BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 25762023)

  • 1. CINPA1 is an inhibitor of constitutive androstane receptor that does not activate pregnane X receptor.
    Cherian MT; Lin W; Wu J; Chen T
    Mol Pharmacol; 2015 May; 87(5):878-89. PubMed ID: 25762023
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human pregnane X receptor is activated by dibenzazepine carbamate-based inhibitors of constitutive androstane receptor.
    Jeske J; Windshügel B; Thasler WE; Schwab M; Burk O
    Arch Toxicol; 2017 Jun; 91(6):2375-2390. PubMed ID: 28289823
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CINPA1 binds directly to constitutive androstane receptor and inhibits its activity.
    Cherian MT; Chai SC; Wright WC; Singh A; Alexandra Casal M; Zheng J; Wu J; Lee RE; Griffin PR; Chen T
    Biochem Pharmacol; 2018 Jun; 152():211-223. PubMed ID: 29608908
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
    Hoffart E; Ghebreghiorghis L; Nussler AK; Thasler WE; Weiss TS; Schwab M; Burk O
    Br J Pharmacol; 2012 Mar; 165(5):1595-608. PubMed ID: 21913896
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.
    Kast HR; Goodwin B; Tarr PT; Jones SA; Anisfeld AM; Stoltz CM; Tontonoz P; Kliewer S; Willson TM; Edwards PA
    J Biol Chem; 2002 Jan; 277(4):2908-15. PubMed ID: 11706036
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.
    Chen Y; Tang Y; Guo C; Wang J; Boral D; Nie D
    Biochem Pharmacol; 2012 Apr; 83(8):1112-26. PubMed ID: 22326308
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
    Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
    Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
    [TBL] [Abstract][Full Text] [Related]  

  • 8. GW4064, an agonist of farnesoid X receptor, represses CYP3A4 expression in human hepatocytes by inducing small heterodimer partner expression.
    Zhang S; Pan X; Jeong H
    Drug Metab Dispos; 2015 May; 43(5):743-8. PubMed ID: 25725071
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
    PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification and Characterization of CINPA1 Metabolites Facilitates Structure-Activity Studies of the Constitutive Androstane Receptor.
    Cherian MT; Yang L; Chai SC; Lin W; Chen T
    Drug Metab Dispos; 2016 Nov; 44(11):1759-1770. PubMed ID: 27519550
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
    Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
    J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
    Moore LB; Parks DJ; Jones SA; Bledsoe RK; Consler TG; Stimmel JB; Goodwin B; Liddle C; Blanchard SG; Willson TM; Collins JL; Kliewer SA
    J Biol Chem; 2000 May; 275(20):15122-7. PubMed ID: 10748001
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Xenobiotic Nuclear Receptors Pregnane X Receptor and Constitutive Androstane Receptor Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier.
    Whyte-Allman SK; Hoque MT; Jenabian MA; Routy JP; Bendayan R
    J Pharmacol Exp Ther; 2017 Dec; 363(3):324-335. PubMed ID: 28970358
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential activation of pregnane X receptor and constitutive androstane receptor by buprenorphine in primary human hepatocytes and HepG2 cells.
    Li L; Hassan HE; Tolson AH; Ferguson SS; Eddington ND; Wang H
    J Pharmacol Exp Ther; 2010 Dec; 335(3):562-71. PubMed ID: 20829393
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The xenobiotic receptors PXR and CAR in liver physiology, an update.
    Cai X; Young GM; Xie W
    Biochim Biophys Acta Mol Basis Dis; 2021 Jun; 1867(6):166101. PubMed ID: 33600998
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR).
    Anderson LE; Dring AM; Hamel LD; Stoner MA
    Toxicol Lett; 2011 Apr; 202(2):148-54. PubMed ID: 21315811
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflammation.
    Kittayaruksakul S; Zhao W; Xu M; Ren S; Lu J; Wang J; Downes M; Evans RM; Venkataramanan R; Chatsudthipong V; Xie W
    Pharm Res; 2013 Sep; 30(9):2199-208. PubMed ID: 23896737
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of CINPA1 analogs as novel and potent inverse agonists of constitutive androstane receptor.
    Lin W; Yang L; Chai SC; Lu Y; Chen T
    Eur J Med Chem; 2016 Jan; 108():505-528. PubMed ID: 26717202
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of constitutive androstane receptor in Toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transporters.
    Shah P; Guo T; Moore DD; Ghose R
    Drug Metab Dispos; 2014 Jan; 42(1):172-81. PubMed ID: 24194512
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.