BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 25757092)

  • 1. Luotonin-A based quinazolinones cause apoptosis and senescence via HDAC inhibition and activation of tumor suppressor proteins in HeLa cells.
    Venkatesh R; Ramaiah MJ; Gaikwad HK; Janardhan S; Bantu R; Nagarapu L; Sastry GN; Ganesh AR; Bhadra M
    Eur J Med Chem; 2015 Apr; 94():87-101. PubMed ID: 25757092
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Changes in histone deacetylase (HDAC) expression patterns and activity of HDAC inhibitors in urothelial cancers.
    Niegisch G; Knievel J; Koch A; Hader C; Fischer U; Albers P; Schulz WA
    Urol Oncol; 2013 Nov; 31(8):1770-9. PubMed ID: 22944197
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histone deacetylase 2 modulates p53 transcriptional activities through regulation of p53-DNA binding activity.
    Harms KL; Chen X
    Cancer Res; 2007 Apr; 67(7):3145-52. PubMed ID: 17409421
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and biological evaluation of quinoline derivatives as HDAC class I inhibitors.
    Chen C; Hou X; Wang G; Pan W; Yang X; Zhang Y; Fang H
    Eur J Med Chem; 2017 Jun; 133():11-23. PubMed ID: 28371677
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel class I histone deacetylase inhibitor, I-7ab, induces apoptosis and arrests cell cycle progression in human colorectal cancer cells.
    Yang L; Liang Q; Shen K; Ma L; An N; Deng W; Fei Z; Liu J
    Biomed Pharmacother; 2015 Apr; 71():70-8. PubMed ID: 25960218
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Methotrexate induces apoptosis through p53/p21-dependent pathway and increases E-cadherin expression through downregulation of HDAC/EZH2.
    Huang WY; Yang PM; Chang YF; Marquez VE; Chen CC
    Biochem Pharmacol; 2011 Feb; 81(4):510-7. PubMed ID: 21114963
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Scriptaid cause histone deacetylase inhibition and cell cycle arrest in HeLa cancer cells: A study on structural and functional aspects.
    Janaki Ramaiah M; Naushad SM; Lavanya A; Srinivas C; Anjana Devi T; Sampathkumar S; Dharan DB; Bhadra MP
    Gene; 2017 Sep; 627():379-386. PubMed ID: 28668345
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of a series of small molecules as potent histone deacetylase inhibitors.
    Zhang L; Wang X; Li X; Xu W
    J Enzyme Inhib Med Chem; 2014 Jun; 29(3):333-7. PubMed ID: 23534931
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of the cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by Zac1 through the antagonistic regulators p53 and histone deacetylase 1 in HeLa Cells.
    Liu PY; Chan JY; Lin HC; Wang SL; Liu ST; Ho CL; Chang LC; Huang SM
    Mol Cancer Res; 2008 Jul; 6(7):1204-14. PubMed ID: 18644983
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of potent HDAC inhibitors based on chlamydocin with inhibitory effects on cell migration.
    Wang S; Li X; Wei Y; Xiu Z; Nishino N
    ChemMedChem; 2014 Mar; 9(3):627-37. PubMed ID: 24285590
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitory selectivity among class I HDACs has a major impact on inflammatory gene expression in macrophages.
    Cao F; Zwinderman MRH; van Merkerk R; Ettema PE; Quax WJ; Dekker FJ
    Eur J Med Chem; 2019 Sep; 177():457-466. PubMed ID: 31181405
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery and preliminary evaluation of 2-aminobenzamide and hydroxamate derivatives containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors.
    Cai J; Wei H; Hong KH; Wu X; Cao M; Zong X; Li L; Sun C; Chen J; Ji M
    Eur J Med Chem; 2015; 96():1-13. PubMed ID: 25874326
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insights into the molecular interactions of thymoquinone with histone deacetylase: evaluation of the therapeutic intervention potential against breast cancer.
    Parbin S; Shilpi A; Kar S; Pradhan N; Sengupta D; Deb M; Rath SK; Patra SK
    Mol Biosyst; 2016 Jan; 12(1):48-58. PubMed ID: 26540192
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery, bioactivity and docking simulation of Vorinostat analogues containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors and antitumor agents.
    Cai J; Wei H; Hong KH; Wu X; Zong X; Cao M; Wang P; Li L; Sun C; Chen B; Zhou G; Chen J; Ji M
    Bioorg Med Chem; 2015 Jul; 23(13):3457-71. PubMed ID: 25953722
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antiproliferative and proapoptotic activities of 4-hydroxybenzoic acid-based inhibitors of histone deacetylases.
    Seidel C; Schnekenburger M; Dicato M; Diederich M
    Cancer Lett; 2014 Feb; 343(1):134-46. PubMed ID: 24080339
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel N-hydroxyfurylacrylamide-based histone deacetylase (HDAC) inhibitors with branched CAP group (Part 2).
    Feng T; Wang H; Su H; Lu H; Yu L; Zhang X; Sun H; You Q
    Bioorg Med Chem; 2013 Sep; 21(17):5339-54. PubMed ID: 23820574
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition enhancer of zeste homologue 2 promotes senescence and apoptosis induced by doxorubicin in p53 mutant gastric cancer cells.
    Bai J; Ma M; Cai M; Xu F; Chen J; Wang G; Shuai X; Tao K
    Cell Prolif; 2014 Jun; 47(3):211-8. PubMed ID: 24738879
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential Regulation of Telomerase Reverse Transcriptase Promoter Activation and Protein Degradation by Histone Deacetylase Inhibition.
    Qing H; Aono J; Findeisen HM; Jones KL; Heywood EB; Bruemmer D
    J Cell Physiol; 2016 Jun; 231(6):1276-82. PubMed ID: 26505494
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ginsenoside 20(s)-Rh2 as potent natural histone deacetylase inhibitors suppressing the growth of human leukemia cells.
    Liu ZH; Li J; Xia J; Jiang R; Zuo GW; Li XP; Chen Y; Xiong W; Chen DL
    Chem Biol Interact; 2015 Dec; 242():227-34. PubMed ID: 26482938
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of pyridone-based histone deacetylase inhibitors: approaches for metabolic stability.
    Cho M; Choi E; Yang JS; Lee C; Seo JJ; Kim BS; Oh SJ; Kim HM; Lee K; Park SK; Kwon HJ; Han G
    ChemMedChem; 2013 Feb; 8(2):272-9. PubMed ID: 23292995
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.