBL] [Abstract][Full Text] [Related]  

  • 37. SAMHD1 is down regulated in lung cancer by methylation and inhibits tumor cell proliferation.
    Wang JL; Lu FZ; Shen XY; Wu Y; Zhao LT
    Biochem Biophys Res Commun; 2014 Dec; 455(3-4):229-33. PubMed ID: 25449277
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1)-facilitated HIV restriction in astrocytes is regulated by miRNA-181a.
    Pilakka-Kanthikeel S; Raymond A; Atluri VS; Sagar V; Saxena SK; Diaz P; Chevelon S; Concepcion M; Nair M
    J Neuroinflammation; 2015 Apr; 12():66. PubMed ID: 25890101
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Development of a cell-based, high-throughput screening assay for ATM kinase inhibitors.
    Guo K; Shelat AA; Guy RK; Kastan MB
    J Biomol Screen; 2014 Apr; 19(4):538-46. PubMed ID: 24464432
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Allosteric substrate activation of SAMHD1 shapes deoxynucleotide triphosphate imbalances by interconnecting the depletion and biosynthesis of different dNTPs.
    McCown C; Yu CH; Ivanov DN
    bioRxiv; 2023 Nov; ():. PubMed ID: 38014186
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.