BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 25759518)

  • 1. Measurement of lysine-specific demethylase-1 activity in the nuclear extracts by flow-injection based time-of-flight mass spectrometry.
    Sakane C; Ohta H; Shidoji Y
    J Clin Biochem Nutr; 2015 Mar; 56(2):123-31. PubMed ID: 25759518
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heterogeneous Antibody-Based Activity Assay for Lysine Specific Demethylase 1 (LSD1) on a Histone Peptide Substrate.
    Schmitt ML; Ladwein KI; Carlino L; Schulz-Fincke J; Willmann D; Metzger E; Schilcher P; Imhof A; Schüle R; Sippl W; Jung M
    J Biomol Screen; 2014 Jul; 19(6):973-8. PubMed ID: 24687155
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of lysine-specific demethylase 1 by the acyclic diterpenoid geranylgeranoic acid and its derivatives.
    Sakane C; Okitsu T; Wada A; Sagami H; Shidoji Y
    Biochem Biophys Res Commun; 2014 Jan; 444(1):24-9. PubMed ID: 24406160
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytoplasmic translocation of nuclear LSD1 (
    Yabuta S; Shidoji Y
    Hepat Oncol; 2019 Jun; 6(2):HEP13. PubMed ID: 31205679
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Silencing of LSD1 gene modulates histone methylation and acetylation and induces the apoptosis of JeKo-1 and MOLT-4 cells.
    Zou ZK; Huang YQ; Zou Y; Zheng XK; Ma XD
    Int J Mol Med; 2017 Aug; 40(2):319-328. PubMed ID: 28627608
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of phenylcyclopropylamine compounds by enzymatic assay of lysine-specific demethylase 2 in the presence of NPAC peptide.
    Kakizawa T; Mizukami T; Itoh Y; Hasegawa M; Sasaki R; Suzuki T
    Bioorg Med Chem Lett; 2016 Feb; 26(4):1193-5. PubMed ID: 26794039
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A).
    Li Z; Ding L; Li Z; Wang Z; Suo F; Shen D; Zhao T; Sun X; Wang J; Liu Y; Ma L; Zhao B; Geng P; Yu B; Zheng Y; Liu H
    Acta Pharm Sin B; 2019 Jul; 9(4):794-808. PubMed ID: 31384539
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lysine-Specific Demethylase 1A (KDM1A/LSD1): Product Recognition and Kinetic Analysis of Full-Length Histones.
    Burg JM; Gonzalez JJ; Maksimchuk KR; McCafferty DG
    Biochemistry; 2016 Mar; 55(11):1652-62. PubMed ID: 26673564
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, Synthesis, and In Vitro Evaluation of Novel Histone H3 Peptide-Based LSD1 Inactivators Incorporating α,α-Disubstituted Amino Acids with γ-Turn-Inducing Structures.
    Ota Y; Kakizawa T; Itoh Y; Suzuki T
    Molecules; 2018 May; 23(5):. PubMed ID: 29734782
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-throughput TR-FRET assays for identifying inhibitors of LSD1 and JMJD2C histone lysine demethylases.
    Yu V; Fisch T; Long AM; Tang J; Lee JH; Hierl M; Chen H; Yakowec P; Schwandner R; Emkey R
    J Biomol Screen; 2012 Jan; 17(1):27-38. PubMed ID: 21859682
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lysine-Specific Demethylase 1 (LSD1/KDM1A) Is a Novel Target Gene of c-Myc.
    Nagasaka M; Tsuzuki K; Ozeki Y; Tokugawa M; Ohoka N; Inoue Y; Hayashi H
    Biol Pharm Bull; 2019; 42(3):481-488. PubMed ID: 30828079
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine.
    Yang M; Culhane JC; Szewczuk LM; Jalili P; Ball HL; Machius M; Cole PA; Yu H
    Biochemistry; 2007 Jul; 46(27):8058-65. PubMed ID: 17569509
    [TBL] [Abstract][Full Text] [Related]  

  • 13. trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1.
    Schmidt DM; McCafferty DG
    Biochemistry; 2007 Apr; 46(14):4408-16. PubMed ID: 17367163
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.
    Amano Y; Kikuchi M; Sato S; Yokoyama S; Umehara T; Umezawa N; Higuchi T
    Bioorg Med Chem; 2017 May; 25(9):2617-2624. PubMed ID: 28336409
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.
    Shi Y; Lan F; Matson C; Mulligan P; Whetstine JR; Cole PA; Casero RA; Shi Y
    Cell; 2004 Dec; 119(7):941-53. PubMed ID: 15620353
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation.
    Laurent B; Ruitu L; Murn J; Hempel K; Ferrao R; Xiang Y; Liu S; Garcia BA; Wu H; Wu F; Steen H; Shi Y
    Mol Cell; 2015 Mar; 57(6):957-970. PubMed ID: 25684206
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GR and LSD1/KDM1A-Targeted Gene Activation Requires Selective H3K4me2 Demethylation at Enhancers.
    Clark EA; Wu F; Chen Y; Kang P; Kaiser UB; Fang R; Shi YG
    Cell Rep; 2019 Jun; 27(12):3522-3532.e3. PubMed ID: 31216473
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Folate deficiency affects histone methylation.
    Garcia BA; Luka Z; Loukachevitch LV; Bhanu NV; Wagner C
    Med Hypotheses; 2016 Mar; 88():63-7. PubMed ID: 26880641
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer.
    Majello B; Gorini F; Saccà CD; Amente S
    Cancers (Basel); 2019 Mar; 11(3):. PubMed ID: 30866496
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1 .
    Mimasu S; Umezawa N; Sato S; Higuchi T; Umehara T; Yokoyama S
    Biochemistry; 2010 Aug; 49(30):6494-503. PubMed ID: 20568732
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.