499 related articles for article (PubMed ID: 25760531)
1. Benzydamine N-oxygenation as an index for flavin-containing monooxygenase activity and benzydamine N-demethylation by cytochrome P450 enzymes in liver microsomes from rats, dogs, monkeys, and humans.
Taniguchi-Takizawa T; Shimizu M; Kume T; Yamazaki H
Drug Metab Pharmacokinet; 2015 Feb; 30(1):64-9. PubMed ID: 25760531
[TBL] [Abstract][Full Text] [Related]
2. Drug oxygenation activities mediated by liver microsomal flavin-containing monooxygenases 1 and 3 in humans, monkeys, rats, and minipigs.
Yamazaki M; Shimizu M; Uno Y; Yamazaki H
Biochem Pharmacol; 2014 Jul; 90(2):159-65. PubMed ID: 24821112
[TBL] [Abstract][Full Text] [Related]
3. In vitro evaluation of potential in vivo probes for human flavin-containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms.
Lang DH; Rettie AE
Br J Clin Pharmacol; 2000 Oct; 50(4):311-4. PubMed ID: 11012553
[TBL] [Abstract][Full Text] [Related]
4. Benzydamine N-oxidation as an index reaction reflecting FMO activity in human liver microsomes and impact of FMO3 polymorphisms on enzyme activity.
Störmer E; Roots I; Brockmöller J
Br J Clin Pharmacol; 2000 Dec; 50(6):553-61. PubMed ID: 11136294
[TBL] [Abstract][Full Text] [Related]
5. Flavin-containing monooxygenase activity in hepatocytes and microsomes: in vitro characterization and in vivo scaling of benzydamine clearance.
Fisher MB; Yoon K; Vaughn ML; Strelevitz TJ; Foti RS
Drug Metab Dispos; 2002 Oct; 30(10):1087-93. PubMed ID: 12228184
[TBL] [Abstract][Full Text] [Related]
6. Activation and deactivation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by cytochrome P450 enzymes and flavin-containing monooxygenases in common marmosets (Callithrix jacchus).
Uehara S; Uno Y; Inoue T; Murayama N; Shimizu M; Sasaki E; Yamazaki H
Drug Metab Dispos; 2015 May; 43(5):735-42. PubMed ID: 25735838
[TBL] [Abstract][Full Text] [Related]
7. Benzydamine N-oxygenation as a measure of flavin-containing monooxygenase activity.
Yeung CK; Rettie AE
Methods Mol Biol; 2006; 320():157-62. PubMed ID: 16719388
[TBL] [Abstract][Full Text] [Related]
8. Potential for drug interactions mediated by polymorphic flavin-containing monooxygenase 3 in human livers.
Shimizu M; Shiraishi A; Sato A; Nagashima S; Yamazaki H
Drug Metab Pharmacokinet; 2015 Feb; 30(1):70-4. PubMed ID: 25760532
[TBL] [Abstract][Full Text] [Related]
9. Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase.
Uehara S; Shimizu M; Uno Y; Inoue T; Sasaki E; Yamazaki H
Drug Metab Dispos; 2017 May; 45(5):497-500. PubMed ID: 28258069
[TBL] [Abstract][Full Text] [Related]
10. Species Differences in the Oxidative Desulfurization of a Thiouracil-Based Irreversible Myeloperoxidase Inactivator by Flavin-Containing Monooxygenase Enzymes.
Eng H; Sharma R; Wolford A; Di L; Ruggeri RB; Buckbinder L; Conn EL; Dalvie DK; Kalgutkar AS
Drug Metab Dispos; 2016 Aug; 44(8):1262-9. PubMed ID: 27079250
[TBL] [Abstract][Full Text] [Related]
11. Stereoselectivity in the cytochrome P450-dependent N-demethylation and flavin monooxygenase-dependent N-oxidation of N,N-dimethylamphetamine.
Lee S; Yoo HH; In MK; Jin C; Kim DH
Arch Pharm Res; 2013 Nov; 36(11):1385-91. PubMed ID: 23640382
[TBL] [Abstract][Full Text] [Related]
12. In vitro hepatic metabolism of ABT-418 in chimpanzee (Pan troglodytes). A unique pattern of microsomal flavin-containing monooxygenase-dependent stereoselective N'-oxidation.
Rodrigues AD; Kukulka MJ; Ferrero JL; Cashman JR
Drug Metab Dispos; 1995 Oct; 23(10):1143-52. PubMed ID: 8654204
[TBL] [Abstract][Full Text] [Related]
13. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
Mani C; Gelboin HV; Park SS; Pearce R; Parkinson A; Kupfer D
Drug Metab Dispos; 1993; 21(4):645-56. PubMed ID: 8104124
[TBL] [Abstract][Full Text] [Related]
14. Trimethylamine N-oxygenation and N-demethylation in rat liver microsomes.
Gut I; Conney AH
Biochem Pharmacol; 1993 Jul; 46(2):239-44. PubMed ID: 8347145
[TBL] [Abstract][Full Text] [Related]
15. Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP 1A2 and flavin-containing monooxygenase in N-demethylation of caffeine; identified by using inducer treated rat liver microsomes that are characterized with testosterone metabolic patterns.
Chung WG; Roh HK; Kim HM; Cha YN
Chem Biol Interact; 1998 May; 113(1):1-14. PubMed ID: 9630843
[TBL] [Abstract][Full Text] [Related]
16. Hepatic Flavin-Containing Monooxygenase 3 Enzyme Suppressed by Type 1 Allergy-Produced Nitric Oxide.
Tanino T; Bando T; Komada A; Nojiri Y; Okada Y; Ueda Y; Sakurai E
Drug Metab Dispos; 2017 Nov; 45(11):1189-1196. PubMed ID: 28760731
[TBL] [Abstract][Full Text] [Related]
17. Methionine S-oxidation in human and rabbit liver microsomes: evidence for a high-affinity methionine S-oxidase activity that is distinct from flavin-containing monooxygenase 3.
Ripp SL; Itagaki K; Philpot RM; Elfarra AA
Arch Biochem Biophys; 1999 Jul; 367(2):322-32. PubMed ID: 10395751
[TBL] [Abstract][Full Text] [Related]
18. Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450.
Chung WG; Park CS; Roh HK; Lee WK; Cha YN
Jpn J Pharmacol; 2000 Oct; 84(2):213-20. PubMed ID: 11128045
[TBL] [Abstract][Full Text] [Related]
19. An assay of flavin-containing monooxygenase activity with benzydamine N-oxidation.
Kawaji A; Ohara K; Takabatake E
Anal Biochem; 1993 Nov; 214(2):409-12. PubMed ID: 8109727
[TBL] [Abstract][Full Text] [Related]
20. Flavin-containing monooxygenase mediated metabolism of benzydamine in perfused brain and liver.
Kawaji A; Isobe M; Tochino Y; Takabatake E; Chikaoka Y; Nomura Y; Tamura M
Biochim Biophys Acta; 1998 Sep; 1425(1):41-6. PubMed ID: 9813235
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]